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Items: 1 to 20 of 174

1.

Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication.

van Domselaar R, de Poot SA, Remmerswaal EB, Lai KW, ten Berge IJ, Bovenschen N.

Cell Death Differ. 2013 Mar;20(3):419-29. doi: 10.1038/cdd.2012.132. Epub 2012 Oct 26.

2.

Noncytotoxic inhibition of cytomegalovirus replication through NK cell protease granzyme M-mediated cleavage of viral phosphoprotein 71.

van Domselaar R, Philippen LE, Quadir R, Wiertz EJ, Kummer JA, Bovenschen N.

J Immunol. 2010 Dec 15;185(12):7605-13. doi: 10.4049/jimmunol.1001503. Epub 2010 Nov 8.

3.

All human granzymes target hnRNP K that is essential for tumor cell viability.

van Domselaar R, Quadir R, van der Made AM, Broekhuizen R, Bovenschen N.

J Biol Chem. 2012 Jun 29;287(27):22854-64. doi: 10.1074/jbc.M112.365692. Epub 2012 May 11.

4.

Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation.

Bovenschen N, Spijkers SN, Wensink AC, Schellens IM, van Domselaar R, van Baarle D.

Clin Immunol. 2014 Jan;150(1):1-11. doi: 10.1016/j.clim.2013.11.005. Epub 2013 Nov 18.

PMID:
24316590
5.

RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.

Xiaofei E, Stadler BM, Debatis M, Wang S, Lu S, Kowalik TF.

J Virol. 2012 May;86(10):5660-73. doi: 10.1128/JVI.06338-11. Epub 2012 Mar 21.

6.

CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication.

Martínez FP, Cruz R, Lu F, Plasschaert R, Deng Z, Rivera-Molina YA, Bartolomei MS, Lieberman PM, Tang Q.

J Virol. 2014 Jul;88(13):7389-401. doi: 10.1128/JVI.00845-14. Epub 2014 Apr 16.

7.

Human cytomegalovirus replication is strictly inhibited by siRNAs targeting UL54, UL97 or UL122/123 gene transcripts.

Hamilton ST, Milbradt J, Marschall M, Rawlinson WD.

PLoS One. 2014 Jun 2;9(6):e97231. doi: 10.1371/journal.pone.0097231. eCollection 2014.

8.

Human Cytomegalovirus IE2 Protein Disturbs Brain Development by the Dysregulation of Neural Stem Cell Maintenance and the Polarization of Migrating Neurons.

Han D, Byun SH, Kim J, Kwon M, Pleasure SJ, Ahn JH, Yoon K.

J Virol. 2017 Aug 10;91(17). pii: e00799-17. doi: 10.1128/JVI.00799-17. Print 2017 Sep 1.

10.

The interaction between human cytomegalovirus immediate-early gene 2 (IE2) protein and heterogeneous ribonucleoprotein A1.

Wang YF, Chen SC, Wu FY, Wu CW.

Biochem Biophys Res Commun. 1997 Mar 27;232(3):590-4.

PMID:
9126318
11.

Argonaute-2 enhances suppression of human cytomegalovirus replication by polycistronic short hairpin RNAs targeting UL46, UL70 and UL122.

Shao PL, Lu MY, Liau YJ, Chao MF, Chang LY, Lu CY, Kao CL, Chang SY, Chi YH, Huang LM.

Antivir Ther. 2011;16(5):741-9. doi: 10.3851/IMP1808.

PMID:
21817196
12.

The 5' Untranslated Region of the Major Immediate Early mRNA Is Necessary for Efficient Human Cytomegalovirus Replication.

Arend KC, Lenarcic EM, Moorman NJ.

J Virol. 2018 Mar 14;92(7). pii: e02128-17. doi: 10.1128/JVI.02128-17. Print 2018 Apr 1.

13.

Cell cycle arrest by human cytomegalovirus 86-kDa IE2 protein resembles premature senescence.

Noris E, Zannetti C, Demurtas A, Sinclair J, De Andrea M, Gariglio M, Landolfo S.

J Virol. 2002 Dec;76(23):12135-48.

14.

Association of human cytomegalovirus DNAaemia and specific granzyme B responses in lung transplant recipients.

Weseslindtner L, Kerschner H, Steinacher D, Kundi M, Jaksch P, Simon B, Hatos-Agyi L, Scheed A, Klepetko W, Puchhammer-Stöckl E.

Clin Exp Immunol. 2013 Sep;173(3):438-43. doi: 10.1111/cei.12123.

15.

Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment.

Massari S, Mercorelli B, Sancineto L, Sabatini S, Cecchetti V, Gribaudo G, Palù G, Pannecouque C, Loregian A, Tabarrini O.

ChemMedChem. 2013 Aug;8(8):1403-14. doi: 10.1002/cmdc.201300106. Epub 2013 Jun 11.

PMID:
23757191
16.

Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.

Xu S, Schafer X, Munger J.

J Virol. 2016 Apr 14;90(9):4346-4356. doi: 10.1128/JVI.00179-16. Print 2016 May.

17.

Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblasts.

Park JJ, Kim YE, Pham HT, Kim ET, Chung YH, Ahn JH.

J Gen Virol. 2007 Dec;88(Pt 12):3214-23.

PMID:
18024889
18.
19.

Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection.

Gibson L, Piccinini G, Lilleri D, Revello MG, Wang Z, Markel S, Diamond DJ, Luzuriaga K.

J Immunol. 2004 Feb 15;172(4):2256-64.

20.

Expansion of human cytomegalovirus (HCMV) immediate-early 1-specific CD8+ T cells and control of HCMV replication after allogeneic stem cell transplantation.

Sacre K, Nguyen S, Deback C, Carcelain G, Vernant JP, Leblond V, Autran B, Dhedin N.

J Virol. 2008 Oct;82(20):10143-52. doi: 10.1128/JVI.00688-08. Epub 2008 Aug 6.

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