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Items: 1 to 20 of 87

1.

Evaluation of the intestinal toxicity and transport of xenobiotics utilizing precision-cut slices.

Niu X, de Graaf IA, Groothuis GM.

Xenobiotica. 2013 Jan;43(1):73-83. doi: 10.3109/00498254.2012.729870. Review.

PMID:
23106567
2.

Precision-cut intestinal slices as in vitro tool for studies on drug metabolism.

Groothuis GM, de Graaf IA.

Curr Drug Metab. 2013 Jan;14(1):112-9. Review.

PMID:
22497569
3.

Evaluation of the metabolism and hepatotoxicity of xenobiotics utilizing precision-cut slices.

Lake BG, Price RJ.

Xenobiotica. 2013 Jan;43(1):41-53. doi: 10.3109/00498254.2012.734643. Review.

PMID:
23131042
4.

Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies.

Morin JP, Baste JM, Gay A, Crochemore C, Corbière C, Monteil C.

Xenobiotica. 2013 Jan;43(1):63-72. doi: 10.3109/00498254.2012.727043. Review.

PMID:
23030793
5.

Precision-cut intestinal slices: alternative model for drug transport, metabolism, and toxicology research.

Li M, de Graaf IA, Groothuis GM.

Expert Opin Drug Metab Toxicol. 2016;12(2):175-90. doi: 10.1517/17425255.2016.1125882. Review.

PMID:
26750630
6.

Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.

Ioannides C.

Xenobiotica. 2013 Jan;43(1):15-28. doi: 10.3109/00498254.2012.698766. Review.

PMID:
22742738
7.

A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.

van Midwoud PM, Merema MT, Verpoorte E, Groothuis GM.

Lab Chip. 2010 Oct 21;10(20):2778-86. doi: 10.1039/c0lc00043d.

PMID:
20835427
8.

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies.

de Graaf IA, Olinga P, de Jager MH, Merema MT, de Kanter R, van de Kerkhof EG, Groothuis GM.

Nat Protoc. 2010 Sep;5(9):1540-51. doi: 10.1038/nprot.2010.111.

PMID:
20725069
9.

Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Xu C, Li CY, Kong AN.

Arch Pharm Res. 2005 Mar;28(3):249-68. Review.

PMID:
15832810
10.

Suppression of drug-metabolizing enzymes and efflux transporters in the intestine of endotoxin-treated rats.

Kalitsky-Szirtes J, Shayeganpour A, Brocks DR, Piquette-Miller M.

Drug Metab Dispos. 2004 Jan;32(1):20-7.

11.

The role of the intestine in drug metabolism and pharmacokinetics: an industry perspective.

Fisher MB, Labissiere G.

Curr Drug Metab. 2007 Oct;8(7):694-9. Review.

PMID:
17979657
12.

In vitro methods to study intestinal drug metabolism.

van de Kerkhof EG, de Graaf IA, Groothuis GM.

Curr Drug Metab. 2007 Oct;8(7):658-75. Review.

PMID:
17979654
13.

Frog intestinal sac as an in vitro method for the assessment of intestinal permeability in humans: Application to carrier transported drugs.

Franco M, Lopedota A, Trapani A, Cutrignelli A, Meleleo D, Micelli S, Trapani G.

Int J Pharm. 2008 Mar 20;352(1-2):182-8.

PMID:
18055143
14.

Preparation and culture of precision-cut organ slices from human and animal.

Fisher RL, Vickers AE.

Xenobiotica. 2013 Jan;43(1):8-14. doi: 10.3109/00498254.2012.728013. Review.

PMID:
23030812
15.

Sex-dependent metabolism of xenobiotics.

Mugford CA, Kedderis GL.

Drug Metab Rev. 1998 Aug;30(3):441-98. Review.

PMID:
9710703
16.

Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues.

de Kanter R, Monshouwer M, Meijer DK, Groothuis GM.

Curr Drug Metab. 2002 Feb;3(1):39-59. Review.

PMID:
11878310
17.

Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.

Elferink MG, Olinga P, van Leeuwen EM, Bauerschmidt S, Polman J, Schoonen WG, Heisterkamp SH, Groothuis GM.

Toxicol Appl Pharmacol. 2011 May 15;253(1):57-69. doi: 10.1016/j.taap.2011.03.010.

PMID:
21420995
18.

Evaluation of drug-induced injury and human response in precision-cut tissue slices.

Vickers AE, Fisher RL.

Xenobiotica. 2013 Jan;43(1):29-40. doi: 10.3109/00498254.2012.732714. Review.

PMID:
23094640
19.

Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D.

Pharm Res. 2006 Aug;23(8):1675-86. Review.

PMID:
16841194
20.
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