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Items: 1 to 20 of 121

1.

A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis.

Ruiz M, Courilleau D, Jullian JC, Fortin D, Ventura-Clapier R, Blondeau JP, Garnier A.

PLoS One. 2012;7(10):e46753. doi: 10.1371/journal.pone.0046753. Epub 2012 Oct 3.

2.

Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis.

Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F, Chang Y.

PLoS One. 2010 Jul 22;5(7):e11707. doi: 10.1371/journal.pone.0011707.

3.

Cilostazol promotes mitochondrial biogenesis in human umbilical vein endothelial cells through activating the expression of PGC-1α.

Zuo L, Li Q, Sun B, Xu Z, Ge Z.

Biochem Biophys Res Commun. 2013 Mar 29;433(1):52-7. doi: 10.1016/j.bbrc.2013.02.068. Epub 2013 Feb 26.

PMID:
23485471
4.

Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.

Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14379-84. Epub 2006 Sep 15.

5.

PGC-1α mediates differentiation of mesenchymal stem cells to brown adipose cells.

Huang PI, Chen YC, Chen LH, Juan CC, Ku HH, Wang ST, Chiou SH, Chiou GY, Chi CW, Hsu CC, Lee HC, Chen LK, Kao CL.

J Atheroscler Thromb. 2011;18(11):966-80. Epub 2011 Aug 5.

6.

Roles of transcriptional corepressor RIP140 and coactivator PGC-1α in energy state of chronically infarcted rat hearts and mitochondrial function of cardiomyocytes.

Chen Y, Wang Y, Chen J, Chen X, Cao W, Chen S, Xu S, Huang H, Liu P.

Mol Cell Endocrinol. 2012 Oct 15;362(1-2):11-8. doi: 10.1016/j.mce.2012.03.023. Epub 2012 Apr 5.

PMID:
22503866
7.

Cardioprotection by acetylcholine: a novel mechanism via mitochondrial biogenesis and function involving the PGC-1α pathway.

Sun L, Zhao M, Yu XJ, Wang H, He X, Liu JK, Zang WJ.

J Cell Physiol. 2013 Jun;228(6):1238-48. doi: 10.1002/jcp.24277.

PMID:
23139024
8.

PGC-1α induces mitochondrial and myokine transcriptional programs and lipid droplet and glycogen accumulation in cultured human skeletal muscle cells.

Mormeneo E, Jimenez-Mallebrera C, Palomer X, De Nigris V, Vázquez-Carrera M, Orozco A, Nascimento A, Colomer J, Lerín C, Gómez-Foix AM.

PLoS One. 2012;7(1):e29985. doi: 10.1371/journal.pone.0029985. Epub 2012 Jan 17.

9.
10.

Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis.

Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, Ciriolo MR.

J Biol Chem. 2010 Jul 9;285(28):21590-9. doi: 10.1074/jbc.M109.070169. Epub 2010 May 6.

11.

Aluminium induced oxidative stress results in decreased mitochondrial biogenesis via modulation of PGC-1α expression.

Sharma DR, Sunkaria A, Wani WY, Sharma RK, Kandimalla RJ, Bal A, Gill KD.

Toxicol Appl Pharmacol. 2013 Dec 1;273(2):365-80. doi: 10.1016/j.taap.2013.09.012. Epub 2013 Sep 29.

PMID:
24084166
12.

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP.

Circ Res. 2004 Mar 5;94(4):525-33. Epub 2004 Jan 15.

13.

Ligand-dependent coactivation of the human bile acid receptor FXR by the peroxisome proliferator-activated receptor gamma coactivator-1alpha.

Savkur RS, Thomas JS, Bramlett KS, Gao Y, Michael LF, Burris TP.

J Pharmacol Exp Ther. 2005 Jan;312(1):170-8. Epub 2004 Aug 25.

14.

Decreased mRNA expression of PGC-1α and PGC-1α-regulated factors in the SOD1G93A ALS mouse model and in human sporadic ALS.

Thau N, Knippenberg S, Körner S, Rath KJ, Dengler R, Petri S.

J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.

15.

Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity.

Won JC, Park JY, Kim YM, Koh EH, Seol S, Jeon BH, Han J, Kim JR, Park TS, Choi CS, Lee WJ, Kim MS, Lee IK, Youn JH, Lee KU.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):290-7. doi: 10.1161/ATVBAHA.109.198721. Epub 2009 Dec 3. Erratum in: Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):e175.

16.

Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand.

Willy PJ, Murray IR, Qian J, Busch BB, Stevens WC Jr, Martin R, Mohan R, Zhou S, Ordentlich P, Wei P, Sapp DW, Horlick RA, Heyman RA, Schulman IG.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8912-7. Epub 2004 Jun 7.

17.

The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents.

Morari J, Torsoni AS, Anhê GF, Roman EA, Cintra DE, Ward LS, Bordin S, Velloso LA.

Metabolism. 2010 Feb;59(2):215-23. doi: 10.1016/j.metabol.2009.07.020. Epub 2009 Sep 18.

PMID:
19766270
18.

AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells.

Irrcher I, Ljubicic V, Kirwan AF, Hood DA.

PLoS One. 2008;3(10):e3614. doi: 10.1371/journal.pone.0003614. Epub 2008 Oct 31.

19.

Identification and characterization of an alternative promoter of the human PGC-1alpha gene.

Yoshioka T, Inagaki K, Noguchi T, Sakai M, Ogawa W, Hosooka T, Iguchi H, Watanabe E, Matsuki Y, Hiramatsu R, Kasuga M.

Biochem Biophys Res Commun. 2009 Apr 17;381(4):537-43. doi: 10.1016/j.bbrc.2009.02.077. Epub 2009 Feb 20.

PMID:
19233136
20.

PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.

Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM, Hood DA.

Am J Physiol Cell Physiol. 2003 Jun;284(6):C1669-77.

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