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Items: 1 to 20 of 120

1.

Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases.

Pardo B, Aguilera A.

PLoS Genet. 2012 Sep;8(9):e1002979. doi: 10.1371/journal.pgen.1002979. Epub 2012 Sep 27.

2.

Template switching during break-induced replication is promoted by the Mph1 helicase in Saccharomyces cerevisiae.

Stafa A, Donnianni RA, Timashev LA, Lam AF, Symington LS.

Genetics. 2014 Apr;196(4):1017-28. doi: 10.1534/genetics.114.162297. Epub 2014 Feb 4.

3.

Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange.

Muñoz-Galván S, Tous C, Blanco MG, Schwartz EK, Ehmsen KT, West SC, Heyer WD, Aguilera A.

Mol Cell Biol. 2012 May;32(9):1592-603. doi: 10.1128/MCB.00111-12. Epub 2012 Feb 21.

4.

The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats.

Mazón G, Lam AF, Ho CK, Kupiec M, Symington LS.

Nat Struct Mol Biol. 2012 Sep;19(9):964-71. doi: 10.1038/nsmb.2359. Epub 2012 Aug 12.

5.

Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae.

Blanco MG, Matos J, Rass U, Ip SC, West SC.

DNA Repair (Amst). 2010 Apr 4;9(4):394-402. doi: 10.1016/j.dnarep.2009.12.017. Epub 2010 Jan 27.

PMID:
20106725
6.

Template switching during break-induced replication.

Smith CE, Llorente B, Symington LS.

Nature. 2007 May 3;447(7140):102-5. Epub 2007 Apr 4.

PMID:
17410126
7.

Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.

Ho CK, Mazón G, Lam AF, Symington LS.

Mol Cell. 2010 Dec 22;40(6):988-1000. doi: 10.1016/j.molcel.2010.11.016.

8.

RAD51-dependent break-induced replication in yeast.

Davis AP, Symington LS.

Mol Cell Biol. 2004 Mar;24(6):2344-51.

9.

Chromosome aberrations resulting from double-strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements are independent of Mre11p and Sae2p.

Casper AM, Greenwell PW, Tang W, Petes TD.

Genetics. 2009 Oct;183(2):423-39, 1SI-26SI. doi: 10.1534/genetics.109.106385. Epub 2009 Jul 27.

10.

Mph1 and Mus81-Mms4 prevent aberrant processing of mitotic recombination intermediates.

Mazón G, Symington LS.

Mol Cell. 2013 Oct 10;52(1):63-74. doi: 10.1016/j.molcel.2013.09.007.

11.

Mutants defective in Rad1-Rad10-Slx4 exhibit a unique pattern of viability during mating-type switching in Saccharomyces cerevisiae.

Lyndaker AM, Goldfarb T, Alani E.

Genetics. 2008 Aug;179(4):1807-21. doi: 10.1534/genetics.108.090654. Epub 2008 Jun 24.

12.

Overlapping roles for Yen1 and Mus81 in cellular Holliday junction processing.

Tay YD, Wu L.

J Biol Chem. 2010 Apr 9;285(15):11427-32. doi: 10.1074/jbc.M110.108399. Epub 2010 Feb 22.

13.

Migrating bubble during break-induced replication drives conservative DNA synthesis.

Saini N, Ramakrishnan S, Elango R, Ayyar S, Zhang Y, Deem A, Ira G, Haber JE, Lobachev KS, Malkova A.

Nature. 2013 Oct 17;502(7471):389-92. doi: 10.1038/nature12584. Epub 2013 Sep 11.

14.

DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.

Mayle R, Campbell IM, Beck CR, Yu Y, Wilson M, Shaw CA, Bjergbaek L, Lupski JR, Ira G.

Science. 2015 Aug 14;349(6249):742-7. doi: 10.1126/science.aaa8391.

15.

Aberrant double-strand break repair resulting in half crossovers in mutants defective for Rad51 or the DNA polymerase delta complex.

Smith CE, Lam AF, Symington LS.

Mol Cell Biol. 2009 Mar;29(6):1432-41. doi: 10.1128/MCB.01469-08. Epub 2009 Jan 12.

16.

A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms.

Moriel-Carretero M, Aguilera A.

Mol Cell. 2010 Mar 12;37(5):690-701. doi: 10.1016/j.molcel.2010.02.008.

17.

Chromosome rearrangements via template switching between diverged repeated sequences.

Anand RP, Tsaponina O, Greenwell PW, Lee CS, Du W, Petes TD, Haber JE.

Genes Dev. 2014 Nov 1;28(21):2394-406. doi: 10.1101/gad.250258.114.

18.

RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion.

Malkova A, Naylor ML, Yamaguchi M, Ira G, Haber JE.

Mol Cell Biol. 2005 Feb;25(3):933-44.

19.

Chromosomal translocations caused by either pol32-dependent or pol32-independent triparental break-induced replication.

Ruiz JF, Gómez-González B, Aguilera A.

Mol Cell Biol. 2009 Oct;29(20):5441-54. doi: 10.1128/MCB.00256-09. Epub 2009 Aug 3.

20.

Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replication.

Marrero VA, Symington LS.

PLoS Genet. 2010 Jul 8;6(7):e1001007. doi: 10.1371/journal.pgen.1001007.

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