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Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation.

He W, Wang Q, Xu J, Xu X, Padilla MT, Ren G, Gou X, Lin Y.

Autophagy. 2012 Dec;8(12):1811-21. doi: 10.4161/auto.22145. Epub 2012 Oct 10.


RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.

Luan Q, Jin L, Jiang CC, Tay KH, Lai F, Liu XY, Liu YL, Guo ST, Li CY, Yan XG, Tseng HY, Zhang XD.

Autophagy. 2015;11(7):975-94. doi: 10.1080/15548627.2015.1049800.


A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy.

He W, Wang Q, Srinivasan B, Xu J, Padilla MT, Li Z, Wang X, Liu Y, Gou X, Shen HM, Xing C, Lin Y.

Oncogene. 2014 Jun 5;33(23):3004-13. doi: 10.1038/onc.2013.256. Epub 2013 Jul 8.


A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells.

Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH, Kim YS.

Cancer Res. 2007 Aug 1;67(15):7327-34.


Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy.

Yang M, Liu L, Xie M, Sun X, Yu Y, Kang R, Yang L, Zhu S, Cao L, Tang D.

Autophagy. 2015;11(2):214-24. doi: 10.4161/15548627.2014.994400.


Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes.

García-Navas R, Munder M, Mollinedo F.

Autophagy. 2012 Nov;8(11):1557-76. doi: 10.4161/auto.21315. Epub 2012 Aug 9.


TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways.

Zhang L, Dittmer MR, Blackwell K, Workman LM, Hostager B, Habelhah H.

Cell Signal. 2015 Feb;27(2):306-14. doi: 10.1016/j.cellsig.2014.11.014. Epub 2014 Nov 18.


c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition.

Palumbo C, De Luca A, Rosato N, Forgione M, Rotili D, Caccuri AM.

J Transl Med. 2016 Feb 4;14:37. doi: 10.1186/s12967-016-0796-x.


RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation.

Zhang H, Zhang H, Lin Y, Li J, Pober JS, Min W.

J Biol Chem. 2007 May 18;282(20):14788-96. Epub 2007 Mar 27. Erratum in: J Biol Chem. 2007 Sep 14;282(37):27556. Zhang, Rong [corrected to Zhang, Haifeng].


The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells.

Li DD, Wang LL, Deng R, Tang J, Shen Y, Guo JF, Wang Y, Xia LP, Feng GK, Liu QQ, Huang WL, Zeng YX, Zhu XF.

Oncogene. 2009 Feb 12;28(6):886-98. doi: 10.1038/onc.2008.441. Epub 2008 Dec 8.


Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.

Kim SY, Lee DH, Song X, Bartlett DL, Kwon YT, Lee YJ.

Apoptosis. 2014 Nov;19(11):1603-15. doi: 10.1007/s10495-014-1028-6.


Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation.

Wong CH, Iskandar KB, Yadav SK, Hirpara JL, Loh T, Pervaiz S.

PLoS One. 2010 Apr 2;5(4):e9996. doi: 10.1371/journal.pone.0009996. Erratum in: PLoS One. 2016;11(7):e0159352.


TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation.

You M, Savaraj N, Kuo MT, Wangpaichitr M, Varona-Santos J, Wu C, Nguyen DM, Feun L.

Mol Cell Biochem. 2013 Feb;374(1-2):181-90. doi: 10.1007/s11010-012-1518-1. Epub 2012 Nov 20.


Autophagy-Mediated Degradation of IAPs and c-FLIP(L) Potentiates Apoptosis Induced by Combination of TRAIL and Chal-24.

Xu J, Xu X, Shi S, Wang Q, Saxton B, He W, Gou X, Jang JH, Nyunoya T, Wang X, Xing C, Zhang L, Lin Y.

J Cell Biochem. 2016 May;117(5):1136-44. doi: 10.1002/jcb.25397. Epub 2015 Nov 2.


In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8.

Gentle IE, Wong WW, Evans JM, Bankovacki A, Cook WD, Khan NR, Nachbur U, Rickard J, Anderton H, Moulin M, Lluis JM, Moujalled DM, Silke J, Vaux DL.

J Biol Chem. 2011 Apr 15;286(15):13282-91. doi: 10.1074/jbc.M110.216226. Epub 2011 Feb 21. Erratum in: J Biol Chem. 2016 Jan 29;291(5):2547.


TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis.

Karl I, Jossberger-Werner M, Schmidt N, Horn S, Goebeler M, Leverkus M, Wajant H, Giner T.

Cell Death Dis. 2014 Oct 9;5:e1444. doi: 10.1038/cddis.2014.404. Erratum in: Cell Death Dis. 2014;5:e1556.


Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M.

Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Review.


The activation of c-Jun NH₂-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells.

Jia G, Kong R, Ma ZB, Han B, Wang YW, Pan SH, Li YH, Sun B.

J Exp Clin Cancer Res. 2014 Jan 18;33:8. doi: 10.1186/1756-9966-33-8.


Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells.

Cheng X, Liu H, Jiang CC, Fang L, Chen C, Zhang XD, Jiang ZW.

Int J Mol Med. 2014 Sep;34(3):772-81. doi: 10.3892/ijmm.2014.1822. Epub 2014 Jun 25.


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