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Items: 1 to 20 of 109

1.

Getting to the core of platinum drug bio-distributions: the penetration of anti-cancer platinum complexes into spheroid tumour models.

Zhang JZ, Bryce NS, Lanzirotti A, Chen CK, Paterson D, de Jonge MD, Howard DL, Hambley TW.

Metallomics. 2012 Nov;4(11):1209-17. doi: 10.1039/c2mt20168b. Epub 2012 Oct 22.

PMID:
23086354
2.

The use of spectroscopic imaging and mapping techniques in the characterisation and study of DLD-1 cell spheroid tumour models.

Zhang JZ, Bryce NS, Siegele R, Carter EA, Paterson D, de Jonge MD, Howard DL, Ryan CG, Hambley TW.

Integr Biol (Camb). 2012 Sep;4(9):1072-80. doi: 10.1039/c2ib20121f. Epub 2012 Aug 2.

PMID:
22858723
3.

Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour models.

Bryce NS, Zhang JZ, Whan RM, Yamamoto N, Hambley TW.

Chem Commun (Camb). 2009 May 21;(19):2673-5. doi: 10.1039/b902415h. Epub 2009 Mar 23.

PMID:
19532917
4.

Elemental tomography of cancer-cell spheroids reveals incomplete uptake of both platinum(II) and platinum(IV) complexes.

Alderden RA, Mellor HR, Modok S, Hall MD, Sutton SR, Newville MG, Callaghan R, Hambley TW.

J Am Chem Soc. 2007 Nov 7;129(44):13400-1. Epub 2007 Oct 12. No abstract available.

PMID:
17929931
5.

Quantitative mapping of platinum and essential trace metal in cisplatin resistant and sensitive human ovarian adenocarcinoma cells.

Ortega R, Moretto P, Fajac A, Benard J, Llabador Y, Simonoff M.

Cell Mol Biol (Noisy-le-grand). 1996 Feb;42(1):77-88.

PMID:
8833669
6.
7.

LA-ICP-MS imaging in multicellular tumor spheroids - a novel tool in the preclinical development of metal-based anticancer drugs.

Theiner S, Schreiber-Brynzak E, Jakupec MA, Galanski M, Koellensperger G, Keppler BK.

Metallomics. 2016 Apr;8(4):398-402. doi: 10.1039/c5mt00276a. Epub 2016 Jan 25.

PMID:
26806253
8.
9.

Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids.

Nicholson KM, Bibby MC, Phillips RM.

Eur J Cancer. 1997 Jul;33(8):1291-8.

PMID:
9301458
10.

Retention of activity by the new generation platinum agent AMD0473 in four human tumour cell lines possessing acquired resistance to oxaliplatin.

Sharp SY, O'Neill CF, Rogers P, Boxall FE, Kelland LR.

Eur J Cancer. 2002 Nov;38(17):2309-15.

PMID:
12441268
11.

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.

Karlsson H, Fryknäs M, Larsson R, Nygren P.

Exp Cell Res. 2012 Aug 1;318(13):1577-85. doi: 10.1016/j.yexcr.2012.03.026. Epub 2012 Apr 2.

PMID:
22487097
12.

Microfluidic device flow field characterization around tumor spheroids with tunable necrosis produced in an optimized off-chip process.

Baye J, Galvin C, Shen AQ.

Biomed Microdevices. 2017 Sep;19(3):59. doi: 10.1007/s10544-017-0200-5.

PMID:
28667400
14.

A multicellular spheroid formation and extraction chip using removable cell trapping barriers.

Jin HJ, Cho YH, Gu JM, Kim J, Oh YS.

Lab Chip. 2011 Jan 7;11(1):115-9. doi: 10.1039/c0lc00134a. Epub 2010 Nov 1.

PMID:
21038070
15.
16.

Multicellular tumor spheroids as an in vivo-like tumor model for three-dimensional imaging of chemotherapeutic and nano material cellular penetration.

Ma HL, Jiang Q, Han S, Wu Y, Cui Tomshine J, Wang D, Gan Y, Zou G, Liang XJ.

Mol Imaging. 2012 Nov-Dec;11(6):487-98.

PMID:
23084249
17.

Nanoscopic tumor tissue distribution of platinum after intraperitoneal administration in a xenograft model of ovarian cancer.

Carlier C, Laforce B, Van Malderen SJM, Gremonprez F, Tucoulou R, Villanova J, De Wever O, Vincze L, Vanhaecke F, Ceelen W.

J Pharm Biomed Anal. 2016 Nov 30;131:256-262. doi: 10.1016/j.jpba.2016.09.004. Epub 2016 Sep 3.

PMID:
27611097
18.

High cytotoxicity of cisplatin nanocapsules in ovarian carcinoma cells depends on uptake by caveolae-mediated endocytosis.

Hamelers IH, Staffhorst RW, Voortman J, de Kruijff B, Reedijk J, van Bergen en Henegouwen PM, de Kroon AI.

Clin Cancer Res. 2009 Feb 15;15(4):1259-68. doi: 10.1158/1078-0432.CCR-08-1702.

19.

Quantitative 3D cell-based assay performed with cellular spheroids and fluorescence microscopy.

Ansari N, Müller S, Stelzer EH, Pampaloni F.

Methods Cell Biol. 2013;113:295-309. doi: 10.1016/B978-0-12-407239-8.00013-6.

PMID:
23317907
20.

Investigations using fluorescent ligands to monitor platinum(IV) reduction and platinum(II) reactions in cancer cells.

New EJ, Duan R, Zhang JZ, Hambley TW.

Dalton Trans. 2009 Apr 28;(16):3092-101. doi: 10.1039/b821603g. Epub 2009 Mar 6.

PMID:
19352538

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