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Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5.

Ouyang DY, Xu LH, He XH, Zhang YT, Zeng LH, Cai JY, Ren S.

Autophagy. 2013 Jan;9(1):20-32. doi: 10.4161/auto.22397. Epub 2012 Oct 17.


Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.

Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.

Cancer Res. 2009 Apr 15;69(8):3704-12. doi: 10.1158/0008-5472.CAN-08-4344. Epub 2009 Mar 31.


Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.

Won SJ, Yen CH, Liu HS, Wu SY, Lan SH, Jiang-Shieh YF, Lin CN, Su CL.

J Cell Physiol. 2015 Apr;230(4):930-46. doi: 10.1002/jcp.24825.


Sorafenib-induced defective autophagy promotes cell death by necroptosis.

Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, Lennartsson L, Björklund AC, Zhivotovsky B, Grandér D, Egevad L, Nilsson S, Panaretakis T.

Oncotarget. 2015 Nov 10;6(35):37066-82. doi: 10.18632/oncotarget.5797.


Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells.

Chen ZH, Cao JF, Zhou JS, Liu H, Che LQ, Mizumura K, Li W, Choi AM, Shen HH.

Am J Physiol Lung Cell Mol Physiol. 2014 Jun 1;306(11):L1016-25. doi: 10.1152/ajplung.00268.2013. Epub 2014 Apr 11.


A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.

Chen D, Fan W, Lu Y, Ding X, Chen S, Zhong Q.

Mol Cell. 2012 Mar 9;45(5):629-41. doi: 10.1016/j.molcel.2011.12.036. Epub 2012 Feb 16.


Rab33B and its autophagic Atg5/12/16L1 effector assist in hepatitis B virus naked capsid formation and release.

Döring T, Prange R.

Cell Microbiol. 2015 May;17(5):747-64. doi: 10.1111/cmi.12398. Epub 2015 Jan 24.


Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.

Otomo C, Metlagel Z, Takaesu G, Otomo T.

Nat Struct Mol Biol. 2013 Jan;20(1):59-66. doi: 10.1038/nsmb.2431. Epub 2012 Dec 2.


Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells.

Tai S, Sun Y, Liu N, Ding B, Hsia E, Bhuta S, Thor RK, Damoiseaux R, Liang C, Huang J.

Mol Cancer Ther. 2012 Jun;11(6):1320-31. doi: 10.1158/1535-7163.MCT-11-0954. Epub 2012 Apr 5.


Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation.

Mauthe M, Jacob A, Freiberger S, Hentschel K, Stierhof YD, Codogno P, Proikas-Cezanne T.

Autophagy. 2011 Dec;7(12):1448-61.


HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells.

Wang X, Gao Y, Tan J, Devadas K, Ragupathy V, Takeda K, Zhao J, Hewlett I.

Cell Signal. 2012 Jul;24(7):1414-9. doi: 10.1016/j.cellsig.2012.02.016. Epub 2012 Mar 2.


The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.

Boyer-Guittaut M, Poillet L, Liang Q, Bôle-Richard E, Ouyang X, Benavides GA, Chakrama FZ, Fraichard A, Darley-Usmar VM, Despouy G, Jouvenot M, Delage-Mourroux R, Zhang J.

Autophagy. 2014 Jun;10(6):986-1003. doi: 10.4161/auto.28390.


Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.

Tang Y, Chen Y, Jiang H, Nie D.

Cell Death Differ. 2011 Apr;18(4):602-18. doi: 10.1038/cdd.2010.117. Epub 2010 Oct 8.


Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin).

Singh K, Sharma A, Mir MC, Drazba JA, Heston WD, Magi-Galluzzi C, Hansel D, Rubin BP, Klein EA, Almasan A.

Mol Cancer. 2014 Mar 23;13:70. doi: 10.1186/1476-4598-13-70.


Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.

Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden AI, Lipinski MM.

Autophagy. 2014;10(12):2208-22. doi: 10.4161/15548627.2014.981787.


Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity.

Takanezawa Y, Nakamura R, Sone Y, Uraguchi S, Kiyono M.

Toxicol Lett. 2016 Nov 16;262:135-141. doi: 10.1016/j.toxlet.2016.09.007. Epub 2016 Sep 22.


Autophagy impairment induces premature senescence in primary human fibroblasts.

Kang HT, Lee KB, Kim SY, Choi HR, Park SC.

PLoS One. 2011;6(8):e23367. doi: 10.1371/journal.pone.0023367. Epub 2011 Aug 8.


Phenethyl caffeate benzoxanthene lignan is a derivative of caffeic acid phenethyl ester that induces bystander autophagy in WiDr cells.

Vijayakurup V, Spatafora C, Tringali C, Jayakrishnan PC, Srinivas P, Gopala S.

Mol Biol Rep. 2014 Jan;41(1):85-94. doi: 10.1007/s11033-013-2840-8. Epub 2013 Nov 5.


Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.

Zha QB, Zhang XY, Lin QR, Xu LH, Zhao GX, Pan H, Zhou D, Ouyang DY, Liu ZH, He XH.

PLoS One. 2015 May 13;10(5):e0124355. doi: 10.1371/journal.pone.0124355. eCollection 2015.


Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells.

Zhu K, Dunner K Jr, McConkey DJ.

Oncogene. 2010 Jan 21;29(3):451-62. doi: 10.1038/onc.2009.343. Epub 2009 Nov 2.

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