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Items: 1 to 20 of 117

1.

In vitro inhibition of SKOV-3 cell migration as a distinctive feature of progesterone receptor membrane component type 2 versus type 1.

Albrecht C, Huck V, Wehling M, Wendler A.

Steroids. 2012 Dec;77(14):1543-50. doi: 10.1016/j.steroids.2012.09.006. Epub 2012 Oct 12.

PMID:
23064006
2.

PGRMC2, a yet uncharacterized protein with potential as tumor suppressor, migration inhibitor, and regulator of cytochrome P450 enzyme activity.

Wendler A, Wehling M.

Steroids. 2013 Jun;78(6):555-8. doi: 10.1016/j.steroids.2012.12.002. Epub 2012 Dec 28.

PMID:
23276631
3.

Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice.

Peluso JJ, Gawkowska A, Liu X, Shioda T, Pru JK.

Endocrinology. 2009 Nov;150(11):4846-54. doi: 10.1210/en.2009-0730. Epub 2009 Oct 1.

PMID:
19797399
4.

Progesterone receptor membrane component-1 (PGRMC1) and PGRMC-2 interact to suppress entry into the cell cycle in spontaneously immortalized rat granulosa cells.

Peluso JJ, Griffin D, Liu X, Horne M.

Biol Reprod. 2014 Nov;91(5):104. doi: 10.1095/biolreprod.114.122986. Epub 2014 Sep 24.

5.

Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1.

Peluso JJ, Liu X, Saunders MM, Claffey KP, Phoenix K.

J Clin Endocrinol Metab. 2008 May;93(5):1592-9. doi: 10.1210/jc.2007-2771. Epub 2008 Mar 4.

PMID:
18319313
7.

Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells.

Wendler A, Keller D, Albrecht C, Peluso JJ, Wehling M.

Oncol Rep. 2011 Jan;25(1):273-9.

PMID:
21109987
8.
9.

Transcriptional analysis of novel hormone receptors PGRMC1 and PGRMC2 as potential biomarkers of breast adenocarcinoma staging.

Causey MW, Huston LJ, Harold DM, Charaba CJ, Ippolito DL, Hoffer ZS, Brown TA, Stallings JD.

J Surg Res. 2011 Dec;171(2):615-22. doi: 10.1016/j.jss.2010.04.034. Epub 2010 May 20.

PMID:
20655063
10.

Progesterone receptor membrane component 1 modulates human cytochrome p450 activities in an isoform-dependent manner.

Oda S, Nakajima M, Toyoda Y, Fukami T, Yokoi T.

Drug Metab Dispos. 2011 Nov;39(11):2057-65. doi: 10.1124/dmd.111.040907. Epub 2011 Aug 8.

11.

Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase.

Szczesna-Skorupa E, Kemper B.

Mol Pharmacol. 2011 Mar;79(3):340-50. doi: 10.1124/mol.110.068478. Epub 2010 Nov 16.

12.

PGRMC1-dependent autophagy by hyperoside induces apoptosis and sensitizes ovarian cancer cells to cisplatin treatment.

Zhu X, Ji M, Han Y, Guo Y, Zhu W, Gao F, Yang X, Zhang C.

Int J Oncol. 2017 Mar;50(3):835-846. doi: 10.3892/ijo.2017.3873. Epub 2017 Feb 10.

PMID:
28197632
13.

Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule.

Ahmed IS, Rohe HJ, Twist KE, Mattingly MN, Craven RJ.

J Pharmacol Exp Ther. 2010 May;333(2):564-73. doi: 10.1124/jpet.109.164210. Epub 2010 Feb 17.

14.

Progesterone protects ovarian cancer cells from cisplatin-induced inhibitory effects through progesterone receptor membrane component 1/2 as well as AKT signaling.

Zhu X, Han Y, Fang Z, Wu W, Ji M, Teng F, Zhu W, Yang X, Jia X, Zhang C.

Oncol Rep. 2013 Nov;30(5):2488-94. doi: 10.3892/or.2013.2680. Epub 2013 Aug 21.

PMID:
23970345
15.

S2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling.

Ahmed IS, Chamberlain C, Craven RJ.

Expert Opin Drug Metab Toxicol. 2012 Mar;8(3):361-70. doi: 10.1517/17425255.2012.658367. Epub 2012 Feb 1. Review.

PMID:
22292588
16.

Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence.

Clark NC, Pru CA, Yee SP, Lydon JP, Peluso JJ, Pru JK.

Endocrinology. 2017 Mar 1;158(3):640-651. doi: 10.1210/en.2016-1701.

17.

Alterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosis.

Keator CS, Mah K, Slayden OD.

Mol Hum Reprod. 2012 Jun;18(6):308-19. doi: 10.1093/molehr/gas006. Epub 2012 Feb 3.

18.

PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.

Lin ST, May EW, Chang JF, Hu RY, Wang LH, Chan HL.

Cell Mol Life Sci. 2015 Jun;72(12):2395-409. doi: 10.1007/s00018-014-1831-9. Epub 2015 Jan 18. Erratum in: Cell Mol Life Sci. 2015 Jun;72(12):2411-3.

PMID:
25596698
19.
20.

Membrane-initiated effects of progesterone on proliferation and activation of VEGF in breast cancer cells.

Neubauer H, Adam G, Seeger H, Mueck AO, Solomayer E, Wallwiener D, Cahill MA, Fehm T.

Climacteric. 2009 Jun;12(3):230-9. doi: 10.1080/13697130802635637.

PMID:
19340614

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