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Items: 1 to 20 of 141

1.

The Helicobacter pylori protein HspB interferes with Nrf2/Keap1 pathway altering the antioxidant response of Ags cells.

Buommino E, Donnarumma G, Manente L, De Filippis A, Silvestri F, Iaquinto S, Tufano MA, De Luca A.

Helicobacter. 2012 Dec;17(6):417-25. doi: 10.1111/j.1523-5378.2012.00973.x. Epub 2012 Jul 11.

PMID:
23066931
2.

Evaluation of the antioxidant properties of carexanes in AGS cells transfected with the Helicobacter pylori's protein HspB.

Buommino E, D'Abrosca B, Donnarumma G, Parisi A, Scognamiglio M, Fiorentino A, De Luca A.

Microb Pathog. 2017 Jul;108:71-77. doi: 10.1016/j.micpath.2017.05.007. Epub 2017 May 4.

PMID:
28479510
3.

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.

J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.

5.

miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells.

Eades G, Yang M, Yao Y, Zhang Y, Zhou Q.

J Biol Chem. 2011 Nov 25;286(47):40725-33. doi: 10.1074/jbc.M111.275495. Epub 2011 Sep 16.

6.

Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.

Yang SP, Yang XZ, Cao GP.

Mol Med Rep. 2015 Jul;12(1):1145-50. doi: 10.3892/mmr.2015.3490. Epub 2015 Mar 13.

PMID:
25776802
7.

Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes.

Zhao R, Hou Y, Zhang Q, Woods CG, Xue P, Fu J, Yarborough K, Guan D, Andersen ME, Pi J.

Environ Health Perspect. 2012 Apr;120(4):583-9. doi: 10.1289/ehp.1104580. Epub 2012 Jan 3.

8.

Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy.

Zhong Q, Mishra M, Kowluru RA.

Invest Ophthalmol Vis Sci. 2013 Jun 6;54(6):3941-8. doi: 10.1167/iovs.13-11598.

9.

Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure.

Kim HJ, Vaziri ND.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F662-71. doi: 10.1152/ajprenal.00421.2009. Epub 2009 Dec 9.

10.

The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO).

Rinaldi Tosi ME, Bocanegra V, Manucha W, Gil Lorenzo A, Vallés PG.

Cell Stress Chaperones. 2011 Jan;16(1):57-68. doi: 10.1007/s12192-010-0221-y. Epub 2010 Aug 24.

11.

Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation.

Kim S, Lee HG, Park SA, Kundu JK, Keum YS, Cha YN, Na HK, Surh YJ.

PLoS One. 2014 Jan 28;9(1):e85984. doi: 10.1371/journal.pone.0085984. eCollection 2014.

12.

Time course of Keap1-Nrf2 pathway expression after experimental intracerebral haemorrhage: correlation with brain oedema and neurological deficit.

Shang H, Yang D, Zhang W, Li T, Ren X, Wang X, Zhao W.

Free Radic Res. 2013 May;47(5):368-75. doi: 10.3109/10715762.2013.778403. Epub 2013 Mar 21.

PMID:
23438812
13.

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.

Nguyen T, Sherratt PJ, Nioi P, Yang CS, Pickett CB.

J Biol Chem. 2005 Sep 16;280(37):32485-92. Epub 2005 Jul 6.

14.

Molecular mechanisms of Nrf2-mediated antioxidant response.

Li W, Kong AN.

Mol Carcinog. 2009 Feb;48(2):91-104. doi: 10.1002/mc.20465. Review.

15.

Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.

Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.

Arch Biochem Biophys. 2010 Sep 1;501(1):142-50. doi: 10.1016/j.abb.2010.06.011. Epub 2010 Jun 15.

PMID:
20558128
16.

Nrf2-Keap1 antioxidant defense and cell survival signaling are upregulated by 17β-estradiol in homocysteine-treated dopaminergic SH-SY5Y cells.

Chen CS, Tseng YT, Hsu YY, Lo YC.

Neuroendocrinology. 2013;97(3):232-41. doi: 10.1159/000342692. Epub 2012 Nov 2.

PMID:
22948038
17.

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.

Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):27-36. doi: 10.1016/j.taap.2009.12.012. Epub 2009 Dec 21.

PMID:
20026152
18.

MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression.

Kabaria S, Choi DC, Chaudhuri AD, Jain MR, Li H, Junn E.

Free Radic Biol Med. 2015 Dec;89:548-56. doi: 10.1016/j.freeradbiomed.2015.09.010. Epub 2015 Oct 8.

19.

Alleviation of cadmium-induced oxidative stress by trehalose via inhibiting the Nrf2-Keap1 signaling pathway in primary rat proximal tubular cells.

Wang XY, Wang ZY, Zhu YS, Zhu SM, Fan RF, Wang L.

J Biochem Mol Toxicol. 2018 Jan;32(1). doi: 10.1002/jbt.22011. Epub 2017 Nov 15.

PMID:
29140578
20.

Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.

Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S.

Am J Respir Cell Mol Biol. 2010 May;42(5):524-36. doi: 10.1165/rcmb.2009-0054OC. Epub 2009 Jun 11.

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