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Insights on FoxN1 biological significance and usages of the "nude" mouse in studies of T-lymphopoiesis.

Zhang Z, Burnley P, Coder B, Su DM.

Int J Biol Sci. 2012;8(8):1156-67. doi: 10.7150/ijbs.5033. Epub 2012 Sep 24. Review.


Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice.

Ruan L, Zhang Z, Mu L, Burnley P, Wang L, Coder B, Zhuge Q, Su DM.

Cell Death Dis. 2014 Oct 9;5:e1457. doi: 10.1038/cddis.2014.432.


Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage.

Corbeaux T, Hess I, Swann JB, Kanzler B, Haas-Assenbaum A, Boehm T.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16613-8. doi: 10.1073/pnas.1004623107. Epub 2010 Sep 7.


FOXN1 in thymus organogenesis and development.

Vaidya HJ, Briones Leon A, Blackburn CC.

Eur J Immunol. 2016 Aug;46(8):1826-37. doi: 10.1002/eji.201545814. Review.


Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells.

Zook EC, Krishack PA, Zhang S, Zeleznik-Le NJ, Firulli AB, Witte PL, Le PT.

Blood. 2011 Nov 24;118(22):5723-31. doi: 10.1182/blood-2011-03-342097. Epub 2011 Sep 9.


Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium.

Guo J, Rahman M, Cheng L, Zhang S, Tvinnereim A, Su DM.

J Mol Med (Berl). 2011 Mar;89(3):263-77. doi: 10.1007/s00109-010-0700-8. Epub 2010 Nov 26.


Learning from nudity: lessons from the nude phenotype.

Mecklenburg L, Tychsen B, Paus R.

Exp Dermatol. 2005 Nov;14(11):797-810. Review.


FOXN1 mutation abrogates prenatal T-cell development in humans.

Vigliano I, Gorrese M, Fusco A, Vitiello L, Amorosi S, Panico L, Ursini MV, Calcagno G, Racioppi L, Del Vecchio L, Pignata C.

J Med Genet. 2011 Jun;48(6):413-6. doi: 10.1136/jmg.2011.089532. Epub 2011 Apr 19.


FOXN1 in organ development and human diseases.

Palamaro L, Romano R, Fusco A, Giardino G, Gallo V, Pignata C.

Int Rev Immunol. 2014 Mar;33(2):83-93. doi: 10.3109/08830185.2013.870171. Epub 2014 Jan 17. Review.


Human clinical phenotype associated with FOXN1 mutations.

Pignata C, Fusco A, Amorosi S.

Adv Exp Med Biol. 2009;665:195-206. Review.


A novel Foxn1eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations.

Barsanti M, Lim JM, Hun ML, Lister N, Wong K, Hammett MV, Lepletier A, Boyd RL, Giudice A, Chidgey AP.

Eur J Immunol. 2017 Feb;47(2):291-304. doi: 10.1002/eji.201646553. Epub 2016 Dec 7.


Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice.

Balciunaite G, Keller MP, Balciunaite E, Piali L, Zuklys S, Mathieu YD, Gill J, Boyd R, Sussman DJ, Holländer GA.

Nat Immunol. 2002 Nov;3(11):1102-8. Epub 2002 Oct 15.


FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus.

Amorosi S, D'Armiento M, Calcagno G, Russo I, Adriani M, Christiano AM, Weiner L, Brissette JL, Pignata C.

Clin Genet. 2008 Apr;73(4):380-4. doi: 10.1111/j.1399-0004.2008.00977.x.


Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.

Zook EC, Zhang S, Gerstein RM, Witte PL, Le PT.

J Immunol. 2013 Dec 1;191(11):5583-93. doi: 10.4049/jimmunol.1202278. Epub 2013 Nov 1.


Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus.

Gordon J, Xiao S, Hughes B 3rd, Su DM, Navarre SP, Condie BG, Manley NR.

BMC Dev Biol. 2007 Jun 18;7:69.


Phospholipase C-delta1 is an essential molecule downstream of Foxn1, the gene responsible for the nude mutation, in normal hair development.

Nakamura Y, Ichinohe M, Hirata M, Matsuura H, Fujiwara T, Igarashi T, Nakahara M, Yamaguchi H, Yasugi S, Takenawa T, Fukami K.

FASEB J. 2008 Mar;22(3):841-9. Epub 2007 Oct 15.


A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation.

Su DM, Navarre S, Oh WJ, Condie BG, Manley NR.

Nat Immunol. 2003 Nov;4(11):1128-35. Epub 2003 Oct 5.


Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution.

Sun L, Guo J, Brown R, Amagai T, Zhao Y, Su DM.

Aging Cell. 2010 Jun;9(3):347-57. doi: 10.1111/j.1474-9726.2010.00559.x. Epub 2010 Mar 12.


Foxn1[Cre] Expression in the Male Germline.

Shi J, Getun I, Torres B, Petrie HT.

PLoS One. 2016 Nov 23;11(11):e0166967. doi: 10.1371/journal.pone.0166967. eCollection 2016.


Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium.

Dooley J, Erickson M, Roelink H, Farr AG.

Dev Dyn. 2005 Aug;233(4):1605-12.

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