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Items: 1 to 20 of 315

1.

β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice.

Wei G, Chen YB, Chen DF, Lai XP, Liu DH, Deng RD, Zhou JH, Zhang SX, Li YW, Lii H, Liu LF, Wang Q, Nie H.

J Alzheimers Dis. 2013;33(3):863-80. doi: 10.3233/JAD-2012-120865.

PMID:
23064259
2.

L-3-n-butylphthalide reduces tau phosphorylation and improves cognitive deficits in AβPP/PS1-Alzheimer's transgenic mice.

Peng Y, Hu Y, Xu S, Li P, Li J, Lu L, Yang H, Feng N, Wang L, Wang X.

J Alzheimers Dis. 2012;29(2):379-91. doi: 10.3233/JAD-2011-111577.

PMID:
22233765
3.

The alterations of Ca2+/calmodulin/CaMKII/CaV1.2 signaling in experimental models of Alzheimer's disease and vascular dementia.

Min D, Guo F, Zhu S, Xu X, Mao X, Cao Y, Lv X, Gao Q, Wang L, Chen T, Shaw C, Hao L, Cai J.

Neurosci Lett. 2013 Mar 22;538:60-5. doi: 10.1016/j.neulet.2013.02.001. Epub 2013 Feb 8.

PMID:
23403102
4.

The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.

Li N, Liu GT.

Acta Pharmacol Sin. 2010 Mar;31(3):265-72. doi: 10.1038/aps.2010.3. Epub 2010 Feb 15.

5.

Lamotrigine Reduces β-Site AβPP-Cleaving Enzyme 1 Protein Levels Through Induction of Autophagy.

Wu H, Lu MH, Wang W, Zhang MY, Zhu QQ, Xia YY, Xu RX, Yang Y, Chen LH, Ma QH.

J Alzheimers Dis. 2015;46(4):863-76. doi: 10.3233/JAD-143162.

PMID:
25854934
6.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

7.

Beta-asarone protection against beta-amyloid-induced neurotoxicity in PC12 cells via JNK signaling and modulation of Bcl-2 family proteins.

Li C, Xing G, Dong M, Zhou L, Li J, Wang G, Zou D, Wang R, Liu J, Niu Y.

Eur J Pharmacol. 2010 Jun 10;635(1-3):96-102. doi: 10.1016/j.ejphar.2010.03.013. Epub 2010 Mar 20.

PMID:
20307525
8.

A novel drug candidate for Alzheimer's disease treatment: gx-50 derived from Zanthoxylum bungeanum.

Tang M, Wang Z, Zhou Y, Xu W, Li S, Wang L, Wei D, Qiao Z.

J Alzheimers Dis. 2013;34(1):203-13. doi: 10.3233/JAD-121831.

PMID:
23186988
9.

An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.

Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, Friesenhahn M, Ho C, Paul R, Pfeifer A, Muhs A, Watts RJ.

J Neurosci. 2012 Jul 11;32(28):9677-89. doi: 10.1523/JNEUROSCI.4742-11.2012.

10.

Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.

Baglietto-Vargas D, Moreno-Gonzalez I, Sanchez-Varo R, Jimenez S, Trujillo-Estrada L, Sanchez-Mejias E, Torres M, Romero-Acebal M, Ruano D, Vizuete M, Vitorica J, Gutierrez A.

J Alzheimers Dis. 2010;21(1):119-32. doi: 10.3233/JAD-2010-100066.

PMID:
20413859
11.

Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats.

Geng Y, Li C, Liu J, Xing G, Zhou L, Dong M, Li X, Niu Y.

Biol Pharm Bull. 2010;33(5):836-43.

12.

Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.

Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.

J Neurosci Res. 2002 Aug 15;69(4):530-9.

PMID:
12210846
13.

Beta-asarone attenuates neuronal apoptosis induced by Beta amyloid in rat hippocampus.

Liu J, Li C, Xing G, Zhou L, Dong M, Geng Y, Li X, Li J, Wang G, Zou D, Niu Y.

Yakugaku Zasshi. 2010 May;130(5):737-46.

14.

Clioquinol reduces zinc accumulation in neuritic plaques and inhibits the amyloidogenic pathway in AβPP/PS1 transgenic mouse brain.

Wang T, Wang CY, Shan ZY, Teng WP, Wang ZY.

J Alzheimers Dis. 2012;29(3):549-59. doi: 10.3233/JAD-2011-111874.

PMID:
22269164
15.

Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease.

Pérez-González R, Antequera D, Vargas T, Spuch C, Bolós M, Carro E.

J Alzheimers Dis. 2011;24 Suppl 2:17-25. doi: 10.3233/JAD-2011-102070.

PMID:
21335656
16.
17.

GSK-3/CREB pathway involved in the gx-50's effect on Alzheimer's disease.

Tang M, Shi S, Guo Y, Xu W, Wang L, Chen Y, Wang Z, Qiao Z.

Neuropharmacology. 2014 Jun;81:256-66. doi: 10.1016/j.neuropharm.2014.02.008. Epub 2014 Feb 21.

PMID:
24565641
18.

Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway.

Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO.

Eur J Pharmacol. 2011 Dec 15;672(1-3):45-55. doi: 10.1016/j.ejphar.2011.09.177. Epub 2011 Sep 29.

PMID:
21978835
19.

Lesion-induced hippocampal plasticity in transgenic Alzheimer's disease mouse models: influences of age, genotype, and estrogen.

Kadish I, van Groen T.

J Alzheimers Dis. 2009;18(2):429-45. doi: 10.3233/JAD-2009-1157.

PMID:
19584452
20.

β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors.

Shrivastava AN, Kowalewski JM, Renner M, Bousset L, Koulakoff A, Melki R, Giaume C, Triller A.

Glia. 2013 Oct;61(10):1673-86. doi: 10.1002/glia.22548. Epub 2013 Aug 6.

PMID:
23922225
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