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Items: 1 to 20 of 87

1.

A computational systems analysis of factors regulating α cell glucagon secretion.

Fridlyand LE, Philipson LH.

Islets. 2012 Jul-Aug;4(4):262-83. doi: 10.4161/isl.22193. Epub 2012 Jul 1.

2.

K(ATP)-channels and glucose-regulated glucagon secretion.

Rorsman P, Salehi SA, Abdulkader F, Braun M, MacDonald PE.

Trends Endocrinol Metab. 2008 Oct;19(8):277-84. doi: 10.1016/j.tem.2008.07.003. Epub 2008 Sep 2. Review.

PMID:
18771934
3.

Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.

Ramracheya R, Ward C, Shigeto M, Walker JN, Amisten S, Zhang Q, Johnson PR, Rorsman P, Braun M.

Diabetes. 2010 Sep;59(9):2198-208. doi: 10.2337/db09-1505. Epub 2010 Jun 14.

4.

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

MacDonald PE, De Marinis YZ, Ramracheya R, Salehi A, Ma X, Johnson PR, Cox R, Eliasson L, Rorsman P.

PLoS Biol. 2007 Jun;5(6):e143.

5.

Minimal state models for ionic channels involved in glucagon secretion.

Gonzalez-Velez V, Gil A, Quesada I.

Math Biosci Eng. 2010 Oct;7(4):793-807. doi: 10.3934/mbe.2010.7.793.

PMID:
21077708
6.

Targeting of voltage-gated K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic alpha-cells: effects on glucagon stimulus-secretion coupling.

Xia F, Leung YM, Gaisano G, Gao X, Chen Y, Fox JE, Bhattacharjee A, Wheeler MB, Gaisano HY, Tsushima RG.

Endocrinology. 2007 May;148(5):2157-67. Epub 2007 Feb 15.

PMID:
17303668
7.

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.

Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P.

Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014.

8.

Paracrine regulation of glucagon secretion: the β/α/δ model.

Watts M, Ha J, Kimchi O, Sherman A.

Am J Physiol Endocrinol Metab. 2016 Apr 15;310(8):E597-E611. doi: 10.1152/ajpendo.00415.2015. Epub 2016 Feb 2.

9.

Mathematical modelling of local calcium and regulated exocytosis during inhibition and stimulation of glucagon secretion from pancreatic alpha-cells.

Montefusco F, Pedersen MG.

J Physiol. 2015 Oct 15;593(20):4519-30. doi: 10.1113/JP270777. Epub 2015 Sep 2.

10.

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?

Walker JN, Ramracheya R, Zhang Q, Johnson PR, Braun M, Rorsman P.

Diabetes Obes Metab. 2011 Oct;13 Suppl 1:95-105. doi: 10.1111/j.1463-1326.2011.01450.x. Review.

PMID:
21824262
11.

Glucose decouples intracellular Ca2+ activity from glucagon secretion in mouse pancreatic islet alpha-cells.

Le Marchand SJ, Piston DW.

PLoS One. 2012;7(10):e47084. doi: 10.1371/journal.pone.0047084. Epub 2012 Oct 15.

12.

The somatostatin receptor in human pancreatic β-cells.

Braun M.

Vitam Horm. 2014;95:165-93. doi: 10.1016/B978-0-12-800174-5.00007-7. Review.

PMID:
24559918
13.

Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes.

Quesada I, Tudurí E, Ripoll C, Nadal A.

J Endocrinol. 2008 Oct;199(1):5-19. doi: 10.1677/JOE-08-0290. Epub 2008 Jul 31. Review.

14.

Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

Göpel SO, Kanno T, Barg S, Weng XG, Gromada J, Rorsman P.

J Physiol. 2000 Nov 1;528(Pt 3):509-20.

15.

In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.

Huang YC, Rupnik MS, Karimian N, Herrera PL, Gilon P, Feng ZP, Gaisano HY.

Diabetes. 2013 Feb;62(2):519-30. doi: 10.2337/db11-0786. Epub 2012 Oct 5.

16.

Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells.

Olsen HL, Theander S, Bokvist K, Buschard K, Wollheim CB, Gromada J.

Endocrinology. 2005 Nov;146(11):4861-70. Epub 2005 Aug 4.

PMID:
16081632
17.
18.

Regulation of calcium in pancreatic α- and β-cells in health and disease.

Rorsman P, Braun M, Zhang Q.

Cell Calcium. 2012 Mar-Apr;51(3-4):300-8. doi: 10.1016/j.ceca.2011.11.006. Epub 2011 Dec 15. Review.

19.

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.

PMID:
12679159

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