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Items: 1 to 20 of 165

1.

MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response.

Pang X, Samten B, Cao G, Wang X, Tvinnereim AR, Chen XL, Howard ST.

J Bacteriol. 2013 Jan;195(1):66-75. doi: 10.1128/JB.01067-12. Epub 2012 Oct 26.

2.

EspR, a regulator of the ESX-1 secretion system in Mycobacterium tuberculosis, is directly regulated by the two-component systems MprAB and PhoPR.

Cao G, Howard ST, Zhang P, Wang X, Chen XL, Samten B, Pang X.

Microbiology. 2015 Mar;161(Pt 3):477-89. doi: 10.1099/mic.0.000023. Epub 2014 Dec 23.

PMID:
25536998
3.

EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.

Chen JM, Boy-Röttger S, Dhar N, Sweeney N, Buxton RS, Pojer F, Rosenkrands I, Cole ST.

J Bacteriol. 2012 Feb;194(4):884-93. doi: 10.1128/JB.06417-11. Epub 2011 Dec 9.

4.

Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis.

Hunt DM, Sweeney NP, Mori L, Whalan RH, Comas I, Norman L, Cortes T, Arnvig KB, Davis EO, Stapleton MR, Green J, Buxton RS.

J Bacteriol. 2012 May;194(9):2307-20. doi: 10.1128/JB.00142-12. Epub 2012 Mar 2.

5.

The β-propeller gene Rv1057 of Mycobacterium tuberculosis has a complex promoter directly regulated by both the MprAB and TrcRS two-component systems.

Pang X, Cao G, Neuenschwander PF, Haydel SE, Hou G, Howard ST.

Tuberculosis (Edinb). 2011 Dec;91 Suppl 1:S142-9. doi: 10.1016/j.tube.2011.10.024. Epub 2011 Nov 17.

6.

Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses.

Samten B, Wang X, Barnes PF.

Tuberculosis (Edinb). 2009 Dec;89 Suppl 1:S74-6. doi: 10.1016/S1472-9792(09)70017-4.

PMID:
20006311
7.

Functional analysis of the EspR binding sites upstream of espR in Mycobacterium tuberculosis.

Cao G, Howard ST, Zhang P, Hou G, Pang X.

Curr Microbiol. 2013 Nov;67(5):572-9. doi: 10.1007/s00284-013-0404-8. Epub 2013 Jun 7.

PMID:
23743602
8.

A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.

McLaughlin B, Chon JS, MacGurn JA, Carlsson F, Cheng TL, Cox JS, Brown EJ.

PLoS Pathog. 2007 Aug 3;3(8):e105.

9.

MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c.

Bretl DJ, He H, Demetriadou C, White MJ, Penoske RM, Salzman NH, Zahrt TC.

Infect Immun. 2012 Sep;80(9):3018-33. doi: 10.1128/IAI.00520-12. Epub 2012 Jun 11.

10.

EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP.

Anil Kumar V, Goyal R, Bansal R, Singh N, Sevalkar RR, Kumar A, Sarkar D.

J Biol Chem. 2016 Sep 2;291(36):19018-30. doi: 10.1074/jbc.M116.746289. Epub 2016 Jul 21.

11.

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability.

Di Luca M, Bottai D, Batoni G, Orgeur M, Aulicino A, Counoupas C, Campa M, Brosch R, Esin S.

PLoS One. 2012;7(12):e52059. doi: 10.1371/journal.pone.0052059. Epub 2012 Dec 17.

12.
13.

Mutually dependent secretion of proteins required for mycobacterial virulence.

Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10676-81. Epub 2005 Jul 19.

14.

Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence.

Tufariello JM, Chapman JR, Kerantzas CA, Wong KW, Vilchèze C, Jones CM, Cole LE, Tinaztepe E, Thompson V, Fenyö D, Niederweis M, Ueberheide B, Philips JA, Jacobs WR Jr.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E348-57. doi: 10.1073/pnas.1523321113. Epub 2016 Jan 4.

16.

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

Blasco B, Chen JM, Hartkoorn R, Sala C, Uplekar S, Rougemont J, Pojer F, Cole ST.

PLoS Pathog. 2012;8(3):e1002621. doi: 10.1371/journal.ppat.1002621. Epub 2012 Mar 29.

17.

Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis.

He H, Bretl DJ, Penoske RM, Anderson DM, Zahrt TC.

J Bacteriol. 2011 Oct;193(19):5105-18. doi: 10.1128/JB.05562-11. Epub 2011 Aug 5.

18.

Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis.

Pang X, Vu P, Byrd TF, Ghanny S, Soteropoulos P, Mukamolova GV, Wu S, Samten B, Howard ST.

Microbiology. 2007 Apr;153(Pt 4):1229-42.

PMID:
17379732
19.

ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.

Bottai D, Majlessi L, Simeone R, Frigui W, Laurent C, Lenormand P, Chen J, Rosenkrands I, Huerre M, Leclerc C, Cole ST, Brosch R.

J Infect Dis. 2011 Apr 15;203(8):1155-64. doi: 10.1093/infdis/jiq089. Epub 2010 Dec 31.

PMID:
21196469
20.

Discovery of the type VII ESX-1 secretion needle?

Ates LS, Brosch R.

Mol Microbiol. 2017 Jan;103(1):7-12. doi: 10.1111/mmi.13579. Epub 2016 Nov 25.

PMID:
27859892

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