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Items: 1 to 20 of 109

1.

Fatty acids regulate endothelial lipase and inflammatory markers in macrophages and in mouse aorta: a role for PPARγ.

Jung UJ, Torrejon C, Chang CL, Hamai H, Worgall TS, Deckelbaum RJ.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2929-37. doi: 10.1161/ATVBAHA.112.300188. Epub 2012 Oct 4.

2.

Incremental replacement of saturated fats by n-3 fatty acids in high-fat, high-cholesterol diets reduces elevated plasma lipid levels and arterial lipoprotein lipase, macrophages and atherosclerosis in LDLR-/- mice.

Chang CL, Torrejon C, Jung UJ, Graf K, Deckelbaum RJ.

Atherosclerosis. 2014 Jun;234(2):401-9. doi: 10.1016/j.atherosclerosis.2014.03.022. Epub 2014 Apr 3.

3.
4.

Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.

Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH.

Atherosclerosis. 2009 May;204(1):147-55. doi: 10.1016/j.atherosclerosis.2008.08.024. Epub 2008 Sep 2.

5.

Eicosapentaenoic acid inhibits interleukin-6 production in interleukin-1beta-stimulated C6 glioma cells through peroxisome proliferator-activated receptor-gamma.

Kawashima A, Harada T, Imada K, Yano T, Mizuguchi K.

Prostaglandins Leukot Essent Fatty Acids. 2008 Jul-Aug;79(1-2):59-65. doi: 10.1016/j.plefa.2008.07.002. Epub 2008 Aug 30.

PMID:
18762411
6.

Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor gamma and nuclear factor-kappaB in macrophages.

Necela BM, Su W, Thompson EA.

Immunology. 2008 Nov;125(3):344-58. doi: 10.1111/j.1365-2567.2008.02849.x. Epub 2008 Apr 18.

7.

Endothelial cell peroxisome proliferator-activated receptor γ reduces endotoxemic pulmonary inflammation and injury.

Reddy AT, Lakshmi SP, Kleinhenz JM, Sutliff RL, Hart CM, Reddy RC.

J Immunol. 2012 Dec 1;189(11):5411-20. doi: 10.4049/jimmunol.1201487. Epub 2012 Oct 26.

8.

Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.

Ishii N, Matsumura T, Kinoshita H, Fukuda K, Motoshima H, Senokuchi T, Nakao S, Tsutsumi A, Kim-Mitsuyama S, Kawada T, Takeya M, Miyamura N, Nishikawa T, Araki E.

Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1598-605. doi: 10.1161/ATVBAHA.109.202309. Epub 2010 May 27.

9.

Role of Nrf2 in suppressing LPS-induced inflammation in mouse peritoneal macrophages by polyunsaturated fatty acids docosahexaenoic acid and eicosapentaenoic acid.

Wang H, Khor TO, Saw CL, Lin W, Wu T, Huang Y, Kong AN.

Mol Pharm. 2010 Dec 6;7(6):2185-93. doi: 10.1021/mp100199m. Epub 2010 Oct 6.

PMID:
20831192
10.
11.

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ.

Draper E, Reynolds CM, Canavan M, Mills KH, Loscher CE, Roche HM.

J Nutr Biochem. 2011 Aug;22(8):784-90. doi: 10.1016/j.jnutbio.2010.06.009. Epub 2010 Nov 26.

PMID:
21111596
12.

Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages.

Jin J, Zhang X, Lu Z, Perry DM, Li Y, Russo SB, Cowart LA, Hannun YA, Huang Y.

Am J Physiol Endocrinol Metab. 2013 Oct 1;305(7):E853-67. doi: 10.1152/ajpendo.00251.2013. Epub 2013 Aug 6.

13.

AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids.

Namgaladze D, Kemmerer M, von Knethen A, Brüne B.

Cardiovasc Res. 2013 Jun 1;98(3):479-87. doi: 10.1093/cvr/cvt073. Epub 2013 Mar 25.

PMID:
23531513
14.

FABP4 inhibition suppresses PPARγ activity and VLDL-induced foam cell formation in IL-4-polarized human macrophages.

Boss M, Kemmerer M, Brüne B, Namgaladze D.

Atherosclerosis. 2015 Jun;240(2):424-30. doi: 10.1016/j.atherosclerosis.2015.03.042. Epub 2015 Apr 3.

PMID:
25897794
15.

Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages.

Yasuda T, Hirata K, Ishida T, Kojima Y, Tanaka H, Okada T, Quertermous T, Yokoyama M.

J Atheroscler Thromb. 2007 Aug;14(4):192-201. Epub 2007 Aug 29.

16.

Antiatherosclerotic effect of farnesoid X receptor.

Mencarelli A, Renga B, Distrutti E, Fiorucci S.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H272-81. doi: 10.1152/ajpheart.01075.2008. Epub 2008 Nov 21.

17.

Stearidonic and eicosapentaenoic acids inhibit interleukin-6 expression in ob/ob mouse adipose stem cells via Toll-like receptor-2-mediated pathways.

Hsueh HW, Zhou Z, Whelan J, Allen KG, Moustaid-Moussa N, Kim H, Claycombe KJ.

J Nutr. 2011 Jul;141(7):1260-6. doi: 10.3945/jn.110.132571. Epub 2011 May 11.

18.

Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms.

Nagy ZS, Czimmerer Z, Szanto A, Nagy L.

Immunobiology. 2013 Nov;218(11):1336-44. doi: 10.1016/j.imbio.2013.06.011. Epub 2013 Jul 1.

PMID:
23870825
19.

TLR4 antagonist attenuates atherogenesis in LDL receptor-deficient mice with diet-induced type 2 diabetes.

Lu Z, Zhang X, Li Y, Lopes-Virella MF, Huang Y.

Immunobiology. 2015 Nov;220(11):1246-54. doi: 10.1016/j.imbio.2015.06.016. Epub 2015 Jun 30.

20.

Lipid synthesis in macrophages during inflammation in vivo: effect of agonists of peroxisome proliferator activated receptors alpha and gamma and of retinoid X receptors.

Posokhova EN, Khoshchenko OM, Chasovskikh MI, Pivovarova EN, Dushkin MI.

Biochemistry (Mosc). 2008 Mar;73(3):296-304.

PMID:
18393765

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