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Extension of chronological lifespan by ScEcl1 depends on mitochondria in Saccharomyces cerevisiae.

Azuma K, Ohtsuka H, Murakami H, Aiba H.

Biosci Biotechnol Biochem. 2012;76(10):1938-42. Epub 2012 Oct 7.


Identification and characterization of an Ecl1-family gene in Saccharomyces cerevisiae.

Azuma K, Ohtsuka H, Mita S, Murakami H, Aiba H.

Biosci Biotechnol Biochem. 2009 Dec;73(12):2787-9. Epub 2009 Dec 7.


Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins.

Smith DL Jr, McClure JM, Matecic M, Smith JS.

Aging Cell. 2007 Oct;6(5):649-62. Epub 2007 Aug 15.


Enhancement of mitochondrial function correlates with the extension of lifespan by caloric restriction and caloric restriction mimetics in yeast.

Choi KM, Lee HL, Kwon YY, Kang MS, Lee SK, Lee CK.

Biochem Biophys Res Commun. 2013 Nov 8;441(1):236-42. doi: 10.1016/j.bbrc.2013.10.049. Epub 2013 Oct 17.


Different carbon sources affect lifespan and protein redox state during Saccharomyces cerevisiae chronological ageing.

Magherini F, Carpentieri A, Amoresano A, Gamberi T, De Filippo C, Rizzetto L, Biagini M, Pucci P, Modesti A.

Cell Mol Life Sci. 2009 Mar;66(5):933-47. doi: 10.1007/s00018-009-8574-z.


hsf1 (+) extends chronological lifespan through Ecl1 family genes in fission yeast.

Ohtsuka H, Azuma K, Murakami H, Aiba H.

Mol Genet Genomics. 2011 Jan;285(1):67-77. doi: 10.1007/s00438-010-0588-6. Epub 2010 Nov 12.


Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism.

Tahara EB, Cunha FM, Basso TO, Della Bianca BE, Gombert AK, Kowaltowski AJ.

PLoS One. 2013;8(2):e56388. doi: 10.1371/journal.pone.0056388. Epub 2013 Feb 11.


Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan.

Schroeder EA, Shadel GS.

Mech Ageing Dev. 2014 Jan;135:41-9. doi: 10.1016/j.mad.2013.12.002. Epub 2013 Dec 25.


Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae.

Delaney JR, Murakami C, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, Kim JR, Klum S, Liao E, Lin MS, Lo W, Miller H, Moller R, Peng ZJ, Pollard T, Pradeep P, Pruett D, Rai D, Ros V, Schuster A, Singh M, Spector BL, Wende HV, Wang AM, Wasko BM, Olsen B, Kaeberlein M.

Exp Gerontol. 2013 Oct;48(10):1006-13. doi: 10.1016/j.exger.2012.12.001. Epub 2012 Dec 9.


Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae.

Barros MH, Bandy B, Tahara EB, Kowaltowski AJ.

J Biol Chem. 2004 Nov 26;279(48):49883-8. Epub 2004 Sep 21.


Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: common targets and prevention by calorie restriction.

Reverter-Branchat G, Cabiscol E, Tamarit J, Ros J.

J Biol Chem. 2004 Jul 23;279(30):31983-9. Epub 2004 May 27.


Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast.

Aerts AM, Zabrocki P, Govaert G, Mathys J, Carmona-Gutierrez D, Madeo F, Winderickx J, Cammue BP, Thevissen K.

FEBS Lett. 2009 Jan 5;583(1):113-7. doi: 10.1016/j.febslet.2008.11.028. Epub 2008 Dec 4.


Chronological lifespan extension by Ecl1 family proteins depends on Prr1 response regulator in fission yeast.

Ohtsuka H, Azuma K, Kubota S, Murakami H, Giga-Hama Y, Tohda H, Aiba H.

Genes Cells. 2012 Jan;17(1):39-52. doi: 10.1111/j.1365-2443.2011.01571.x.


Glutathione is necessary to ensure benefits of calorie restriction during ageing in Saccharomyces cerevisiae.

Mannarino SC, Amorim MA, Pereira MD, Moradas-Ferreira P, Panek AD, Costa V, Eleutherio EC.

Mech Ageing Dev. 2008 Dec;129(12):700-5. doi: 10.1016/j.mad.2008.09.001. Epub 2008 Sep 18.


Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence.

Kharade SV, Mittal N, Das SP, Sinha P, Roy N.

FEBS Lett. 2005 Dec 19;579(30):6809-13. Epub 2005 Nov 28.


Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction.

Ocampo A, Liu J, Schroeder EA, Shadel GS, Barrientos A.

Cell Metab. 2012 Jul 3;16(1):55-67. doi: 10.1016/j.cmet.2012.05.013.


ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiae.

Kitagaki H, Cowart LA, Matmati N, Montefusco D, Gandy J, de Avalos SV, Novgorodov SA, Zheng J, Obeid LM, Hannun YA.

J Biol Chem. 2009 Apr 17;284(16):10818-30. doi: 10.1074/jbc.M805029200. Epub 2009 Jan 29.


Mitochondria-mediated hormetic response in life span extension of calorie-restricted Saccharomyces cerevisiae.

Sharma PK, Agrawal V, Roy N.

Age (Dordr). 2011 Jun;33(2):143-54. doi: 10.1007/s11357-010-9169-1. Epub 2010 Jul 17.


An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast.

Hughes AL, Gottschling DE.

Nature. 2012 Dec 13;492(7428):261-5. doi: 10.1038/nature11654. Epub 2012 Nov 21.

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