Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 106


Heteromeric p97/p97R155C complexes induce dominant negative changes in wild-type and autophagy 9-deficient Dictyostelium strains.

Arhzaouy K, Strucksberg KH, Tung SM, Tangavelou K, Stumpf M, Faix J, Schröder R, Clemen CS, Eichinger L.

PLoS One. 2012;7(10):e46879. doi: 10.1371/journal.pone.0046879. Epub 2012 Oct 3.


Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers.

Rijal R, Arhzaouy K, Strucksberg KH, Cross M, Hofmann A, Schröder R, Clemen CS, Eichinger L.

Eur J Cell Biol. 2016 Jun-Jul;95(6-7):195-207. doi: 10.1016/j.ejcb.2016.03.004. Epub 2016 Apr 7.


The two Dictyostelium discoideum autophagy 8 proteins have distinct autophagic functions.

Meßling S, Matthias J, Xiong Q, Fischer S, Eichinger L.

Eur J Cell Biol. 2017 Jun;96(4):312-324. doi: 10.1016/j.ejcb.2017.03.014. Epub 2017 Apr 4.


IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation.

Bayraktar O, Oral O, Kocaturk NM, Akkoc Y, Eberhart K, Kosar A, Gozuacik D.

PLoS One. 2016 Oct 21;11(10):e0164864. doi: 10.1371/journal.pone.0164864. eCollection 2016. Erratum in: PLoS One. 2016 Nov 18;11(11):e0167192.


The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions.

Xiong Q, Ünal C, Matthias J, Steinert M, Eichinger L.

Open Biol. 2015 Apr;5(4):150008. doi: 10.1098/rsob.150008.


A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.

Erzurumlu Y, Kose FA, Gozen O, Gozuacik D, Toth EA, Ballar P.

Int J Biochem Cell Biol. 2013 Apr;45(4):773-82. doi: 10.1016/j.biocel.2013.01.006. Epub 2013 Jan 16.


Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation.

Halawani D, LeBlanc AC, Rouiller I, Michnick SW, Servant MJ, Latterich M.

Mol Cell Biol. 2009 Aug;29(16):4484-94. doi: 10.1128/MCB.00252-09. Epub 2009 Jun 8.


Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.

Weihl CC, Dalal S, Pestronk A, Hanson PI.

Hum Mol Genet. 2006 Jan 15;15(2):189-99. Epub 2005 Dec 1.


Pathological consequences of VCP mutations on human striated muscle.

Hübbers CU, Clemen CS, Kesper K, Böddrich A, Hofmann A, Kämäräinen O, Tolksdorf K, Stumpf M, Reichelt J, Roth U, Krause S, Watts G, Kimonis V, Wattjes MP, Reimann J, Thal DR, Biermann K, Evert BO, Lochmüller H, Wanker EE, Schoser BG, Noegel AA, Schröder R.

Brain. 2007 Feb;130(Pt 2):381-93. Epub 2006 Sep 19.


Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.

Weihl CC, Miller SE, Hanson PI, Pestronk A.

Hum Mol Genet. 2007 Apr 15;16(8):919-28. Epub 2007 Feb 28.


VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.

Tresse E, Salomons FA, Vesa J, Bott LC, Kimonis V, Yao TP, Dantuma NP, Taylor JP.

Autophagy. 2010 Feb;6(2):217-27. Epub 2010 Feb 22.


Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy.

Ju JS, Weihl CC.

Hum Mol Genet. 2010 Apr 15;19(R1):R38-45. doi: 10.1093/hmg/ddq157. Epub 2010 Apr 21. Review.


The two Dictyostelium autophagy eight proteins, ATG8a and ATG8b, associate with the autophagosome in succession.

Matthias J, Meßling S, Eichinger L.

Eur J Cell Biol. 2016 Jan;95(1):15-25. doi: 10.1016/j.ejcb.2015.10.007. Epub 2015 Nov 22.


Valosin-containing protein gene mutations: clinical and neuropathologic features.

Guyant-Maréchal L, Laquerrière A, Duyckaerts C, Dumanchin C, Bou J, Dugny F, Le Ber I, Frébourg T, Hannequin D, Campion D.

Neurology. 2006 Aug 22;67(4):644-51. Epub 2006 Jun 21.


Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila.

Tung SM, Unal C, Ley A, Peña C, Tunggal B, Noegel AA, Krut O, Steinert M, Eichinger L.

Cell Microbiol. 2010 Jun;12(6):765-80. doi: 10.1111/j.1462-5822.2010.01432.x. Epub 2010 Jan 11.


ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

Esaki M, Ogura T.

Biochem Cell Biol. 2010 Feb;88(1):109-17. doi: 10.1139/o09-116. Review.


Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease.

Ju JS, Miller SE, Hanson PI, Weihl CC.

J Biol Chem. 2008 Oct 31;283(44):30289-99. doi: 10.1074/jbc.M805517200. Epub 2008 Aug 20.


Imbalances in p97 co-factor interactions in human proteinopathy.

Fernández-Sáiz V, Buchberger A.

EMBO Rep. 2010 Jun;11(6):479-85. doi: 10.1038/embor.2010.49. Epub 2010 Apr 23.


A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.

Tang WK, Li D, Li CC, Esser L, Dai R, Guo L, Xia D.

EMBO J. 2010 Jul 7;29(13):2217-29. doi: 10.1038/emboj.2010.104. Epub 2010 May 28.


Recent advances in p97/VCP/Cdc48 cellular functions.

Yamanaka K, Sasagawa Y, Ogura T.

Biochim Biophys Acta. 2012 Jan;1823(1):130-7. doi: 10.1016/j.bbamcr.2011.07.001. Epub 2011 Jul 12. Review.

Supplemental Content

Support Center