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Items: 1 to 20 of 130

1.

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.

Rocha e Silva LF, Montoia A, Amorim RC, Melo MR, Henrique MC, Nunomura SM, Costa MR, Andrade Neto VF, Costa DS, Dantas G, Lavrado J, Moreira R, Paulo A, Pinto AC, Tadei WP, Zacardi RS, Eberlin MN, Pohlit AM.

Phytomedicine. 2012 Dec 15;20(1):71-6. doi: 10.1016/j.phymed.2012.09.008. Epub 2012 Oct 23.

2.

Recent developments in naturally derived antimalarials: cryptolepine analogues.

Wright CW.

J Pharm Pharmacol. 2007 Jun;59(6):899-904. Review.

PMID:
17637183
3.

In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta.

Cimanga K, De Bruyne T, Pieters L, Vlietinck AJ, Turger CA.

J Nat Prod. 1997 Jul;60(7):688-91.

PMID:
9249972
4.

Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C.

Ganfon H, Bero J, Tchinda AT, Gbaguidi F, Gbenou J, Moudachirou M, Frédérich M, Quetin-Leclercq J.

J Ethnopharmacol. 2012 May 7;141(1):411-7. doi: 10.1016/j.jep.2012.03.002. Epub 2012 Mar 13.

PMID:
22440261
5.

Antimalarial and safety evaluation of extracts from Toddalia asiatica (L) Lam. (Rutaceae).

Orwa JA, Ngeny L, Mwikwabe NM, Ondicho J, Jondiko IJ.

J Ethnopharmacol. 2013 Jan 30;145(2):587-90. doi: 10.1016/j.jep.2012.11.034. Epub 2012 Dec 1.

PMID:
23207061
6.

Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids.

dos Santos Torres ZE, Silveira ER, Rocha e Silva LF, Lima ES, de Vasconcellos MC, de Andrade Uchoa DE, Filho RB, Pohlit AM.

Molecules. 2013 May 29;18(6):6281-97. doi: 10.3390/molecules18066281.

7.

Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action.

Onyeibor O, Croft SL, Dodson HI, Feiz-Haddad M, Kendrick H, Millington NJ, Parapini S, Phillips RM, Seville S, Shnyder SD, Taramelli D, Wright CW.

J Med Chem. 2005 Apr 7;48(7):2701-9.

8.

Antimalarial activity of some plants traditionally used in Meru district of Kenya.

Muthaura CN, Rukunga GM, Chhabra SC, Omar SA, Guantai AN, Gathirwa JW, Tolo FM, Mwitari PG, Keter LK, Kirira PG, Kimani CW, Mungai GM, Njagi EN.

Phytother Res. 2007 Sep;21(9):860-7.

PMID:
17486688
9.

Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents.

Wright CW, Addae-Kyereme J, Breen AG, Brown JE, Cox MF, Croft SL, Gökçek Y, Kendrick H, Phillips RM, Pollet PL.

J Med Chem. 2001 Sep 13;44(19):3187-94.

PMID:
11543688
10.

In vivo and in vitro antimalarial activity of 4-nerolidylcatechol.

Rocha E Silva LF, Silva Pinto AC, Pohlit AM, Quignard EL, Vieira PP, Tadei WP, Chaves FC, Samonek JF, Lima CA, Costa MR, Alecrim Md, Andrade-Neto VF.

Phytother Res. 2011 Aug;25(8):1181-8. doi: 10.1002/ptr.3424. Epub 2011 Feb 8.

PMID:
21302338
11.

Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum.

Chierrito TP, Aguiar AC, de Andrade IM, Ceravolo IP, Gonçalves RA, de Oliveira AJ, Krettli AU.

Malar J. 2014 Apr 14;13:142. doi: 10.1186/1475-2875-13-142.

12.

Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.

Van Baelen G, Hostyn S, Dhooghe L, Tapolcsányi P, Mátyus P, Lemière G, Dommisse R, Kaiser M, Brun R, Cos P, Maes L, Hajós G, Riedl Z, Nagy I, Maes BU, Pieters L.

Bioorg Med Chem. 2009 Oct 15;17(20):7209-17. doi: 10.1016/j.bmc.2009.08.057. Epub 2009 Sep 3.

PMID:
19781948
13.

Screening of medicinal plants from Reunion Island for antimalarial and cytotoxic activity.

Jonville MC, Kodja H, Humeau L, Fournel J, De Mol P, Cao M, Angenot L, Frédérich M.

J Ethnopharmacol. 2008 Dec 8;120(3):382-6. doi: 10.1016/j.jep.2008.09.005. Epub 2008 Sep 18.

PMID:
18848979
14.

Potential antimalarial activity of indole alkaloids.

Frederich M, Tits M, Angenot L.

Trans R Soc Trop Med Hyg. 2008 Jan;102(1):11-9. Epub 2007 Nov 26. Review.

PMID:
18035385
15.

Evaluation of the antimalarial activity of new compounds against Plasmodium falciparum in vitro, and Plasmodium berghei in vivo.

Tedlaouti F, Gasquet M, Delmas F, Timon-David P, Madadi NE, Vanelle P, Maldonado J.

J Pharm Belg. 1990 Sep-Oct;45(5):306-10.

PMID:
2086754
16.

Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei.

Rajan A, Bagai U.

J Complement Integr Med. 2013 May 7;10. pii: /j/jcim.2013.10.issue-1/jcim-2012-0016/jcim-2012-0016.xml. doi: 10.1515/jcim-2012-0016.

PMID:
23652641
17.

Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog.

Montoia A, Rocha E Silva LF, Torres ZE, Costa DS, Henrique MC, Lima ES, Vasconcellos MC, Souza RC, Costa MR, Grafov A, Grafova I, Eberlin MN, Tadei WP, Amorim RC, Pohlit AM.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. Epub 2014 Apr 28.

PMID:
24813729
18.

The novel oxygenated chalcone, 2,4-dimethoxy-4'-butoxychalcone, exhibits potent activity against human malaria parasite Plasmodium falciparum in vitro and rodent parasites Plasmodium berghei and Plasmodium yoelii in vivo.

Chen M, Brøgger Christensen S, Zhai L, Rasmussen MH, Theander TG, Frøkjaer S, Steffansen B, Davidsen J, Kharazmi A.

J Infect Dis. 1997 Nov;176(5):1327-33.

PMID:
9359735
19.

Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part I: Aspidosperma nitidum (Benth) used as a remedy to treat fever and malaria in the Amazon.

Coutinho JP, Aguiar AC, dos Santos PA, Lima JC, Rocha MG, Zani CL, Alves TM, Santana AE, Pereira Mde M, Krettli AU.

Mem Inst Oswaldo Cruz. 2013 Dec;108(8):974-82. doi: 10.1590/0074-0276130246.

20.

Antimalarial and safety evaluation of Pluchea lanceolata (DC.) Oliv. & Hiern: in-vitro and in-vivo study.

Mohanty S, Srivastava P, Maurya AK, Cheema HS, Shanker K, Dhawan S, Darokar MP, Bawankule DU.

J Ethnopharmacol. 2013 Oct 7;149(3):797-802. doi: 10.1016/j.jep.2013.08.003. Epub 2013 Aug 14.

PMID:
23954323

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