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Items: 1 to 20 of 71


Turning on brown fat and muscle metabolism: hedging your bets.

Lee KY, Kahn CR.

Cell. 2012 Oct 12;151(2):248-50. doi: 10.1016/j.cell.2012.09.025.


Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.

Teperino R, Amann S, Bayer M, McGee SL, Loipetzberger A, Connor T, Jaeger C, Kammerer B, Winter L, Wiche G, Dalgaard K, Selvaraj M, Gaster M, Lee-Young RS, Febbraio MA, Knauf C, Cani PD, Aberger F, Penninger JM, Pospisilik JA, Esterbauer H.

Cell. 2012 Oct 12;151(2):414-26. doi: 10.1016/j.cell.2012.09.021.


Brown adipose tissue: development, metabolism and beyond.

Schulz TJ, Tseng YH.

Biochem J. 2013 Jul 15;453(2):167-78. doi: 10.1042/BJ20130457. Review.


Adipocyte lineages: tracing back the origins of fat.

Sanchez-Gurmaches J, Guertin DA.

Biochim Biophys Acta. 2014 Mar;1842(3):340-51. doi: 10.1016/j.bbadis.2013.05.027. Epub 2013 Jun 4. Review.


Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development.

Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5069-74. doi: 10.1073/pnas.1420978112. Epub 2015 Apr 6.


Brown adipose tissue: a potential target in the fight against obesity and the metabolic syndrome.

Poekes L, Lanthier N, Leclercq IA.

Clin Sci (Lond). 2015 Dec;129(11):933-49. doi: 10.1042/CS20150339. Review.


Developmental regulation of GLUT-1 (erythroid/Hep G2) and GLUT-4 (muscle/fat) glucose transporter expression in rat heart, skeletal muscle, and brown adipose tissue.

Santalucía T, Camps M, Castelló A, Muñoz P, Nuel A, Testar X, Palacin M, Zorzano A.

Endocrinology. 1992 Feb;130(2):837-46.


Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.

Guo T, Jou W, Chanturiya T, Portas J, Gavrilova O, McPherron AC.

PLoS One. 2009;4(3):e4937. doi: 10.1371/journal.pone.0004937. Epub 2009 Mar 19.


In vivo multi-tissue efficacy of peroxisome proliferator-activated receptor-γ therapy on glucose and fatty acid metabolism in obese type 2 diabetic rats.

Nemanich S, Rani S, Shoghi K.

Obesity (Silver Spring). 2013 Dec;21(12):2522-9. doi: 10.1002/oby.20378. Epub 2013 May 31.


Yes, even human brown fat is on fire!

Cannon B, Nedergaard J.

J Clin Invest. 2012 Feb;122(2):486-9. doi: 10.1172/JCI60941. Epub 2012 Jan 24.


Preparation methods prior to PET/CT scanning that decrease uptake of 18F-FDG by myocardium, brown adipose tissue, and skeletal muscle.

Shao D, Tian XW, Gao Q, Liang CH, Wang SX.

Acta Radiol. 2017 Jan;58(1):10-18. Epub 2016 Mar 2.


Ablation of the ID2 gene results in altered circadian feeding behavior, and sex-specific enhancement of insulin sensitivity and elevated glucose uptake in skeletal muscle and brown adipose tissue.

Mathew D, Zhou P, Pywell CM, van der Veen DR, Shao J, Xi Y, Bonar NA, Hummel AD, Chapman S, Leevy WM, Duffield GE.

PLoS One. 2013 Sep 2;8(9):e73064. doi: 10.1371/journal.pone.0073064. eCollection 2013.


Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism.

Rodríguez A, Ezquerro S, Méndez-Giménez L, Becerril S, Frühbeck G.

Am J Physiol Endocrinol Metab. 2015 Oct 15;309(8):E691-714. doi: 10.1152/ajpendo.00297.2015. Epub 2015 Sep 1. Review.


Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.

Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall LE, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, Tseng YH.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):143-8. doi: 10.1073/pnas.1010929108. Epub 2010 Dec 20.


BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis.

Qian SW, Tang Y, Li X, Liu Y, Zhang YY, Huang HY, Xue RD, Yu HY, Guo L, Gao HD, Liu Y, Sun X, Li YM, Jia WP, Tang QQ.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):E798-807. doi: 10.1073/pnas.1215236110. Epub 2013 Feb 6.


Adipose tissue plasticity during catch-up fat driven by thrifty metabolism: relevance for muscle-adipose glucose redistribution during catch-up growth.

Summermatter S, Marcelino H, Arsenijevic D, Buchala A, Aprikian O, Assimacopoulos-Jeannet F, Seydoux J, Montani JP, Solinas G, Dulloo AG.

Diabetes. 2009 Oct;58(10):2228-37. doi: 10.2337/db08-1793. Epub 2009 Jul 14.


Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat.

Schulz TJ, Huang P, Huang TL, Xue R, McDougall LE, Townsend KL, Cypess AM, Mishina Y, Gussoni E, Tseng YH.

Nature. 2013 Mar 21;495(7441):379-83. doi: 10.1038/nature11943. Epub 2013 Mar 13.


Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.

Pospisilik JA, Schramek D, Schnidar H, Cronin SJ, Nehme NT, Zhang X, Knauf C, Cani PD, Aumayr K, Todoric J, Bayer M, Haschemi A, Puviindran V, Tar K, Orthofer M, Neely GG, Dietzl G, Manoukian A, Funovics M, Prager G, Wagner O, Ferrandon D, Aberger F, Hui CC, Esterbauer H, Penninger JM.

Cell. 2010 Jan 8;140(1):148-60. doi: 10.1016/j.cell.2009.12.027.


Ontogenesis of muscle and adipose tissues and their interactions in ruminants and other species.

Bonnet M, Cassar-Malek I, Chilliard Y, Picard B.

Animal. 2010 Jul;4(7):1093-109. doi: 10.1017/S1751731110000601.


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