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Items: 1 to 20 of 294

1.

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response.

Jwa M, Chang P.

Nat Cell Biol. 2012 Nov;14(11):1223-30. doi: 10.1038/ncb2593. Epub 2012 Oct 28. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123.

2.

Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.

Pinkaew D, Chattopadhyay A, King MD, Chunhacha P, Liu Z, Stevenson HL, Chen Y, Sinthujaroen P, McDougal OM, Fujise K.

Nat Commun. 2017 May 26;8(1):18. doi: 10.1038/s41467-017-00029-1.

3.

Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.

Tay KH, Luan Q, Croft A, Jiang CC, Jin L, Zhang XD, Tseng HY.

Cell Signal. 2014 Feb;26(2):287-94. doi: 10.1016/j.cellsig.2013.11.008. Epub 2013 Nov 12.

PMID:
24240056
4.

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.

Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJ, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochem Pharmacol. 2016 Jun 1;109:27-47. doi: 10.1016/j.bcp.2016.04.001. Epub 2016 Apr 6.

PMID:
27059255
5.

Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress.

Nakato R, Ohkubo Y, Konishi A, Shibata M, Kaneko Y, Iwawaki T, Nakamura T, Lipton SA, Uehara T.

Sci Rep. 2015 Oct 8;5:14812. doi: 10.1038/srep14812.

6.

The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.

Ogborn DI, McKay BR, Crane JD, Parise G, Tarnopolsky MA.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15;307(6):R664-9. doi: 10.1152/ajpregu.00511.2013. Epub 2014 Jul 9.

PMID:
25009220
7.

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains.

Volmer R, van der Ploeg K, Ron D.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4628-33. doi: 10.1073/pnas.1217611110. Epub 2013 Mar 4.

8.

Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner.

Yang L, Sha H, Davisson RL, Qi L.

J Biol Chem. 2013 May 10;288(19):13631-8. doi: 10.1074/jbc.M113.462762. Epub 2013 Apr 2.

9.

IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.

Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.

Cell Signal. 2013 Nov;25(11):2136-46. doi: 10.1016/j.cellsig.2013.06.011. Epub 2013 Jun 29.

PMID:
23816533
10.

Molecular signal networks and regulating mechanisms of the unfolded protein response.

Gong J, Wang XZ, Wang T, Chen JJ, Xie XY, Hu H, Yu F, Liu HL, Jiang XY, Fan HD.

J Zhejiang Univ Sci B. 2017 Jan.;18(1):1-14. doi: 10.1631/jzus.B1600043. Review.

11.

HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response.

Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, Fusco DN, Brisac C, Schaefer EA, Cai D, Peng LF, Maneekarn N, Lin W, Chung RT.

Sci Rep. 2016 Mar 1;6:22487. doi: 10.1038/srep22487.

12.

Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.

13.

A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress-The Role of PERK Pathway.

Márton M, Kurucz A, Lizák B, Margittai É, Bánhegyi G, Kapuy O.

Int J Mol Sci. 2017 Jan 5;18(1). pii: E58. doi: 10.3390/ijms18010058.

14.

Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors.

Balakrishnan B, Sen D, Hareendran S, Roshini V, David S, Srivastava A, Jayandharan GR.

PLoS One. 2013;8(1):e53845. doi: 10.1371/journal.pone.0053845. Epub 2013 Jan 8.

15.

Ask1 gene deletion blocks maternal diabetes-induced endoplasmic reticulum stress in the developing embryo by disrupting the unfolded protein response signalosome.

Wang F, Wu Y, Gu H, Reece EA, Fang S, Gabbay-Benziv R, Aberdeen G, Yang P.

Diabetes. 2015 Mar;64(3):973-88. doi: 10.2337/db14-0409. Epub 2014 Sep 23.

16.

Generic membrane-spanning features endow IRE1α with responsiveness to membrane aberrancy.

Kono N, Amin-Wetzel N, Ron D.

Mol Biol Cell. 2017 Aug 15;28(17):2318-2332. doi: 10.1091/mbc.E17-03-0144. Epub 2017 Jun 14.

17.

PI 3-kinase regulatory subunits as regulators of the unfolded protein response.

Winnay JN, Kahn CR.

Methods Enzymol. 2011;490:147-58. doi: 10.1016/B978-0-12-385114-7.00009-X.

18.

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ.

J Clin Invest. 2005 Feb;115(2):268-81.

19.

TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling.

Sakabe I, Hu R, Jin L, Clarke R, Kasid UN.

Breast Cancer Res Treat. 2015 Sep;153(2):285-97. doi: 10.1007/s10549-015-3536-7. Epub 2015 Aug 13.

20.

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2011 Nov;22(22):4390-405. doi: 10.1091/mbc.E11-06-0510. Epub 2011 Sep 14.

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