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Items: 1 to 20 of 87

1.

An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo.

Wollish AC, Ferris MT, Blevins LK, Loo YM, Gale M Jr, Heise MT.

Virology. 2013 Jan 20;435(2):269-80. doi: 10.1016/j.virol.2012.09.008. Epub 2012 Oct 17.

2.

Identification of adult mouse neurovirulence determinants of the Sindbis virus strain AR86.

Suthar MS, Shabman R, Madric K, Lambeth C, Heise MT.

J Virol. 2005 Apr;79(7):4219-28.

3.

An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis.

Heise MT, White LJ, Simpson DA, Leonard C, Bernard KA, Meeker RB, Johnston RE.

J Virol. 2003 Jan;77(2):1149-56.

4.
5.

A substitution in nsP1 combined with a double substitution in E2 glycoprotein renders Sindbis-like virus XJ-160 fully neurovirulent for adult mice.

Zhu W, Deng L, Wei Y, Wang H, Wang J, Liang G.

Virus Res. 2015 Jan 22;196:1-4. doi: 10.1016/j.virusres.2014.10.027. Epub 2014 Nov 7.

PMID:
25449361
6.

Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein.

Cruz CC, Suthar MS, Montgomery SA, Shabman R, Simmons J, Johnston RE, Morrison TE, Heise MT.

Virology. 2010 Mar 30;399(1):1-10. doi: 10.1016/j.virol.2009.12.031. Epub 2010 Jan 25.

7.

Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection.

Stoermer Burrack KA, Hawman DW, Jupille HJ, Oko L, Minor M, Shives KD, Gunn BM, Long KM, Morrison TE.

J Virol. 2014 Apr;88(7):3719-32. doi: 10.1128/JVI.02609-13. Epub 2014 Jan 15.

8.

Substitutions of 169Lys and 173Thr in nonstructural protein 1 influence the infectivity and pathogenicity of XJ-160 virus.

Zhu WY, Yang YL, Fu SH, Wang LH, Zai YG, Tang Q, Liang GD.

Arch Virol. 2009;154(2):245-53. doi: 10.1007/s00705-008-0298-0. Epub 2009 Jan 1.

PMID:
19118404
9.

Effects of palmitoylation of replicase protein nsP1 on alphavirus infection.

Ahola T, Kujala P, Tuittila M, Blom T, Laakkonen P, Hinkkanen A, Auvinen P.

J Virol. 2000 Aug;74(15):6725-33.

10.

Both TRIF and IPS-1 adaptor proteins contribute to the cerebral innate immune response against herpes simplex virus 1 infection.

Menasria R, Boivin N, Lebel M, Piret J, Gosselin J, Boivin G.

J Virol. 2013 Jul;87(13):7301-8. doi: 10.1128/JVI.00591-13. Epub 2013 Apr 17.

11.

Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis.

Trgovcich J, Aronson JF, Johnston RE.

Virology. 1996 Oct 1;224(1):73-83.

12.

Effect of E2 envelope glycoprotein cytoplasmic domain mutations on Sindbis virus pathogenesis.

Levine B, Jiang HH, Kleeman L, Yang G.

J Virol. 1996 Feb;70(2):1255-60.

13.

A determinant of Sindbis virus neurovirulence enables efficient disruption of Jak/STAT signaling.

Simmons JD, Wollish AC, Heise MT.

J Virol. 2010 Nov;84(21):11429-39. doi: 10.1128/JVI.00577-10. Epub 2010 Aug 25.

14.

The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice.

Park E, Griffin DE.

Virology. 2009 Jun 5;388(2):305-14. doi: 10.1016/j.virol.2009.03.031. Epub 2009 Apr 23.

15.

Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.

Frolova EI, Fayzulin RZ, Cook SH, Griffin DE, Rice CM, Frolov I.

J Virol. 2002 Nov;76(22):11254-64.

17.

Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses.

Ryman KD, Gardner CL, Burke CW, Meier KC, Thompson JM, Klimstra WB.

J Virol. 2007 Apr;81(7):3563-73. Epub 2007 Jan 10.

18.

Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome.

Klimstra WB, Ryman KD, Bernard KA, Nguyen KB, Biron CA, Johnston RE.

J Virol. 1999 Dec;73(12):10387-98.

19.

TLR signaling controls lethal encephalitis in WNV-infected brain.

Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE.

Brain Res. 2014 Jul 29;1574:84-95. doi: 10.1016/j.brainres.2014.05.049. Epub 2014 Jun 11.

20.

Effects of the nsP2-726 Pro mutation on infectivity and pathogenesis of Sindbis virus derived from a full-length infectious cDNA clone.

Zhu WY, Fu SH, Wang JL, He Y, Tang Q, Liang GD.

Virus Res. 2009 Jun;142(1-2):204-7. doi: 10.1016/j.virusres.2009.01.017. Epub 2009 Feb 7.

PMID:
19428754

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