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Items: 1 to 20 of 95

1.

MAGE-C2 promotes growth and tumorigenicity of melanoma cells, phosphorylation of KAP1, and DNA damage repair.

Bhatia N, Xiao TZ, Rosenthal KA, Siddiqui IA, Thiyagarajan S, Smart B, Meng Q, Zuleger CL, Mukhtar H, Kenney SC, Albertini MR, Jack Longley B.

J Invest Dermatol. 2013 Mar;133(3):759-67. doi: 10.1038/jid.2012.355.

2.

MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression.

Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ.

PLoS One. 2011;6(8):e23747. doi: 10.1371/journal.pone.0023747.

3.

MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines.

Yang B, O'Herrin SM, Wu J, Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ.

Cancer Res. 2007 Oct 15;67(20):9954-62.

4.

MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity.

Xiao TZ, Suh Y, Longley BJ.

Arch Biochem Biophys. 2014 Dec 1;563:136-44. doi: 10.1016/j.abb.2014.07.026.

5.

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation.

White D, Rafalska-Metcalf IU, Ivanov AV, Corsinotti A, Peng H, Lee SC, Trono D, Janicki SM, Rauscher FJ 3rd.

Mol Cancer Res. 2012 Mar;10(3):401-14. doi: 10.1158/1541-7786.MCR-11-0134.

6.

Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E.

Hao J, Song X, Wang J, Guo C, Li Y, Li B, Zhang Y, Yin Y.

Oncotarget. 2015 Dec 8;6(39):42028-39. doi: 10.18632/oncotarget.5973.

7.

Protein phosphatase PP4 is involved in NHEJ-mediated repair of DNA double-strand breaks.

Liu J, Xu L, Zhong J, Liao J, Li J, Xu X.

Cell Cycle. 2012 Jul 15;11(14):2643-9. doi: 10.4161/cc.20957.

PMID:
22732494
8.

RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner.

Kuo CY, Li X, Stark JM, Shih HM, Ann DK.

Cell Cycle. 2016;15(6):787-98. doi: 10.1080/15384101.2016.1138184.

9.

Expression of MAGE-C1/CT7 and MAGE-C2/CT10 predicts lymph node metastasis in melanoma patients.

Curioni-Fontecedro A, Nuber N, Mihic-Probst D, Seifert B, Soldini D, Dummer R, Knuth A, van den Broek M, Moch H.

PLoS One. 2011;6(6):e21418. doi: 10.1371/journal.pone.0021418.

10.

The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells.

Tseng HY, Chen LH, Ye Y, Tay KH, Jiang CC, Guo ST, Jin L, Hersey P, Zhang XD.

Carcinogenesis. 2012 Oct;33(10):1871-81. doi: 10.1093/carcin/bgs236.

11.

DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells.

Kalifa L, Gewandter JS, Staversky RJ, Sia EA, Brookes PS, O'Reilly MA.

Free Radic Biol Med. 2014 Oct;75:30-9. doi: 10.1016/j.freeradbiomed.2014.07.011.

12.

CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage.

Magni M, Ruscica V, Restelli M, Fontanella E, Buscemi G, Zannini L.

Oncotarget. 2015 Jul 10;6(19):17817-31.

13.

KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment.

Huh SJ, Chen YL, Friedman SL, Liao J, Huang HJ, Cavenee WK, Robertson GP.

J Natl Cancer Inst. 2010 Aug 4;102(15):1131-47. doi: 10.1093/jnci/djq218.

14.

Triptolide induced DNA damage in A375.S2 human malignant melanoma cells is mediated via reduction of DNA repair genes.

Chueh FS, Chen YL, Hsu SC, Yang JS, Hsueh SC, Ji BC, Lu HF, Chung JG.

Oncol Rep. 2013 Feb;29(2):613-8. doi: 10.3892/or.2012.2170.

PMID:
23233170
15.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
16.

Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.

Curioni-Fontecedro A, Pitocco R, Schoenewolf NL, Holzmann D, Soldini D, Dummer R, Calvieri S, Moch H, Mihic-Probst D, Fitsche A.

Biomed Res Int. 2015;2015:432479. doi: 10.1155/2015/432479.

17.

SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.

Li X, Lin HH, Chen H, Xu X, Shih HM, Ann DK.

Sci Signal. 2010 Apr 27;3(119):ra32. doi: 10.1126/scisignal.2000781.

18.

Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells.

Ivanov VN, Zhou H, Partridge MA, Hei TK.

Cancer Res. 2009 Apr 15;69(8):3510-9. doi: 10.1158/0008-5472.CAN-08-3883.

19.

Expression of BORIS in melanoma: lack of association with MAGE-A1 activation.

Kholmanskikh O, Loriot A, Brasseur F, De Plaen E, De Smet C.

Int J Cancer. 2008 Feb 15;122(4):777-84.

20.

Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.

Li X, Lee YK, Jeng JC, Yen Y, Schultz DC, Shih HM, Ann DK.

J Biol Chem. 2007 Dec 14;282(50):36177-89.

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