Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 145

1.

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity.

Cheng PN, Liu C, Zhao M, Eisenberg D, Nowick JS.

Nat Chem. 2012 Nov;4(11):927-33. doi: 10.1038/nchem.1433. Epub 2012 Sep 9.

2.

Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics.

Liu C, Sawaya MR, Cheng PN, Zheng J, Nowick JS, Eisenberg D.

J Am Chem Soc. 2011 May 4;133(17):6736-44. doi: 10.1021/ja200222n. Epub 2011 Apr 7.

3.

Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide.

Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS.

J Am Chem Soc. 2011 Mar 9;133(9):3144-57. doi: 10.1021/ja110545h. Epub 2011 Feb 14. Erratum in: J Am Chem Soc. 2012 Oct 24;134(42):17832.

4.

Preparation and characterization of neurotoxic tau oligomers.

Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R.

Biochemistry. 2010 Nov 30;49(47):10039-41. doi: 10.1021/bi1016233. Epub 2010 Nov 8.

PMID:
21047142
5.

Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on β-amyloid(1-40) aggregation and toxicity.

Catto M, Arnesano F, Palazzo G, De Stradis A, Calò V, Losacco M, Purgatorio R, Campagna F.

Arch Biochem Biophys. 2014 Oct 15;560:73-82. doi: 10.1016/j.abb.2014.07.015. Epub 2014 Jul 19.

PMID:
25051344
6.

Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide.

Yan LM, Velkova A, Kapurniotu A.

Curr Pharm Des. 2014;20(8):1182-91.

PMID:
23713771
7.

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

Chimon S, Shaibat MA, Jones CR, Calero DC, Aizezi B, Ishii Y.

Nat Struct Mol Biol. 2007 Dec;14(12):1157-64.

PMID:
18059284
8.

Structure-activity relationships of sugar-based peptidomimetics as modulators of amyloid β-peptide early oligomerization and fibrillization.

Kaffy J, Brinet D, Soulier JL, Khemtémourian L, Lequin O, Taverna M, Crousse B, Ongeri S.

Eur J Med Chem. 2014 Oct 30;86:752-8. doi: 10.1016/j.ejmech.2014.09.031. Epub 2014 Sep 10.

PMID:
25238173
9.

αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide.

Dehle FC, Ecroyd H, Musgrave IF, Carver JA.

Cell Stress Chaperones. 2010 Nov;15(6):1013-26. doi: 10.1007/s12192-010-0212-z. Epub 2010 Jul 15.

11.

Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence.

Kellock J, Hopping G, Caughey B, Daggett V.

J Mol Biol. 2016 Jun 5;428(11):2317-28. doi: 10.1016/j.jmb.2016.03.013. Epub 2016 Mar 21.

12.

β-sheet interfering molecules acting against β-amyloid aggregation and fibrillogenesis.

Francioso A, Punzi P, Boffi A, Lori C, Martire S, Giordano C, D'Erme M, Mosca L.

Bioorg Med Chem. 2015 Apr 15;23(8):1671-83. doi: 10.1016/j.bmc.2015.02.041. Epub 2015 Feb 28. Review.

PMID:
25769517
13.

Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides.

Rijkers DT, Höppener JW, Posthuma G, Lips CJ, Liskamp RM.

Chemistry. 2002 Sep 16;8(18):4285-91.

PMID:
12298020
14.

A cyclic KLVFF-derived peptide aggregation inhibitor induces the formation of less-toxic off-pathway amyloid-β oligomers.

Arai T, Sasaki D, Araya T, Sato T, Sohma Y, Kanai M.

Chembiochem. 2014 Nov 24;15(17):2577-83. doi: 10.1002/cbic.201402430. Epub 2014 Sep 26.

PMID:
25262917
15.

Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.

Meredith SC.

Ann N Y Acad Sci. 2005 Dec;1066:181-221. Review.

PMID:
16533927
16.

Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration.

Vieira MN, Forny-Germano L, Saraiva LM, Sebollela A, Martinez AM, Houzel JC, De Felice FG, Ferreira ST.

J Neurochem. 2007 Oct;103(2):736-48. Epub 2007 Aug 28.

18.

EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7710-5. doi: 10.1073/pnas.0910723107. Epub 2010 Apr 12.

19.

Molecular mechanism of β-sheet self-organization at water-hydrophobic interfaces.

Nikolic A, Baud S, Rauscher S, Pomès R.

Proteins. 2011 Jan;79(1):1-22. doi: 10.1002/prot.22854. Epub 2010 Oct 11.

PMID:
20938982
20.

A strategy for designing inhibitors of alpha-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

El-Agnaf OM, Paleologou KE, Greer B, Abogrein AM, King JE, Salem SA, Fullwood NJ, Benson FE, Hewitt R, Ford KJ, Martin FL, Harriott P, Cookson MR, Allsop D.

FASEB J. 2004 Aug;18(11):1315-7. Epub 2004 Jun 4.

PMID:
15180968

Supplemental Content

Support Center