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Items: 1 to 20 of 112

1.

Blood pressure has only minor influence on aldosterone-induced oxidative stress and DNA damage in vivo.

Queisser N, Amann K, Hey V, Habib SL, Schupp N.

Free Radic Biol Med. 2013 Jan;54:17-25. doi: 10.1016/j.freeradbiomed.2012.10.549. Epub 2012 Oct 24.

PMID:
23104102
2.

Aldosterone induces fibrosis, oxidative stress and DNA damage in livers of male rats independent of blood pressure changes.

Queisser N, Happ K, Link S, Jahn D, Zimnol A, Geier A, Schupp N.

Toxicol Appl Pharmacol. 2014 Nov 1;280(3):399-407. doi: 10.1016/j.taap.2014.08.029. Epub 2014 Sep 7.

PMID:
25204689
3.

Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.

Brand S, Amann K, Mandel P, Zimnol A, Schupp N.

PLoS One. 2014 Dec 31;9(12):e115715. doi: 10.1371/journal.pone.0115715. eCollection 2014.

4.

Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system.

Iglarz M, Touyz RM, Viel EC, Amiri F, Schiffrin EL.

Am J Hypertens. 2004 Jul;17(7):597-603.

PMID:
15243979
5.

Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats.

Schupp N, Kolkhof P, Queisser N, Gärtner S, Schmid U, Kretschmer A, Hartmann E, Oli RG, Schäfer S, Stopper H.

FASEB J. 2011 Mar;25(3):968-78. doi: 10.1096/fj.10-173286. Epub 2010 Dec 6.

PMID:
21135038
6.

Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.

Shibata S, Nagase M, Yoshida S, Kawachi H, Fujita T.

Hypertension. 2007 Feb;49(2):355-64. Epub 2007 Jan 2.

7.

Aldosterone induces oxidative stress, oxidative DNA damage and NF-κB-activation in kidney tubule cells.

Queisser N, Oteiza PI, Stopper H, Oli RG, Schupp N.

Mol Carcinog. 2011 Feb;50(2):123-35. doi: 10.1002/mc.20710. Epub 2010 Dec 29.

PMID:
21229609
8.

Superoxide dismutase mimetic, tempol, aggravates renal injury in advanced-stage stroke-prone spontaneously hypertensive rats.

Sugama I, Kohagura K, Yamazato M, Nakamura T, Shinzato T, Ohya Y.

J Hypertens. 2014 Mar;32(3):534-41. doi: 10.1097/HJH.0000000000000064.

PMID:
24309490
9.

Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.

Wang H, Shimosawa T, Matsui H, Kaneko T, Ogura S, Uetake Y, Takenaka K, Yatomi Y, Fujita T.

J Hypertens. 2008 Jul;26(7):1453-62. doi: 10.1097/HJH.0b013e328300a232.

PMID:
18551023
10.

Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.

Park YM, Lim BH, Touyz RM, Park JB.

J Korean Med Sci. 2008 Dec;23(6):1039-45. doi: 10.3346/jkms.2008.23.6.1039. Epub 2008 Dec 24.

11.

Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats.

Kawarazaki H, Ando K, Fujita M, Matsui H, Nagae A, Muraoka K, Kawarasaki C, Fujita T.

Am J Physiol Renal Physiol. 2011 Jun;300(6):F1402-9. doi: 10.1152/ajprenal.00691.2010. Epub 2011 Apr 6.

12.

Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.

Fan YY, Kohno M, Hitomi H, Kitada K, Fujisawa Y, Yatabe J, Yatabe M, Felder RA, Ohsaki H, Rafiq K, Sherajee SJ, Noma T, Nishiyama A, Nakano D.

Endocrinology. 2011 Feb;152(2):680-8. doi: 10.1210/en.2010-0829. Epub 2010 Dec 29.

PMID:
21190955
13.

Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system.

Hirono Y, Yoshimoto T, Suzuki N, Sugiyama T, Sakurada M, Takai S, Kobayashi N, Shichiri M, Hirata Y.

Endocrinology. 2007 Apr;148(4):1688-96. Epub 2007 Jan 11.

PMID:
17218415
14.

Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats.

Nariai T, Fujita K, Mori M, Katayama S, Hori S, Matsui K.

Pharmacology. 2012;89(1-2):44-52. doi: 10.1159/000335559. Epub 2012 Feb 1.

PMID:
22302095
15.

Spironolactone improves angiotensin-induced vascular changes and oxidative stress.

Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL.

Hypertension. 2002 Oct;40(4):504-10.

16.

Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.

Lastra G, Whaley-Connell A, Manrique C, Habibi J, Gutweiler AA, Appesh L, Hayden MR, Wei Y, Ferrario C, Sowers JR.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E110-6. doi: 10.1152/ajpendo.00258.2007. Epub 2008 Apr 29.

17.

Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.

Noda K, Kobara M, Hamada J, Yoshifuji Y, Shiraishi T, Tanaka T, Wang J, Toba H, Nakata T.

J Cardiovasc Pharmacol. 2012 Aug;60(2):140-9. doi: 10.1097/FJC.0b013e318258f8ce.

PMID:
22549451
18.

Angiotensin II-induced hypertension dose-dependently leads to oxidative stress and DNA damage in mouse kidneys and hearts.

Brand S, Amann K, Schupp N.

J Hypertens. 2013 Feb;31(2):333-44. doi: 10.1097/HJH.0b013e32835ba77e.

PMID:
23249827
19.

Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases.

Queisser N, Schupp N.

Free Radic Biol Med. 2012 Jul 15;53(2):314-27. doi: 10.1016/j.freeradbiomed.2012.05.011. Epub 2012 May 15. Review.

PMID:
22609249
20.

Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation.

Wei Y, Whaley-Connell AT, Habibi J, Rehmer J, Rehmer N, Patel K, Hayden M, DeMarco V, Ferrario CM, Ibdah JA, Sowers JR.

Hypertension. 2009 Feb;53(2):158-65. doi: 10.1161/HYPERTENSIONAHA.108.121954. Epub 2008 Dec 29.

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