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Items: 1 to 20 of 193

2.
3.

Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.

Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV.

J Biol Chem. 2011 Jul 22;286(29):25947-62. doi: 10.1074/jbc.M111.243626. Epub 2011 May 19.

4.

Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.

Chen MC, Lee CF, Huang WH, Chou TC.

Biochem Pharmacol. 2013 May 1;85(9):1278-87. doi: 10.1016/j.bcp.2013.02.009. Epub 2013 Feb 14.

PMID:
23416116
5.

Endorepellin evokes autophagy in endothelial cells.

Poluzzi C, Casulli J, Goyal A, Mercer TJ, Neill T, Iozzo RV.

J Biol Chem. 2014 Jun 6;289(23):16114-28. doi: 10.1074/jbc.M114.556530. Epub 2014 Apr 15.

6.

Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathways.

Shen K, Ji L, Gong C, Ma Y, Yang L, Fan Y, Hou M, Wang Z.

Biochem Pharmacol. 2012 Sep 15;84(6):784-92. doi: 10.1016/j.bcp.2012.05.024. Epub 2012 Jul 4.

PMID:
22771629
7.

Endorepellin-evoked Autophagy Contributes to Angiostasis.

Goyal A, Gubbiotti MA, Chery DR, Han L, Iozzo RV.

J Biol Chem. 2016 Sep 9;291(37):19245-56. doi: 10.1074/jbc.M116.740266. Epub 2016 Jul 19.

8.

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV.

J Cell Biol. 2004 Jul 5;166(1):97-109. Erratum in: J Cell Biol. 2013 May 13;201(4):641.

9.

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.

Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV.

Blood. 2009 Nov 26;114(23):4897-906. doi: 10.1182/blood-2009-02-207134. Epub 2009 Sep 29.

10.
11.

GABARBP down-regulates HIF-1α expression through the VEGFR-2 and PI3K/mTOR/4E-BP1 pathways.

Park SH, Kim BR, Lee JH, Park ST, Lee SH, Dong SM, Rho SB.

Cell Signal. 2014 Jul;26(7):1506-13. doi: 10.1016/j.cellsig.2014.03.017. Epub 2014 Mar 29.

PMID:
24686084
12.

The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy.

Douglass S, Goyal A, Iozzo RV.

Connect Tissue Res. 2015;56(5):381-91. doi: 10.3109/03008207.2015.1045297. Epub 2015 Jul 16. Review.

13.

A current view of perlecan in physiology and pathology: A mosaic of functions.

Gubbiotti MA, Neill T, Iozzo RV.

Matrix Biol. 2017 Jan;57-58:285-298. doi: 10.1016/j.matbio.2016.09.003. Epub 2016 Sep 6. Review.

15.

Vascular endothelial growth factor regulates primate choroid-retinal endothelial cell proliferation and tube formation through PI3K/Akt and MEK/ERK dependent signaling.

Jin J, Yuan F, Shen MQ, Feng YF, He QL.

Mol Cell Biochem. 2013 Sep;381(1-2):267-72. doi: 10.1007/s11010-013-1710-y. Epub 2013 Jun 8.

PMID:
23749166
17.

Liquiritigenin inhibits serum-induced HIF-1α and VEGF expression via the AKT/mTOR-p70S6K signalling pathway in HeLa cells.

Xie SR, Wang Y, Liu CW, Luo K, Cai YQ.

Phytother Res. 2012 Aug;26(8):1133-41. doi: 10.1002/ptr.3696. Epub 2011 Dec 14.

PMID:
22170854
18.

Distinct roles of HIF1A in endothelial adaptations to physiological and ambient oxygen.

Jiang YZ, Li Y, Wang K, Dai CF, Huang SA, Chen DB, Zheng J.

Mol Cell Endocrinol. 2014 Jun 25;391(1-2):60-7. doi: 10.1016/j.mce.2014.04.008. Epub 2014 May 2.

19.

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.

Nieminen T, Toivanen PI, Rintanen N, Heikura T, Jauhiainen S, Airenne KJ, Alitalo K, Marjomäki V, Ylä-Herttuala S.

Biochim Biophys Acta. 2014 Jan;1840(1):454-63. doi: 10.1016/j.bbagen.2013.10.005. Epub 2013 Oct 8.

PMID:
24112971
20.

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