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Items: 1 to 20 of 94

1.

Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthase.

Winter JM, Sato M, Sugimoto S, Chiou G, Garg NK, Tang Y, Watanabe K.

J Am Chem Soc. 2012 Oct 31;134(43):17900-3. doi: 10.1021/ja3090498. Epub 2012 Oct 19.

2.

Combinatorial Generation of Chemical Diversity by Redox Enzymes in Chaetoviridin Biosynthesis.

Sato M, Winter JM, Kishimoto S, Noguchi H, Tang Y, Watanabe K.

Org Lett. 2016 Mar 18;18(6):1446-9. doi: 10.1021/acs.orglett.6b00380. Epub 2016 Mar 9.

3.

Absolute stereostructures of chaetomugilins G and H produced by a marine-fish-derived Chaetomium species.

Yamada T, Yasuhide M, Shigeta H, Numata A, Tanaka R.

J Antibiot (Tokyo). 2009 Jul;62(7):353-7. doi: 10.1038/ja.2009.39. Epub 2009 May 22.

PMID:
19461670
4.

Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis.

Winter JM, Cascio D, Dietrich D, Sato M, Watanabe K, Sawaya MR, Vederas JC, Tang Y.

J Am Chem Soc. 2015 Aug 12;137(31):9885-93. doi: 10.1021/jacs.5b04520. Epub 2015 Jul 30.

5.
6.

Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain.

Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y.

Org Lett. 2013 Jul 19;15(14):3774-7. doi: 10.1021/ol401723h. Epub 2013 Jul 9.

7.

Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba.

Qin JC, Zhang YM, Gao JM, Bai MS, Yang SX, Laatsch H, Zhang AL.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1572-4. doi: 10.1016/j.bmcl.2009.02.025. Epub 2009 Feb 11.

PMID:
19246197
8.

Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment.

McMullin DR, Sumarah MW, Miller JD.

Mycotoxin Res. 2013 Feb;29(1):47-54. doi: 10.1007/s12550-012-0144-9. Epub 2012 Oct 17.

PMID:
23334724
9.

A PKS gene, pks-1, is involved in chaetoglobosin biosynthesis, pigmentation and sporulation in Chaetomium globosum.

Hu Y, Hao X, Lou J, Zhang P, Pan J, Zhu X.

Sci China Life Sci. 2012 Dec;55(12):1100-8. doi: 10.1007/s11427-012-4409-5. Epub 2012 Dec 12.

PMID:
23233225
10.

A single module type I polyketide synthase directs de novo macrolactone biogenesis during galbonolide biosynthesis in Streptomyces galbus.

Kim HJ, Karki S, Kwon SY, Park SH, Nahm BH, Kim YK, Kwon HJ.

J Biol Chem. 2014 Dec 12;289(50):34557-68. doi: 10.1074/jbc.M114.602334. Epub 2014 Oct 21.

11.

Identification of the post-polyketide synthase modification enzymes for fostriecin biosynthesis in Streptomyces pulveraceus.

Liu XJ, Kong RX, Niu MS, Qiu RG, Tang L.

J Nat Prod. 2013 Apr 26;76(4):524-9. doi: 10.1021/np300667r. Epub 2013 Apr 15.

PMID:
23586868
12.

Biosynthetic Pathway of the Reduced Polyketide Product Citreoviridin in Aspergillus terreus var. aureus Revealed by Heterologous Expression in Aspergillus nidulans.

Lin TS, Chiang YM, Wang CC.

Org Lett. 2016 Mar 18;18(6):1366-9. doi: 10.1021/acs.orglett.6b00299. Epub 2016 Mar 8.

PMID:
26954888
13.

New azaphilones and chlorinated phenolic glycosides from Chaetomium elatum with caspase-3 inhibitory activity.

Chen GD, Li YJ, Gao H, Chen Y, Li XX, Li J, Guo LD, Cen YZ, Yao XS.

Planta Med. 2012 Oct;78(15):1683-9. doi: 10.1055/s-0032-1315211. Epub 2012 Aug 13.

PMID:
22890540
14.

Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function.

Newman AG, Vagstad AL, Belecki K, Scheerer JR, Townsend CA.

Chem Commun (Camb). 2012 Dec 14;48(96):11772-4. doi: 10.1039/c2cc36010a. Epub 2012 Oct 29.

15.

Non-colinear polyketide biosynthesis in the aureothin and neoaureothin pathways: an evolutionary perspective.

Traitcheva N, Jenke-Kodama H, He J, Dittmann E, Hertweck C.

Chembiochem. 2007 Oct 15;8(15):1841-9.

PMID:
17763486
16.

Evolution of metabolic diversity in polyketide-derived pyrones: using the non-colinear aureothin assembly line as a model system.

Busch B, Hertweck C.

Phytochemistry. 2009 Oct-Nov;70(15-16):1833-40. doi: 10.1016/j.phytochem.2009.05.022. Epub 2009 Aug 3. Review.

PMID:
19651421
17.

Salinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase.

Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS.

Chembiochem. 2015 Jul 6;16(10):1443-7. doi: 10.1002/cbic.201500177. Epub 2015 May 15.

18.

Advances in polyketide synthase structure and function.

Van Lanen SG, Shen B.

Curr Opin Drug Discov Devel. 2008 Mar;11(2):186-95. Review.

PMID:
18283606
19.

Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation.

Zabala AO, Xu W, Chooi YH, Tang Y.

Chem Biol. 2012 Aug 24;19(8):1049-59. doi: 10.1016/j.chembiol.2012.07.004.

20.

Rational design of modular polyketide synthases: morphing the aureothin pathway into a luteoreticulin assembly line.

Sugimoto Y, Ding L, Ishida K, Hertweck C.

Angew Chem Int Ed Engl. 2014 Feb 3;53(6):1560-4. doi: 10.1002/anie.201308176. Epub 2014 Jan 8.

PMID:
24402879

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