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Items: 1 to 20 of 84

1.
2.

Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.

Fujii S, Ito K, Ito Y, Ochiai A.

J Biol Chem. 2008 Jun 20;283(25):17324-32. doi: 10.1074/jbc.M800224200. Epub 2008 Apr 22.

3.

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.

Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP.

Nat Genet. 2008 Jun;40(6):741-50. doi: 10.1038/ng.159. Epub 2008 May 18.

PMID:
18488029
4.

Identification of coexistence of DNA methylation and H3K27me3 specifically in cancer cells as a promising target for epigenetic therapy.

Takeshima H, Wakabayashi M, Hattori N, Yamashita S, Ushijima T.

Carcinogenesis. 2015 Feb;36(2):192-201. doi: 10.1093/carcin/bgu238. Epub 2014 Dec 4.

PMID:
25477340
5.

Epigenetic regulation of cell adhesion and communication by enhancer of zeste homolog 2 in human endothelial cells.

Dreger H, Ludwig A, Weller A, Stangl V, Baumann G, Meiners S, Stangl K.

Hypertension. 2012 Nov;60(5):1176-83. doi: 10.1161/HYPERTENSIONAHA.112.191098. Epub 2012 Sep 10.

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The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.

Mozzetta C, Pontis J, Fritsch L, Robin P, Portoso M, Proux C, Margueron R, Ait-Si-Ali S.

Mol Cell. 2014 Jan 23;53(2):277-89. doi: 10.1016/j.molcel.2013.12.005. Epub 2014 Jan 2.

8.
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[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].

Yang N, Li Z.

Zhonghua Yi Xue Za Zhi. 2008 Aug 19;88(32):2295-8. Chinese.

PMID:
19087683
11.

Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells.

Murata T, Kondo Y, Sugimoto A, Kawashima D, Saito S, Isomura H, Kanda T, Tsurumi T.

J Virol. 2012 May;86(9):4752-61. doi: 10.1128/JVI.06768-11. Epub 2012 Feb 22.

12.

Epigenetic regulation of CIITA expression in human T-cells.

van Eggermond MC, Boom DR, Klous P, Schooten E, Marquez VE, Wierda RJ, Holling TM, van den Elsen PJ.

Biochem Pharmacol. 2011 Nov 15;82(10):1430-7. doi: 10.1016/j.bcp.2011.05.026. Epub 2011 Jun 2.

PMID:
21664896
13.

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.

Fiskus W, Wang Y, Sreekumar A, Buckley KM, Shi H, Jillella A, Ustun C, Rao R, Fernandez P, Chen J, Balusu R, Koul S, Atadja P, Marquez VE, Bhalla KN.

Blood. 2009 Sep 24;114(13):2733-43. doi: 10.1182/blood-2009-03-213496. Epub 2009 Jul 28.

14.

Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.

Yun J, Song SH, Park J, Kim HP, Yoon YK, Lee KH, Han SW, Oh DY, Im SA, Bang YJ, Kim TY.

Lab Invest. 2012 Jul;92(7):1033-44. doi: 10.1038/labinvest.2012.61. Epub 2012 Apr 16. Erratum in: Lab Invest. 2013 Oct;93(10):1165.

15.

Histone methyltransferase enhancer of zeste homolog 2 regulates Schwann cell differentiation.

Heinen A, Tzekova N, Graffmann N, Torres KJ, Uhrberg M, Hartung HP, Küry P.

Glia. 2012 Nov;60(11):1696-708. doi: 10.1002/glia.22388. Epub 2012 Jul 20.

PMID:
22821416
16.

Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.

Zhang C, Li H, Zhou G, Zhang Q, Zhang T, Li J, Zhang J, Hou J, Liew CT, Yin D.

J Pathol. 2007 Jun;212(2):134-42.

PMID:
17471463
17.

Gestational diabetes mellitus impairs fetal endothelial cell functions through a mechanism involving microRNA-101 and histone methyltransferase enhancer of zester homolog-2.

Floris I, Descamps B, Vardeu A, Mitić T, Posadino AM, Shantikumar S, Sala-Newby G, Capobianco G, Mangialardi G, Howard L, Dessole S, Urrutia R, Pintus G, Emanueli C.

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):664-74. doi: 10.1161/ATVBAHA.114.304730. Epub 2015 Jan 22.

18.

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

Kirmizis A, Bartley SM, Kuzmichev A, Margueron R, Reinberg D, Green R, Farnham PJ.

Genes Dev. 2004 Jul 1;18(13):1592-605.

19.

[Histone H3 lysine 9 methylation is associated with the expression of hMLH1 and DNA methylation in gastric cancer cells].

Meng CF, Zhu XJ, Peng G.

Zhonghua Yi Xue Za Zhi. 2008 Sep 16;88(35):2490-3. Chinese.

PMID:
19080631
20.

Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.

Zhang C, Li H, Wang Y, Liu W, Zhang Q, Zhang T, Zhang X, Han B, Zhou G.

J Hepatol. 2010 Nov;53(5):889-95. doi: 10.1016/j.jhep.2010.05.012. Epub 2010 Jul 14.

PMID:
20675009

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