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DAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: an integrated proteomics and transcriptomics approach.

Goel A, Chhabra R, Ahmad S, Prasad AK, Parmar VS, Ghosh B, Saini N.

Cell Death Dis. 2012 Oct 11;3:e402. doi: 10.1038/cddis.2012.141.


Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: role of NF-kappaB, Akt, ROS and MAP kinase pathway.

Goel A, Prasad AK, Parmar VS, Ghosh B, Saini N.

Chem Biol Interact. 2009 May 15;179(2-3):363-74. doi: 10.1016/j.cbi.2008.10.060. Epub 2008 Nov 18.


Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.

MacKeigan JP, Clements CM, Lich JD, Pope RM, Hod Y, Ting JP.

Cancer Res. 2003 Oct 15;63(20):6928-34.


Increase in cell motility by carbon ion irradiation via the Rho signaling pathway and its inhibition by the ROCK inhibitor Y-27632 in lung adenocarcinoma A549 cells.

Murata K, Noda SE, Oike T, Takahashi A, Yoshida Y, Suzuki Y, Ohno T, Funayama T, Kobayashi Y, Takahashi T, Nakano T.

J Radiat Res. 2014 Jul;55(4):658-64. doi: 10.1093/jrr/rru002. Epub 2014 Mar 21.


FERM domain containing protein 7 interacts with the Rho GDP dissociation inhibitor and specifically activates Rac1 signaling.

Pu J, Mao Y, Lei X, Yan Y, Lu X, Tian J, Yin X, Zhao G, Zhang B.

PLoS One. 2013 Aug 13;8(8):e73108. doi: 10.1371/journal.pone.0073108. eCollection 2013.


BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.

Makrodouli E, Oikonomou E, Koc M, Andera L, Sasazuki T, Shirasawa S, Pintzas A.

Mol Cancer. 2011 Sep 23;10:118. doi: 10.1186/1476-4598-10-118.


A cross-link between protein kinase A and Rho-family GTPases signaling mediates cell-cell adhesion and actin cytoskeleton organization in epithelial cancer cells.

Leve F, de Souza W, Morgado-Díaz JA.

J Pharmacol Exp Ther. 2008 Dec;327(3):777-88. doi: 10.1124/jpet.108.140798. Epub 2008 Sep 12.


eIF5A1/RhoGDIα pathway: a novel therapeutic target for treatment of spinal cord injury identified by a proteomics approach.

Liu W, Shang FF, Xu Y, Belegu V, Xia L, Zhao W, Liu R, Wang W, Liu J, Li CY, Wang TH.

Sci Rep. 2015 Nov 23;5:16911. doi: 10.1038/srep16911.


The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.

Lim GE, Xu M, Sun J, Jin T, Brubaker PL.

Endocrinology. 2009 Dec;150(12):5249-61. doi: 10.1210/en.2009-0508. Epub 2009 Oct 9.


Role of Rho-specific guanine nucleotide dissociation inhibitor α regulation in cell migration.

Xie F, Shao S, Aziz AUR, Zhang B, Wang H, Liu B.

Acta Histochem. 2017 Apr;119(3):183-189. doi: 10.1016/j.acthis.2017.01.008. Epub 2017 Feb 8. Review.


Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells.

Eitaki M, Yamamori T, Meike S, Yasui H, Inanami O.

BMC Cancer. 2012 Oct 12;12:469. doi: 10.1186/1471-2407-12-469.


Knockdown of RhoGDIα induces apoptosis and increases lung cancer cell chemosensitivity to paclitaxel.

Rong F, Li W, Chen K, Li DM, Duan WM, Feng YZ, Li F, Zhou XW, Fan SJ, Liu Y, Tao M.

Neoplasma. 2012;59(5):541-50. doi: 10.4149/neo_2012_070.


Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration.

Schram K, Ganguly R, No EK, Fang X, Thong FS, Sweeney G.

Endocrinology. 2011 May;152(5):2037-47. doi: 10.1210/en.2010-1166. Epub 2011 Mar 8.


Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth.

Murphy GA, Solski PA, Jillian SA, Pérez de la Ossa P, D'Eustachio P, Der CJ, Rush MG.

Oncogene. 1999 Jul 1;18(26):3831-45.

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