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Items: 1 to 20 of 89

1.

Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells.

Koso H, Takeda H, Yew CC, Ward JM, Nariai N, Ueno K, Nagasaki M, Watanabe S, Rust AG, Adams DJ, Copeland NG, Jenkins NA.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):E2998-3007. doi: 10.1073/pnas.1215899109. Epub 2012 Oct 8.

2.
3.

Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry.

Tchorz JS, Tome M, Cloëtta D, Sivasankaran B, Grzmil M, Huber RM, Rutz-Schatzmann F, Kirchhoff F, Schaeren-Wiemers N, Gassmann M, Hemmings BA, Merlo A, Bettler B.

Cell Death Dis. 2012 Jun 21;3:e325. doi: 10.1038/cddis.2012.65.

4.

Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.

Friedmann-Morvinski D, Bushong EA, Ke E, Soda Y, Marumoto T, Singer O, Ellisman MH, Verma IM.

Science. 2012 Nov 23;338(6110):1080-4. doi: 10.1126/science.1226929. Epub 2012 Oct 18.

5.

Contact and encirclement of glioma cells in vitro is an intrinsic behavior of a clonal human neural stem cell line.

Khosh N, Brown CE, Aboody KS, Barish ME.

PLoS One. 2012;7(12):e51859. doi: 10.1371/journal.pone.0051859. Epub 2012 Dec 11.

6.

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.

Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA.

Cold Spring Harb Symp Quant Biol. 2008;73:427-37. doi: 10.1101/sqb.2008.73.047. Epub 2009 Jan 15.

PMID:
19150964
7.

Neural stem cells producing an inducible and soluble form of Gas1 target and inhibit intracranial glioma growth.

López-Ornelas A, Vergara P, Segovia J.

Cytotherapy. 2014 Jul;16(7):1011-23. doi: 10.1016/j.jcyt.2013.12.004. Epub 2014 Feb 12.

PMID:
24529556
8.

Isolation of cancer stem cells from adult glioblastoma multiforme.

Yuan X, Curtin J, Xiong Y, Liu G, Waschsmann-Hogiu S, Farkas DL, Black KL, Yu JS.

Oncogene. 2004 Dec 16;23(58):9392-400.

PMID:
15558011
9.

YB-1 bridges neural stem cells and brain tumor-initiating cells via its roles in differentiation and cell growth.

Fotovati A, Abu-Ali S, Wang PS, Deleyrolle LP, Lee C, Triscott J, Chen JY, Franciosi S, Nakamura Y, Sugita Y, Uchiumi T, Kuwano M, Leavitt BR, Singh SK, Jury A, Jones C, Wakimoto H, Reynolds BA, Pallen CJ, Dunn SE.

Cancer Res. 2011 Aug 15;71(16):5569-78. doi: 10.1158/0008-5472.CAN-10-2805. Epub 2011 Jul 5.

10.

The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.

Tobias AL, Thaci B, Auffinger B, Rincón E, Balyasnikova IV, Kim CK, Han Y, Zhang L, Aboody KS, Ahmed AU, Lesniak MS.

Stem Cells Transl Med. 2013 Sep;2(9):655-66. doi: 10.5966/sctm.2013-0039. Epub 2013 Aug 7.

11.

Identification of Sleeping Beauty transposon insertions in solid tumors using linker-mediated PCR.

Janik CL, Starr TK.

J Vis Exp. 2013 Feb 1;(72):e50156. doi: 10.3791/50156.

12.

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors.

Liu Q, Nguyen DH, Dong Q, Shitaku P, Chung K, Liu OY, Tso JL, Liu JY, Konkankit V, Cloughesy TF, Mischel PS, Lane TF, Liau LM, Nelson SF, Tso CL.

J Neurooncol. 2009 Aug;94(1):1-19. doi: 10.1007/s11060-009-9919-z. Epub 2009 May 26.

13.

GBM secretome induces transient transformation of human neural precursor cells.

Venugopal C, Wang XS, Manoranjan B, McFarlane N, Nolte S, Li M, Murty N, Siu KW, Singh SK.

J Neurooncol. 2012 Sep;109(3):457-66. doi: 10.1007/s11060-012-0917-1. Epub 2012 Jul 1.

PMID:
22752853
14.

Discovering gene-environment interactions in glioblastoma through a comprehensive data integration bioinformatics method.

Kunkle B, Yoo C, Roy D.

Neurotoxicology. 2013 Mar;35:1-14. doi: 10.1016/j.neuro.2012.11.001. Epub 2012 Dec 20.

PMID:
23261424
15.

Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen.

Friedel RH, Friedel CC, Bonfert T, Shi R, Rad R, Soriano P.

PLoS One. 2013 Aug 5;8(8):e72338. doi: 10.1371/journal.pone.0072338. Print 2013.

16.

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.

Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG.

BMC Med. 2008 Jun 24;6:14. doi: 10.1186/1741-7015-6-14.

17.

Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome.

Sandberg CJ, Altschuler G, Jeong J, Strømme KK, Stangeland B, Murrell W, Grasmo-Wendler UH, Myklebost O, Helseth E, Vik-Mo EO, Hide W, Langmoen IA.

Exp Cell Res. 2013 Aug 15;319(14):2230-43. doi: 10.1016/j.yexcr.2013.06.004. Epub 2013 Jun 18.

18.

Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish.

McGrail M, Hatler JM, Kuang X, Liao HK, Nannapaneni K, Watt KE, Uhl JD, Largaespada DA, Vollbrecht E, Scheetz TE, Dupuy AJ, Hostetter JM, Essner JJ.

PLoS One. 2011 Apr 21;6(4):e18826. doi: 10.1371/journal.pone.0018826.

19.

The identification of mitochondrial DNA variants in glioblastoma multiforme.

Yeung KY, Dickinson A, Donoghue JF, Polekhina G, White SJ, Grammatopoulos DK, McKenzie M, Johns TG, St John JC.

Acta Neuropathol Commun. 2014 Jan 2;2:1. doi: 10.1186/2051-5960-2-1.

20.

Mouse induced glioma-initiating cell models and therapeutic targets.

Kondo T.

Anticancer Agents Med Chem. 2010 Jul;10(6):471-80.

PMID:
20879984
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