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Items: 1 to 20 of 132


Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D(2) receptors.

Cho D, Zheng M, Min C, Ma L, Kurose H, Park JH, Kim KM.

Mol Endocrinol. 2010 Mar;24(3):574-86. doi: 10.1210/me.2009-0369. Epub 2010 Feb 16.


G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.

Namkung Y, Dipace C, Javitch JA, Sibley DR.

J Biol Chem. 2009 May 29;284(22):15038-51. doi: 10.1074/jbc.M900388200. Epub 2009 Mar 30.


Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor.

Namkung Y, Sibley DR.

J Biol Chem. 2004 Nov 19;279(47):49533-41. Epub 2004 Sep 3.


Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors.

Min C, Zheng M, Zhang X, Caron MG, Kim KM.

Br J Pharmacol. 2013 Nov;170(5):1112-29. doi: 10.1111/bph.12357.


Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms.

Zhang X, Wang F, Chen X, Chen Y, Ma L.

J Neurochem. 2008 Jul;106(2):781-92. doi: 10.1111/j.1471-4159.2008.05431.x. Epub 2008 Apr 17.


The N-terminal region of the dopamine D2 receptor, a rhodopsin-like GPCR, regulates correct integration into the plasma membrane and endocytic routes.

Cho DI, Min C, Jung KS, Cheong SY, Zheng M, Cheong SJ, Oak MH, Cheong JH, Lee BK, Kim KM.

Br J Pharmacol. 2012 May;166(2):659-75. doi: 10.1111/j.1476-5381.2011.01787.x.


Internalization and sequestration of the human prostacyclin receptor.

Smyth EM, Austin SC, Reilly MP, FitzGerald GA.

J Biol Chem. 2000 Oct 13;275(41):32037-45.


Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins.

Kim KM, Valenzano KJ, Robinson SR, Yao WD, Barak LS, Caron MG.

J Biol Chem. 2001 Oct 5;276(40):37409-14. Epub 2001 Jul 25.


Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism.

Thibault D, Albert PR, Pineyro G, Trudeau LÉ.

J Biol Chem. 2011 Mar 18;286(11):9174-84. doi: 10.1074/jbc.M110.166454. Epub 2011 Jan 13.


Different kinases desensitize the human delta-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists.

Marie N, Aguila B, Hasbi A, Davis A, Jauzac P, Allouche S.

Cell Signal. 2008 Jun;20(6):1209-20. doi: 10.1016/j.cellsig.2008.02.010. Epub 2008 Feb 19.


RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.

Zheng M, Zhang X, Sun N, Min C, Zhang X, Kim KM.

Biochim Biophys Acta. 2016 Aug;1863(8):2072-83. doi: 10.1016/j.bbamcr.2016.05.010. Epub 2016 May 14.


Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes.

Marley A, von Zastrow M.

PLoS One. 2010 Feb 19;5(2):e9325. doi: 10.1371/journal.pone.0009325.


Differential requirements of arrestin-3 and clathrin for ligand-dependent and -independent internalization of human G protein-coupled receptor 40.

Qian J, Wu C, Chen X, Li X, Ying G, Jin L, Ma Q, Li G, Shi Y, Zhang G, Zhou N.

Cell Signal. 2014 Nov;26(11):2412-23. doi: 10.1016/j.cellsig.2014.07.019. Epub 2014 Jul 16.


Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor.

Cho EY, Cho DI, Park JH, Kurose H, Caron MG, Kim KM.

Mol Endocrinol. 2007 Sep;21(9):2242-54. Epub 2007 May 29.


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