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Items: 1 to 20 of 91

1.

Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice.

Wartman LD, Welch JS, Uy GL, Klco JM, Lamprecht T, Varghese N, Nagarajan R, Ley TJ.

PLoS One. 2012;7(10):e46529. doi: 10.1371/journal.pone.0046529. Epub 2012 Oct 8.

2.

Notch signaling in acute promyelocytic leukemia.

Grieselhuber NR, Klco JM, Verdoni AM, Lamprecht T, Sarkaria SM, Wartman LD, Ley TJ.

Leukemia. 2013 Jul;27(7):1548-1557. doi: 10.1038/leu.2013.68. Epub 2013 Mar 4.

3.

Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice.

Matsushita H, Yahata T, Sheng Y, Nakamura Y, Muguruma Y, Matsuzawa H, Tanaka M, Hayashi H, Sato T, Damdinsuren A, Onizuka M, Ito M, Miyachi H, Pandolfi PP, Ando K.

PLoS One. 2014 Nov 4;9(11):e111082. doi: 10.1371/journal.pone.0111082. eCollection 2014.

4.

PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.

Welch JS, Yuan W, Ley TJ.

J Clin Invest. 2011 Apr;121(4):1636-45. doi: 10.1172/JCI42953.

5.

PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.

Cole CB, Verdoni AM, Ketkar S, Leight ER, Russler-Germain DA, Lamprecht TL, Demeter RT, Magrini V, Ley TJ.

J Clin Invest. 2016 Jan;126(1):85-98. doi: 10.1172/JCI82897. Epub 2015 Nov 23.

6.

Highly purified primitive hematopoietic stem cells are PML-RARA negative and generate nonclonal progenitors in acute promyelocytic leukemia.

Turhan AG, Lemoine FM, Debert C, Bonnet ML, Baillou C, Picard F, Macintyre EA, Varet B.

Blood. 1995 Apr 15;85(8):2154-61.

7.

PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors.

Wojiski S, Guibal FC, Kindler T, Lee BH, Jesneck JL, Fabian A, Tenen DG, Gilliland DG.

Leukemia. 2009 Aug;23(8):1462-71. doi: 10.1038/leu.2009.63. Epub 2009 Mar 26.

8.

Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.

Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC.

Haematologica. 2015 Aug;100(8):1064-75. doi: 10.3324/haematol.2014.123018. Epub 2015 Jun 18.

9.

Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.

Welch JS, Klco JM, Varghese N, Nagarajan R, Ley TJ.

Blood. 2011 Feb 24;117(8):2460-8. doi: 10.1182/blood-2010-08-300087. Epub 2010 Dec 29.

10.
11.

Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation.

Vitaliano-Prunier A, Halftermeyer J, Ablain J, de Reynies A, Peres L, Le Bras M, Metzger D, de Thé H.

Blood. 2014 Dec 11;124(25):3772-80. doi: 10.1182/blood-2014-03-561852. Epub 2014 Sep 25.

12.

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.

Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Thomé C, Scheucher PS, Lange AP, Paiva HH, Hemmelgarn BT, Morais-Sobral MC, Azevedo EA, Franca-Neto PL, Franca RF, Silva CL, Krause A, Rego EM.

Oncotarget. 2017 Jan 31;8(5):8475-8483. doi: 10.18632/oncotarget.14295.

13.

Therapy-induced PML/RARA proteolysis and acute promyelocytic leukemia cure.

Nasr R, Lallemand-Breitenbach V, Zhu J, Guillemin MC, de Thé H.

Clin Cancer Res. 2009 Oct 15;15(20):6321-6. doi: 10.1158/1078-0432.CCR-09-0209. Epub 2009 Oct 6. Review.

14.

MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.

Zeng CW, Chen ZH, Zhang XJ, Han BW, Lin KY, Li XJ, Wei PP, Zhang H, Li Y, Chen YQ.

Autophagy. 2014 Oct 1;10(10):1726-37. doi: 10.4161/auto.29592. Epub 2014 Jul 18.

15.

Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Dekking EH, van der Velden VH, Varro R, Wai H, Böttcher S, Kneba M, Sonneveld E, Koning A, Boeckx N, Van Poecke N, Lucio P, Mendonça A, Sedek L, Szczepański T, Kalina T, Kanderová V, Hoogeveen P, Flores-Montero J, Chillón MC, Orfao A, Almeida J, Evans P, Cullen M, Noordijk AL, Vermeulen PM, de Man MT, Dixon EP, Comans-Bitter WM, van Dongen JJ; EuroFlow Consortium (EU-FP6, LSHB-CT-2006-018708).

Leukemia. 2012 Sep;26(9):1976-85. doi: 10.1038/leu.2012.125. Epub 2012 May 8.

16.

Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model.

Santana BA, Pintão MC, Abreu e Lima RS, Scheucher PS, Santos GA, Garcia AB, Falcão RP, Rego EM.

Braz J Med Biol Res. 2006 May;39(5):615-20. Epub 2006 Apr 20.

17.

Development and validation of a 3-Plex RT-qPCR assay for the simultaneous detection and quantitation of the three PML-RARa fusion transcripts in acute promyelocytic leukemia.

Chen Z, Tong Y, Li Y, Gao Q, Wang Q, Fu C, Xia Z.

PLoS One. 2015 Mar 27;10(3):e0122530. doi: 10.1371/journal.pone.0122530. eCollection 2015.

18.

[Detection of PML/RARa transcripts in acute promyelocytic leukemia by real-time quantitative reverse transcription polymerase chain reaction].

Lang L, Li HM, Liu H, Wang YM, Zhang XM.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Aug;15(4):714-9. Chinese.

PMID:
17708789
19.

Commonly dysregulated genes in murine APL cells.

Yuan W, Payton JE, Holt MS, Link DC, Watson MA, DiPersio JF, Ley TJ.

Blood. 2007 Feb 1;109(3):961-70. Epub 2006 Sep 28.

20.

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