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Items: 1 to 20 of 98

1.

Canonical and atypical E2Fs regulate the mammalian endocycle.

Chen HZ, Ouseph MM, Li J, Pécot T, Chokshi V, Kent L, Bae S, Byrne M, Duran C, Comstock G, Trikha P, Mair M, Senapati S, Martin CK, Gandhi S, Wilson N, Liu B, Huang YW, Thompson JC, Raman S, Singh S, Leone M, Machiraju R, Huang K, Mo X, Fernandez S, Kalaszczynska I, Wolgemuth DJ, Sicinski P, Huang T, Jin V, Leone G.

Nat Cell Biol. 2012 Nov;14(11):1192-202. doi: 10.1038/ncb2595. Epub 2012 Oct 14.

2.

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.

Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G.

Nature. 2009 Dec 17;462(7275):930-4. doi: 10.1038/nature08677.

3.

Division and apoptosis of E2f-deficient retinal progenitors.

Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R.

Nature. 2009 Dec 17;462(7275):925-9. doi: 10.1038/nature08544.

4.

Atypical E2F repressors and activators coordinate placental development.

Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G.

Dev Cell. 2012 Apr 17;22(4):849-62. doi: 10.1016/j.devcel.2012.01.013.

5.

E2F8 is essential for polyploidization in mammalian cells.

Pandit SK, Westendorp B, Nantasanti S, van Liere E, Tooten PC, Cornelissen PW, Toussaint MJ, Lamers WH, de Bruin A.

Nat Cell Biol. 2012 Nov;14(11):1181-91. doi: 10.1038/ncb2585. Epub 2012 Oct 14.

PMID:
23064264
6.

Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.

Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G.

Nat Cell Biol. 2015 Aug;17(8):1036-48. doi: 10.1038/ncb3210. Epub 2015 Jul 20.

7.

Mouse development with a single E2F activator.

Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, Feria-Arias E, Timmers C, Opavska J, de Bruin A, Chong JL, Trikha P, Fernandez SA, Stromberg P, Rosol TJ, Leone G.

Nature. 2008 Aug 28;454(7208):1137-41. doi: 10.1038/nature07066. Epub 2008 Jun 25.

8.

p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.

Truscott M, Harada R, Vadnais C, Robert F, Nepveu A.

Mol Cell Biol. 2008 May;28(10):3127-38. doi: 10.1128/MCB.02089-07. Epub 2008 Mar 17.

9.

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.

Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G.

J Biol Chem. 2005 May 6;280(18):18211-20. Epub 2005 Feb 18.

10.

Distinctions in the specificity of E2F function revealed by gene expression signatures.

Black EP, Hallstrom T, Dressman HK, West M, Nevins JR.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15948-53. Epub 2005 Oct 25.

11.

E2f1-3 are critical for myeloid development.

Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G.

J Biol Chem. 2011 Feb 11;286(6):4783-95. doi: 10.1074/jbc.M110.182733. Epub 2010 Nov 28.

12.

Transcription factors E2F1 and E2F3 are expressed in placenta but do not regulate MMP14.

Kaitu'u-Lino TJ, Hastie R, Cannon P, Nguyen H, Lee S, Hannan NJ, Tong S.

Placenta. 2015 Aug;36(8):932-7. doi: 10.1016/j.placenta.2015.06.007. Epub 2015 Jun 23.

PMID:
26145228
13.

Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression.

Liu B, Shats I, Angus SP, Gatza ML, Nevins JR.

J Biol Chem. 2013 Aug 23;288(34):24581-9. doi: 10.1074/jbc.M113.467506. Epub 2013 Jul 13.

14.

The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer.

Hollern DP, Honeysett J, Cardiff RD, Andrechek ER.

Mol Cell Biol. 2014 Sep;34(17):3229-43. doi: 10.1128/MCB.00737-14. Epub 2014 Jun 16.

15.

E2Fs link the control of G1/S and G2/M transcription.

Zhu W, Giangrande PH, Nevins JR.

EMBO J. 2004 Nov 24;23(23):4615-26. Epub 2004 Oct 28.

16.

The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors.

Shen Q, Uray IP, Li Y, Krisko TI, Strecker TE, Kim HT, Brown PH.

Oncogene. 2008 Jan 10;27(3):366-77. Epub 2007 Jul 16.

PMID:
17637753
17.

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.

Schlisio S, Halperin T, Vidal M, Nevins JR.

EMBO J. 2002 Nov 1;21(21):5775-86.

18.
19.

E2f8 mediates tumor suppression in postnatal liver development.

Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G.

J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25.

20.

E2F2 represses cell cycle regulators to maintain quiescence.

Infante A, Laresgoiti U, Fernández-Rueda J, Fullaondo A, Galán J, Díaz-Uriarte R, Malumbres M, Field SJ, Zubiaga AM.

Cell Cycle. 2008 Dec 15;7(24):3915-27. Epub 2008 Dec 10.

PMID:
19066456

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