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Items: 1 to 20 of 96

1.

Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier.

Ding M, Coward RJ, Jeansson M, Kim W, Quaggin SE.

Am J Physiol Renal Physiol. 2013 Jan 1;304(1):F120-6. doi: 10.1152/ajprenal.00416.2012. Epub 2012 Oct 10.

2.

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.

Ding M, Cui S, Li C, Jothy S, Haase V, Steer BM, Marsden PA, Pippin J, Shankland S, Rastaldi MP, Cohen CD, Kretzler M, Quaggin SE.

Nat Med. 2006 Sep;12(9):1081-7. Epub 2006 Aug 13.

PMID:
16906157
3.

Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease.

Brukamp K, Jim B, Moeller MJ, Haase VH.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1397-407. Epub 2007 Jul 3.

4.

Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein.

Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C.

Acta Physiol (Oxf). 2013 Mar;207(3):565-76. doi: 10.1111/apha.12058.

PMID:
23384425
5.
6.

Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.

Taylor M, Qu A, Anderson ER, Matsubara T, Martin A, Gonzalez FJ, Shah YM.

Gastroenterology. 2011 Jun;140(7):2044-55. doi: 10.1053/j.gastro.2011.03.007. Epub 2011 Mar 17.

7.

Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis.

Theilig F, Enke AK, Scolari B, Polzin D, Bachmann S, Koesters R.

Am J Pathol. 2011 Nov;179(5):2177-88. doi: 10.1016/j.ajpath.2011.07.012. Epub 2011 Sep 15.

8.

Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.

Shah YM, Ito S, Morimura K, Chen C, Yim SH, Haase VH, Gonzalez FJ.

Gastroenterology. 2008 Jun;134(7):2036-48, 2048.e1-3. doi: 10.1053/j.gastro.2008.03.009. Epub 2008 Mar 10.

9.

Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.

Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH.

Mol Cell Biol. 2005 Apr;25(8):3163-72.

10.

Modification in the von Hippel-Lindau protein is involved in the progression of experimentally induced rat glomerulonephritis.

Kudo Y, Kakinuma Y, Iguchi M, Sato T, Sugiura T, Furihata M, Shuin T.

Nephron Exp Nephrol. 2007;106(3):e97-106. Epub 2007 May 22.

PMID:
17519558
12.

Hypoxia-inducible factors in the kidney.

Haase VH.

Am J Physiol Renal Physiol. 2006 Aug;291(2):F271-81. Epub 2006 Mar 22. Review.

13.

Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria.

Steenhard BM, Isom K, Stroganova L, St John PL, Zelenchuk A, Freeburg PB, Holzman LB, Abrahamson DR.

Am J Pathol. 2010 Jul;177(1):84-96. doi: 10.2353/ajpath.2010.090767. Epub 2010 Jun 3.

14.

Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma.

Wright TM, Rathmell WK.

J Biol Chem. 2010 Apr 23;285(17):12916-24. doi: 10.1074/jbc.M109.073924. Epub 2010 Feb 25.

15.

Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer.

Schödel J, Grampp S, Maher ER, Moch H, Ratcliffe PJ, Russo P, Mole DR.

Eur Urol. 2016 Apr;69(4):646-57. doi: 10.1016/j.eururo.2015.08.007. Epub 2015 Aug 19. Review.

16.

HIFing the brakes: therapeutic opportunities for treatment of human malignancies.

Garcia JA.

Sci STKE. 2006 May 30;2006(337):pe25. Review.

PMID:
16738063
17.

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.

Hum Pathol. 2007 Sep;38(9):1310-20. Epub 2007 Jun 6. Erratum in: Hum Pathol. 2008 Jan;39(1):147. Mellilo, Giovanni [corrected to Melillo, Giovanni].

PMID:
17555795
18.

Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells.

Kurt B, Paliege A, Willam C, Schwarzensteiner I, Schucht K, Neymeyer H, Sequeira-Lopez ML, Bachmann S, Gomez RA, Eckardt KU, Kurtz A.

J Am Soc Nephrol. 2013 Feb;24(3):433-44. doi: 10.1681/ASN.2012080791. Epub 2013 Feb 7.

19.

Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.

Kai S, Tanaka T, Daijo H, Harada H, Kishimoto S, Suzuki K, Takabuchi S, Takenaga K, Fukuda K, Hirota K.

Antioxid Redox Signal. 2012 Feb 1;16(3):203-16. doi: 10.1089/ars.2011.3882. Epub 2011 Oct 17.

20.

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

Bollée G, Flamant M, Schordan S, Fligny C, Rumpel E, Milon M, Schordan E, Sabaa N, Vandermeersch S, Galaup A, Rodenas A, Casal I, Sunnarborg SW, Salant DJ, Kopp JB, Threadgill DW, Quaggin SE, Dussaule JC, Germain S, Mesnard L, Endlich K, Boucheix C, Belenfant X, Callard P, Endlich N, Tharaux PL.

Nat Med. 2011 Sep 25;17(10):1242-50. doi: 10.1038/nm.2491. Erratum in: Nat Med. 2011 Oct;17(10):2 p following 1250. Nat Med. 2011 Nov;17(11):1521.

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