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Items: 1 to 20 of 55

1.

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

Majmudar CY, Højfeldt JW, Arevang CJ, Pomerantz WC, Gagnon JK, Schultz PJ, Cesa LC, Doss CH, Rowe SP, Vásquez V, Tamayo-Castillo G, Cierpicki T, Brooks CL 3rd, Sherman DH, Mapp AK.

Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11258-62. doi: 10.1002/anie.201206815. Epub 2012 Oct 8.

2.

Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.

Chaikuad A, Lang S, Brennan PE, Temperini C, Fedorov O, Hollander J, Nachane R, Abell C, Müller S, Siegal G, Knapp S.

J Med Chem. 2016 Feb 25;59(4):1648-53. doi: 10.1021/acs.jmedchem.5b01719. Epub 2016 Jan 13.

3.

Inhibition of lysine acetyltransferase KAT3B/p300 activity by a naturally occurring hydroxynaphthoquinone, plumbagin.

Ravindra KC, Selvi BR, Arif M, Reddy BA, Thanuja GR, Agrawal S, Pradhan SK, Nagashayana N, Dasgupta D, Kundu TK.

J Biol Chem. 2009 Sep 4;284(36):24453-64. doi: 10.1074/jbc.M109.023861. Epub 2009 Jul 1.

4.

Dimeric structure of p300/CBP associated factor.

Shi S, Lin J, Cai Y, Yu J, Hong H, Ji K, Downey JS, Lu X, Chen R, Han J, Han A.

BMC Struct Biol. 2014 Jan 14;14:2. doi: 10.1186/1472-6807-14-2.

5.

Protein tyrosine phosphatase 1B inhibitory effects of depsidone and pseudodepsidone metabolites from the Antarctic lichen Stereocaulon alpinum.

Seo C, Sohn JH, Ahn JS, Yim JH, Lee HK, Oh H.

Bioorg Med Chem Lett. 2009 May 15;19(10):2801-3. doi: 10.1016/j.bmcl.2009.03.108. Epub 2009 Mar 26.

PMID:
19362837
6.

Molecular Basis for the Mechanism of Constitutive CBP/p300 Coactivator Recruitment by CRTC1-MAML2 and Its Implications in cAMP Signaling.

Clark MD, Kumar GS, Marcum R, Luo Q, Zhang Y, Radhakrishnan I.

Biochemistry. 2015 Sep 8;54(35):5439-46. doi: 10.1021/acs.biochem.5b00332. Epub 2015 Aug 21.

7.

Schistosoma mansoni CBP/p300 has a conserved domain structure and interacts functionally with the nuclear receptor SmFtz-F1.

Bertin B, Oger F, Cornette J, Caby S, Noël C, Capron M, Fantappie MR, Rumjanek FD, Pierce RJ.

Mol Biochem Parasitol. 2006 Apr;146(2):180-91. Epub 2006 Jan 6.

PMID:
16427147
8.

The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity.

Hansson ML, Popko-Scibor AE, Saint Just Ribeiro M, Dancy BM, Lindberg MJ, Cole PA, Wallberg AE.

Nucleic Acids Res. 2009 May;37(9):2996-3006. doi: 10.1093/nar/gkp163. Epub 2009 Mar 20.

9.

Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.

Morita H, Tsuchiya T, Kishibe K, Noya S, Shiro M, Hirasawa Y.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3679-81. doi: 10.1016/j.bmcl.2009.03.170. Epub 2009 May 12.

PMID:
19481447
11.

Differential binding modes of the bromodomains of CREB-binding protein (CBP) and p300 with acetylated MyoD.

Wei L, Jamonnak N, Choy J, Wang Z, Zheng W.

Biochem Biophys Res Commun. 2008 Apr 4;368(2):279-84. doi: 10.1016/j.bbrc.2008.01.071. Epub 2008 Jan 28.

12.
13.

Complementary PCAF-coenzyme A mutagenesis: chemoenzymatic synthesis of a novel enlarged coenzyme A analogue and evaluation of its biological activity.

Khim L, Han J, Willetts L, Brady K, Gillece P, Rached O, Thomas NR, Stylianou E.

Chembiochem. 2010 Oct 18;11(15):2100-3. doi: 10.1002/cbic.201000286. No abstract available.

PMID:
20821790
14.

Ordering a dynamic protein via a small-molecule stabilizer.

Wang N, Majmudar CY, Pomerantz WC, Gagnon JK, Sadowsky JD, Meagher JL, Johnson TK, Stuckey JA, Brooks CL 3rd, Wells JA, Mapp AK.

J Am Chem Soc. 2013 Mar 6;135(9):3363-6. doi: 10.1021/ja3122334. Epub 2013 Feb 22.

15.

Structural basis of CBP/p300 recruitment in leukemia induction by E2A-PBX1.

Denis CM, Chitayat S, Plevin MJ, Wang F, Thompson P, Liu S, Spencer HL, Ikura M, LeBrun DP, Smith SP.

Blood. 2012 Nov 8;120(19):3968-77. doi: 10.1182/blood-2012-02-411397. Epub 2012 Sep 12.

16.

Negative regulation of transcription coactivator p300 by orphan receptor TR3.

Li GD, Fang JX, Chen HZ, Luo J, Zheng ZH, Shen YM, Wu Q.

Nucleic Acids Res. 2007;35(21):7348-59. Epub 2007 Oct 25.

17.

Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300.

Denis CM, Langelaan DN, Kirlin AC, Chitayat S, Munro K, Spencer HL, LeBrun DP, Smith SP.

Nucleic Acids Res. 2014 Jun;42(11):7370-82. doi: 10.1093/nar/gku206. Epub 2014 Mar 20.

18.
19.

Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.

Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13260-5. doi: 10.1073/pnas.0906770106. Epub 2009 Jul 27.

20.

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP.

Crump NT, Hazzalin CA, Bowers EM, Alani RM, Cole PA, Mahadevan LC.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7814-9. doi: 10.1073/pnas.1100099108. Epub 2011 Apr 25.

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