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Items: 1 to 20 of 105


Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model.

Li J, Wu RG, Meng FY, Wang Z, Wang CM, Wang YY, Zhang ZJ.

PLoS One. 2012;7(9):e45811. doi: 10.1371/journal.pone.0045811. Epub 2012 Sep 26.


Synergistic mechanism of gene expression and pathways between jasminoidin and ursodeoxycholic acid in treating focal cerebral ischemia-reperfusion injury.

Liu J, Zhou CX, Zhang ZJ, Wang LY, Jing ZW, Wang Z.

CNS Neurosci Ther. 2012 Aug;18(8):674-82. doi: 10.1111/j.1755-5949.2012.00348.x. Epub 2012 Jun 22.


A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury.

Zhang ZJ, Li P, Wang Z, Li PT, Zhang WS, Sun ZH, Zhang XJ, Wang YY.

Brain Res. 2006 Dec 6;1123(1):188-95. Epub 2006 Oct 27.


Comparison of the network structural characteristics of calcium signaling pathway in cerebral ischemia after intervention by different components of Chinese medicine.

Jing ZW, Yan ZL, Zhou CX, Wang LY, Liu J, Wu HL, Zhang ZJ, Li M, Li PT, Zhou J, Wang Z.

J Tradit Chin Med. 2011 Sep;31(3):251-5.


Entropy-based divergent and convergent modular pattern reveals additive and synergistic anticerebral ischemia mechanisms.

Yu Y, Zhang X, Li B, Zhang Y, Liu J, Li H, Chen Y, Wang P, Kang R, Wu H, Wang Z.

Exp Biol Med (Maywood). 2016 Dec;241(18):2063-2074. doi: 10.1177/1535370216662361. Epub 2016 Aug 10.


An effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulae.

Li S, Wu C, Chen J, Lu P, Chen C, Fu M, Fang J, Gao J, Zhu L, Liang R, Shen X, Yang H.

PLoS One. 2013 Nov 13;8(11):e78902. doi: 10.1371/journal.pone.0078902. eCollection 2013.


Ameliorative effects of a combination of baicalin, jasminoidin and cholic acid on ibotenic acid-induced dementia model in rats.

Zhang J, Li P, Wang Y, Liu J, Zhang Z, Cheng W, Wang Y.

PLoS One. 2013;8(2):e56658. doi: 10.1371/journal.pone.0056658. Epub 2013 Feb 20. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/4588b718-f48e-4bf4-a387-e56f0a1be19e.


Variation of pathways and network profiles reveals the differential pharmacological mechanisms of each effective component to treat middle cerebral artery ischemia-reperfusion mice.

Dang H, Li K, Yu Y, Zhang Y, Liu J, Wang P, Li B, Wang H, Li H, Wang Z, Wang Y.

Exp Biol Med (Maywood). 2016 Jan;241(1):79-89. doi: 10.1177/1535370215594584. Epub 2015 Jul 12.


[Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats].

Xu L, Ma S, Li P, Tang Q.

Zhong Yao Cai. 2004 May;27(5):348-51. Chinese.


Fusion of core pathways reveals a horizontal synergistic mechanism underlying combination therapy.

Wang Z, Jing ZW, Zhou CX, Zhang L, Cheng J, Zhang ZJ, Liu J, Xu CS, Li PT, Wang YY.

Eur J Pharmacol. 2011 Sep 30;667(1-3):278-86. doi: 10.1016/j.ejphar.2011.05.046. Epub 2011 Jun 1.


[Pharmacological evaluation of baicalin and jasminoidin and their combination on focal cerebral ischemia-reperfusion injury].

Zhang ZJ, Wang LY, Wang Z, Li PT, Wang YY.

Zhongguo Zhong Yao Za Zhi. 2006 Jun;31(11):907-10. Chinese.


Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.

Zhang Q, Fu X, Wang J, Yang M, Kong L.

Oxid Med Cell Longev. 2017;2017:9848594. doi: 10.1155/2017/9848594. Epub 2017 Aug 14.


Phenotype-dependent alteration of pathways and networks reveals a pure synergistic mechanism for compounds treating mouse cerebral ischemia.

Wang PQ, Li B, Liu J, Zhang YY, Yu YN, Zhang XX, Yuan Y, Guo ZL, Wu HL, Li HX, Dang HX, Guo SS, Wang Z.

Acta Pharmacol Sin. 2015 Jun;36(6):734-47. doi: 10.1038/aps.2014.168. Epub 2015 May 11.


Induced cortical neurogenesis after focal cerebral ischemia--Three active components from Huang-Lian-Jie-Du Decoction.

Zou H, Long J, Zhang Q, Zhao H, Bian B, Wang Y, Zhang J, Zhao H, Wang L.

J Ethnopharmacol. 2016 Feb 3;178:115-24. doi: 10.1016/j.jep.2015.12.001. Epub 2015 Dec 2.


Synergism and rules of the new combination drug Yiqijiedu formulae (YQJD) on ischemic stroke based on amino acids (AAs) metabolism.

Gao J, Chen C, Chen JX, Wen LM, Yang GL, Duan FP, Huang ZY, Li DF, Yu DR, Yang HJ, Li SJ.

Sci Rep. 2014 Jun 3;4:5149. doi: 10.1038/srep05149.


Spatiotemporal PET Imaging of Dynamic Metabolic Changes After Therapeutic Approaches of Induced Pluripotent Stem Cells, Neuronal Stem Cells, and a Chinese Patent Medicine in Stroke.

Zhang H, Song F, Xu C, Liu H, Wang Z, Li J, Wu S, YehuaShen, Chen Y, Zhu Y, Du R, Tian M.

J Nucl Med. 2015 Nov;56(11):1774-9. doi: 10.2967/jnumed.115.163170. Epub 2015 Sep 10.


Convergent and divergent pathways decoding hierarchical additive mechanisms in treating cerebral ischemia-reperfusion injury.

Zhang YY, Li HX, Chen YY, Fang H, Yu YN, Liu J, Jing ZW, Wang Z, Wang YY.

CNS Neurosci Ther. 2014 Mar;20(3):253-63. doi: 10.1111/cns.12205. Epub 2013 Dec 19.


[Optimal combination of baicalin, icariin and Astragalus saponin I from a Chinese herbal compound Biminne].

Gong WY, Zhang XM, Shen ZY, Hu GR, Zhang SQ, Liu RH, Zhang WD, Dong JC.

Zhong Xi Yi Jie He Xue Bao. 2010 Jun;8(6):541-7. Chinese.


Deciphering the pharmacological mechanism of the Chinese formula huanglian-jie-du decoction in the treatment of ischemic stroke using a systems biology-based strategy.

Zhang YQ, Wang SS, Zhu WL, Ma Y, Zhang FB, Liang RX, Xu HY, Yang HJ.

Acta Pharmacol Sin. 2015 Jun;36(6):724-33. doi: 10.1038/aps.2014.124. Epub 2015 May 4.

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