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Items: 1 to 20 of 90

1.

Leptospira interrogans shotgun phage display identified LigB as a heparin-binding protein.

Ching AT, Fávaro RD, Lima SS, Chaves Ade A, de Lima MA, Nader HB, Abreu PA, Ho PL.

Biochem Biophys Res Commun. 2012 Nov 2;427(4):774-9. doi: 10.1016/j.bbrc.2012.09.137. Epub 2012 Oct 5.

2.

Evaluation of novel fusion proteins derived from extracellular matrix binding domains of LigB as vaccine candidates against leptospirosis in a hamster model.

Cao Y, Faisal SM, Yan W, Chang YC, McDonough SP, Zhang N, Akey BL, Chang YF.

Vaccine. 2011 Oct 6;29(43):7379-86. doi: 10.1016/j.vaccine.2011.07.070. Epub 2011 Jul 29.

PMID:
21803087
3.

Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen.

Choy HA, Kelley MM, Chen TL, Møller AK, Matsunaga J, Haake DA.

Infect Immun. 2007 May;75(5):2441-50. Epub 2007 Feb 12.

4.

Adhesin activity of Leptospira interrogans lipoprotein identified by in vivo and in vitro shotgun phage display.

Lima SS, Ching AT, Fávaro RD, Da Silva JB, Oliveira ML, Carvalho E, Abreu PA, Vasconcellos SA, Ho PL.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):342-7. doi: 10.1016/j.bbrc.2012.12.095. Epub 2013 Jan 3.

5.

A newly identified protein of Leptospira interrogans mediates binding to laminin.

Longhi MT, Oliveira TR, Romero EC, Gonçales AP, de Morais ZM, Vasconcellos SA, Nascimento AL.

J Med Microbiol. 2009 Oct;58(Pt 10):1275-82. doi: 10.1099/jmm.0.011916-0. Epub 2009 Jun 18.

PMID:
19541787
6.

The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans.

Choy HA, Kelley MM, Croda J, Matsunaga J, Babbitt JT, Ko AI, Picardeau M, Haake DA.

PLoS One. 2011 Feb 9;6(2):e16879. doi: 10.1371/journal.pone.0016879.

7.

Monoclonal antibodies against the leptospiral immunoglobulin-like proteins A and B conserved regions.

Monte LG, Conceição FR, Coutinho ML, Seixas FK, da Silva EF, Vasconcellos FA, deCastro LA, Hartleben CP, Dellagostin OA, Aleixo JA.

Comp Immunol Microbiol Infect Dis. 2011 Sep;34(5):441-6. doi: 10.1016/j.cimid.2011.08.003. Epub 2011 Sep 7.

PMID:
21903270
8.

Targeted mutagenesis in pathogenic Leptospira species: disruption of the LigB gene does not affect virulence in animal models of leptospirosis.

Croda J, Figueira CP, Wunder EA Jr, Santos CS, Reis MG, Ko AI, Picardeau M.

Infect Immun. 2008 Dec;76(12):5826-33. doi: 10.1128/IAI.00989-08. Epub 2008 Sep 22.

9.

Comparative subproteome analysis of three representative Leptospira interrogans vaccine strains reveals cross-reactive antigens and novel virulence determinants.

Zeng LB, Zhuang XR, Huang LL, Zhang YY, Chen CY, Dong K, Zhang Y, Cui ZL, Ding XL, Chang YF, Guo XK, Zhu YZ.

J Proteomics. 2015 Jan 1;112:27-37. doi: 10.1016/j.jprot.2014.08.015. Epub 2014 Sep 6.

PMID:
25201075
10.

Identification of cell-binding adhesins of Leptospira interrogans.

Evangelista KV, Hahn B, Wunder EA Jr, Ko AI, Haake DA, Coburn J.

PLoS Negl Trop Dis. 2014 Oct 2;8(10):e3215. doi: 10.1371/journal.pntd.0003215. eCollection 2014 Oct.

11.

Functional and immunological evaluation of two novel proteins of Leptospira spp.

Fernandes LG, Vieira ML, Alves IJ, de Morais ZM, Vasconcellos SA, Romero EC, Nascimento AL.

Microbiology. 2014 Jan;160(Pt 1):149-64. doi: 10.1099/mic.0.072074-0. Epub 2013 Oct 25.

PMID:
24162609
12.

Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection.

Atzingen MV, Barbosa AS, De Brito T, Vasconcellos SA, de Morais ZM, Lima DM, Abreu PA, Nascimento AL.

BMC Microbiol. 2008 Apr 29;8:70. doi: 10.1186/1471-2180-8-70.

13.

Characterization of leptospiral proteins that afford partial protection in hamsters against lethal challenge with Leptospira interrogans.

Atzingen MV, Gonçales AP, de Morais ZM, Araújo ER, De Brito T, Vasconcellos SA, Nascimento AL.

J Med Microbiol. 2010 Sep;59(Pt 9):1005-15. doi: 10.1099/jmm.0.021485-0. Epub 2010 Jun 17.

PMID:
20558583
14.

Identification and characterization of OmpA-like proteins as novel vaccine candidates for Leptospirosis.

Yan W, Faisal SM, McDonough SP, Chang CF, Pan MJ, Akey B, Chang YF.

Vaccine. 2010 Mar 8;28(11):2277-83. doi: 10.1016/j.vaccine.2009.12.071. Epub 2010 Jan 9.

PMID:
20064477
15.

Recombinant Mycobacterium bovis BCG expressing the LipL32 antigen of Leptospira interrogans protects hamsters from challenge.

Seixas FK, da Silva EF, Hartwig DD, Cerqueira GM, Amaral M, Fagundes MQ, Dossa RG, Dellagostin OA.

Vaccine. 2007 Dec 21;26(1):88-95. Epub 2007 Nov 12.

PMID:
18063449
16.

Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp.

Souza NM, Vieira ML, Alves IJ, de Morais ZM, Vasconcellos SA, Nascimento AL.

Microb Pathog. 2012 Sep;53(3-4):125-34. doi: 10.1016/j.micpath.2012.06.001. Epub 2012 Jun 23.

17.

Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model.

Yan W, Faisal SM, McDonough SP, Divers TJ, Barr SC, Chang CF, Pan MJ, Chang YF.

Microbes Infect. 2009 Feb;11(2):230-7. doi: 10.1016/j.micinf.2008.11.008. Epub 2008 Dec 3.

PMID:
19070678
18.

Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity.

Faisal SM, Yan W, McDonough SP, Chang YF.

Vaccine. 2009 Jan 14;27(3):378-87. doi: 10.1016/j.vaccine.2008.10.089. Epub 2008 Nov 18.

PMID:
19022317
19.
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