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Items: 1 to 20 of 110

1.

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D, Assi SA, Lie-A-Ling M, Noailles L, Vijayabaskar MS, Wu M, Tenen DG, Westhead DR, Kouskoff V, Lacaud G, Göttgens B, Bonifer C.

EMBO J. 2012 Nov 14;31(22):4318-33. doi: 10.1038/emboj.2012.275. Epub 2012 Oct 12.

2.

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages.

Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, Tapscott SJ, Brand M.

EMBO J. 2011 Feb 2;30(3):494-509. doi: 10.1038/emboj.2010.342. Epub 2010 Dec 21.

3.

SCL/TAL1 in Hematopoiesis and Cellular Reprogramming.

Hoang T, Lambert JA, Martin R.

Curr Top Dev Biol. 2016;118:163-204. doi: 10.1016/bs.ctdb.2016.01.004. Epub 2016 Feb 18. Review.

PMID:
27137657
4.

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.

Leukemia. 2012 Aug;26(8):1829-41. doi: 10.1038/leu.2012.49. Epub 2012 Feb 20.

5.

HoxA3 is an apical regulator of haemogenic endothelium.

Iacovino M, Chong D, Szatmari I, Hartweck L, Rux D, Caprioli A, Cleaver O, Kyba M.

Nat Cell Biol. 2011 Jan;13(1):72-8. doi: 10.1038/ncb2137. Epub 2010 Dec 19.

6.

Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.

Tornack J, Seiler K, Grützkau A, Grün JR, Onodera M, Melchers F, Tsuneto M.

PLoS One. 2013 Jul 29;8(7):e70116. doi: 10.1371/journal.pone.0070116. Print 2013.

7.

Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells.

Ross K, Sedello AK, Todd GP, Paszkowski-Rogacz M, Bird AW, Ding L, Grinenko T, Behrens K, Hubner N, Mann M, Waskow C, Stocking C, Buchholz F.

Blood. 2012 May 3;119(18):4152-61. doi: 10.1182/blood-2011-09-382390. Epub 2012 Mar 12.

8.

Chromatin regulation by RUNX1.

Lichtinger M, Hoogenkamp M, Krysinska H, Ingram R, Bonifer C.

Blood Cells Mol Dis. 2010 Apr 15;44(4):287-90. doi: 10.1016/j.bcmd.2010.02.009. Epub 2010 Mar 2.

PMID:
20194037
9.

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.

Landry JR, Kinston S, Knezevic K, de Bruijn MF, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K, Göttgens B.

Blood. 2008 Mar 15;111(6):3005-14. doi: 10.1182/blood-2007-07-098830. Epub 2008 Jan 9.

10.

A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis.

Knezevic K, Bee T, Wilson NK, Janes ME, Kinston S, Polderdijk S, Kolb-Kokocinski A, Ottersbach K, Pencovich N, Groner Y, de Bruijn M, Göttgens B, Pimanda JE.

Mol Cell Biol. 2011 Jul;31(14):2817-26. doi: 10.1128/MCB.01305-10. Epub 2011 May 16.

11.

DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo.

Webber BR, Iacovino M, Choi SH, Tolar J, Kyba M, Blazar BR.

Blood. 2013 Oct 24;122(17):2978-86. doi: 10.1182/blood-2013-03-489369. Epub 2013 Sep 12.

12.

Taking the Leap: Runx1 in the Formation of Blood from Endothelium.

Tober J, Maijenburg MW, Speck NA.

Curr Top Dev Biol. 2016;118:113-62. doi: 10.1016/bs.ctdb.2016.01.008. Epub 2016 Feb 18. Review.

PMID:
27137656
13.

Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.

Majumder A, Syed KM, Joseph S, Scambler PJ, Dutta D.

J Biol Chem. 2015 May 22;290(21):13053-63. doi: 10.1074/jbc.M114.615492. Epub 2015 Apr 6.

14.

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia.

Martens JH, Mandoli A, Simmer F, Wierenga BJ, Saeed S, Singh AA, Altucci L, Vellenga E, Stunnenberg HG.

Blood. 2012 Nov 8;120(19):4038-48. doi: 10.1182/blood-2012-05-429050. Epub 2012 Sep 14.

15.

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.

Maicas M, Vázquez I, Vicente C, García-Sánchez MA, Marcotegui N, Urquiza L, Calasanz MJ, Odero MD.

Oncogene. 2013 Apr 18;32(16):2069-78. doi: 10.1038/onc.2012.222. Epub 2012 Jun 11.

PMID:
22689058
16.

Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome.

De Vita S, Canzonetta C, Mulligan C, Delom F, Groet J, Baldo C, Vanes L, Dagna-Bricarelli F, Hoischen A, Veltman J, Fisher EM, Tybulewicz VL, Nizetic D.

Oncogene. 2010 Nov 18;29(46):6102-14. doi: 10.1038/onc.2010.351. Epub 2010 Aug 9.

17.

The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors.

Cooper S, Guo H, Friedman AD.

PLoS One. 2015 May 4;10(5):e0126385. doi: 10.1371/journal.pone.0126385. eCollection 2015.

18.

Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.

Guo H, Ma O, Speck NA, Friedman AD.

Blood. 2012 May 10;119(19):4408-18. doi: 10.1182/blood-2011-12-397091. Epub 2012 Mar 26.

19.

Cell cycle and developmental control of hematopoiesis by Runx1.

Friedman AD.

J Cell Physiol. 2009 Jun;219(3):520-4. doi: 10.1002/jcp.21738. Review.

20.

Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.

Li X, Vradii D, Gutierrez S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Javed A.

J Cell Biochem. 2005 Nov 1;96(4):795-809.

PMID:
16149049

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