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67 kDa laminin receptor: structure, function and role in cancer and infection.

Rea VE, Rossi FW, De Paulis A, Ragno P, Selleri C, Montuori N.

Infez Med. 2012;20 Suppl 2:8-12. Review.


The 67 kDa laminin receptor: structure, function and role in disease.

Nelson J, McFerran NV, Pivato G, Chambers E, Doherty C, Steele D, Timson DJ.

Biosci Rep. 2008 Feb;28(1):33-48. doi: 10.1042/BSR20070004. Review.


Role of the 37 kDa laminin receptor precursor in the life cycle of prions.

Rieger R, Lasmézas CI, Weiss S.

Transfus Clin Biol. 1999 Feb;6(1):7-16. Review.


The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution.

Ardini E, Pesole G, Tagliabue E, Magnifico A, Castronovo V, Sobel ME, Colnaghi MI, Ménard S.

Mol Biol Evol. 1998 Aug;15(8):1017-25.


Formation of the 67-kDa laminin receptor by acylation of the precursor.

Butò S, Tagliabue E, Ardini E, Magnifico A, Ghirelli C, van den Brûle F, Castronovo V, Colnaghi MI, Sobel ME, Ménard S.

J Cell Biochem. 1998 Jun 1;69(3):244-51.


Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion.

Pesapane A, Di Giovanni C, Rossi FW, Alfano D, Formisano L, Ragno P, Selleri C, Montuori N, Lavecchia A.

Oncotarget. 2015 Jul 20;6(20):18116-33.


Expression of the 67-kDa laminin receptor in acute myeloid leukemia cells mediates adhesion to laminin and is frequently associated with monocytic differentiation.

Montuori N, Selleri C, Risitano AM, Raiola AM, Ragno P, Del Vecchio L, Rotoli B, Rossi G.

Clin Cancer Res. 1999 Jun;5(6):1465-72.


Interactions of the 67 kDa laminin receptor and its precursor with laminin.

Fatehullah A, Doherty C, Pivato G, Allen G, Devine L, Nelson J, Timson DJ.

Biosci Rep. 2009 Nov 10;30(2):73-9. doi: 10.1042/BSR20090023.


The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1.

Berno V, Porrini D, Castiglioni F, Campiglio M, Casalini P, Pupa SM, Balsari A, Ménard S, Tagliabue E.

Endocr Relat Cancer. 2005 Jun;12(2):393-406.


Protein synthesis is required for laminin-induced expression of the 67-kDa laminin receptor and its 37-kDa precursor.

Romanov VI, Wrathall LS, Simmons TD, Pinto da Silva P, Sobel ME.

Biochem Biophys Res Commun. 1995 Mar 17;208(2):637-43.


Green tea polyphenol EGCG sensing motif on the 67-kDa laminin receptor.

Fujimura Y, Sumida M, Sugihara K, Tsukamoto S, Yamada K, Tachibana H.

PLoS One. 2012;7(5):e37942. doi: 10.1371/journal.pone.0037942.


Hypoxia promotes metastasis in human gastric cancer by up-regulating the 67-kDa laminin receptor.

Liu L, Sun L, Zhao P, Yao L, Jin H, Liang S, Wang Y, Zhang D, Pang Y, Shi Y, Chai N, Zhang H, Zhang H.

Cancer Sci. 2010 Jul;101(7):1653-60. doi: 10.1111/j.1349-7006.2010.01592.x.


The metastasis-associated 67-kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization.

Selleri C, Ragno P, Ricci P, Visconte V, Scarpato N, Carriero MV, Rotoli B, Rossi G, Montuori N.

Blood. 2006 Oct 1;108(7):2476-84.


Structure-function studies of the functional and binding epitope of the human 37 kDa laminin receptor precursor protein.

Jaseja M, Mergen L, Gillette K, Forbes K, Sehgal I, Copié V.

J Pept Res. 2005 Jul;66(1):9-18.


The 67 kDa laminin receptor as a prognostic factor in human cancer.

Ménard S, Tagliabue E, Colnaghi MI.

Breast Cancer Res Treat. 1998;52(1-3):137-45. Review.


New insights into biological targets and therapeutic management of infectious diseases.

Selleri C, Zeppa P, Montuori N, Esposito S.

Infez Med. 2012;20 Suppl 2:5-7. No abstract available.


PED/PEA-15 interacts with the 67 kD laminin receptor and regulates cell adhesion, migration, proliferation and apoptosis.

Formisano P, Ragno P, Pesapane A, Alfano D, Alberobello AT, Rea VE, Giusto R, Rossi FW, Beguinot F, Rossi G, Montuori N.

J Cell Mol Med. 2012 Jul;16(7):1435-46. doi: 10.1111/j.1582-4934.2011.01411.x.


Identification of a novel function for 67-kDa laminin receptor: increase in laminin degradation rate and release of motility fragments.

Ardini E, Sporchia B, Pollegioni L, Modugno M, Ghirelli C, Castiglioni F, Tagliabue E, Ménard S.

Cancer Res. 2002 Mar 1;62(5):1321-5.

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