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The Wnt/β-catenin pathway cross-talks with STAT3 signaling to regulate survival of retinal pigment epithelium cells.

Fragoso MA, Patel AK, Nakamura RE, Yi H, Surapaneni K, Hackam AS.

PLoS One. 2012;7(10):e46892. doi: 10.1371/journal.pone.0046892. Epub 2012 Oct 4.


Activation of Wnt/β-catenin signaling in Muller glia protects photoreceptors in a mouse model of inherited retinal degeneration.

Patel AK, Surapaneni K, Yi H, Nakamura RE, Karli SZ, Syeda S, Lee T, Hackam AS.

Neuropharmacology. 2015 Apr;91:1-12. doi: 10.1016/j.neuropharm.2014.11.015. Epub 2014 Dec 6.


The pathogenic role of the canonical Wnt pathway in age-related macular degeneration.

Zhou T, Hu Y, Chen Y, Zhou KK, Zhang B, Gao G, Ma JX.

Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4371-9. doi: 10.1167/iovs.09-4278. Epub 2009 Oct 29.


Modulation of Wnt3a-mediated nuclear beta-catenin accumulation and activation by integrin-linked kinase in mammalian cells.

Oloumi A, Syam S, Dedhar S.

Oncogene. 2006 Dec 14;25(59):7747-57. Epub 2006 Jun 26.


Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism.

Patel AK, Hackam AS.

Mol Immunol. 2013 Jun;54(2):122-31. doi: 10.1016/j.molimm.2012.11.005. Epub 2012 Dec 23.


Enhancement of canonical Wnt/β-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells.

Liu J, Ding X, Tang J, Cao Y, Hu P, Zhou F, Shan X, Cai X, Chen Q, Ling N, Zhang B, Bi Y, Chen K, Ren H, Huang A, He TC, Tang N.

PLoS One. 2011;6(11):e27496. doi: 10.1371/journal.pone.0027496. Epub 2011 Nov 15.


Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis.

Thomas RS, Clarke AR, Duance VC, Blain EJ.

Arthritis Res Ther. 2011;13(6):R203. doi: 10.1186/ar3536. Epub 2011 Dec 9.


Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.

Vikram A, Kim YR, Kumar S, Naqvi A, Hoffman TA, Kumar A, Miller FJ Jr, Kim CS, Irani K.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2301-9. doi: 10.1161/ATVBAHA.114.304338. Epub 2014 Aug 21.


SirT1 and STAT3 protect retinal pigmented epithelium cells against oxidative stress.

Li L, Wei W, Zhang Y, Tu G, Zhang Y, Yang J, Xing Y.

Mol Med Rep. 2015 Aug;12(2):2231-8. doi: 10.3892/mmr.2015.3570. Epub 2015 Mar 31.


Interaction of Wnt/β-catenin and notch signaling in the early stage of cardiac differentiation of P19CL6 cells.

Li B, Jia Z, Wang T, Wang W, Zhang C, Chen P, Ma K, Zhou C.

J Cell Biochem. 2012 Feb;113(2):629-39. doi: 10.1002/jcb.23390.


The Wnt signaling pathway protects retinal ganglion cell 5 (RGC-5) cells from elevated pressure.

Fragoso MA, Yi H, Nakamura RE, Hackam AS.

Cell Mol Neurobiol. 2011 Jan;31(1):163-73. doi: 10.1007/s10571-010-9603-z.


Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress.

Wang K, Jiang Y, Wang W, Ma J, Chen M.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):541-7. doi: 10.1016/j.bbrc.2015.10.117. Epub 2015 Oct 24.


Glucosamine inhibits epidermal growth factor-induced proliferation and cell-cycle progression in retinal pigment epithelial cells.

Liang CM, Tai MC, Chang YH, Chen YH, Chen CL, Chien MW, Chen JT.

Mol Vis. 2010 Dec 3;16:2559-71.


Wnt/beta-catenin signaling down-regulates N-acetylglucosaminyltransferase III expression: the implications of two mutually exclusive pathways for regulation.

Xu Q, Akama R, Isaji T, Lu Y, Hashimoto H, Kariya Y, Fukuda T, Du Y, Gu J.

J Biol Chem. 2011 Feb 11;286(6):4310-8. doi: 10.1074/jbc.M110.182576. Epub 2010 Nov 29.


Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cells.

Silvério KG, Davidson KC, James RG, Adams AM, Foster BL, Nociti FH Jr, Somerman MJ, Moon RT.

J Periodontal Res. 2012 Jun;47(3):309-19. doi: 10.1111/j.1600-0765.2011.01433.x. Epub 2011 Dec 11.


Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts.

Nakashima A, Katagiri T, Tamura M.

J Biol Chem. 2005 Nov 11;280(45):37660-8. Epub 2005 Sep 2.


Astaxanthin protects ARPE-19 cells from oxidative stress via upregulation of Nrf2-regulated phase II enzymes through activation of PI3K/Akt.

Li Z, Dong X, Liu H, Chen X, Shi H, Fan Y, Hou D, Zhang X.

Mol Vis. 2013 Jul 25;19:1656-66. Print 2013.


Rho GTPase activity modulates Wnt3a/beta-catenin signaling.

Rossol-Allison J, Stemmle LN, Swenson-Fields KI, Kelly P, Fields PE, McCall SJ, Casey PJ, Fields TA.

Cell Signal. 2009 Nov;21(11):1559-68. doi: 10.1016/j.cellsig.2009.05.010. Epub 2009 May 29.


Hyperglycaemia exacerbates choroidal neovascularisation in mice via the oxidative stress-induced activation of STAT3 signalling in RPE cells.

Li X, Cai Y, Wang YS, Shi YY, Hou W, Xu CS, Wang HY, Ye Z, Yao LB, Zhang J.

PLoS One. 2012;7(10):e47600. doi: 10.1371/journal.pone.0047600. Epub 2012 Oct 19.

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