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Items: 1 to 20 of 116

1.

The transcriptional targets of mutant FOXL2 in granulosa cell tumours.

Rosario R, Araki H, Print CG, Shelling AN.

PLoS One. 2012;7(9):e46270. doi: 10.1371/journal.pone.0046270. Epub 2012 Sep 28.

2.

Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.

Fleming NI, Knower KC, Lazarus KA, Fuller PJ, Simpson ER, Clyne CD.

PLoS One. 2010 Dec 20;5(12):e14389. doi: 10.1371/journal.pone.0014389.

3.

The role of FOXL2 in the pathogenesis of adult ovarian granulosa cell tumours.

Rosario R, Cohen PA, Shelling AN.

Gynecol Oncol. 2014 May;133(2):382-7. doi: 10.1016/j.ygyno.2013.12.012. Epub 2013 Dec 14. Review.

PMID:
24342437
4.
5.

Comparative study of microRNA regulation on FOXL2 between adult-type and juvenile-type granulosa cell tumours in vitro.

Rosario R, Blenkiron C, Shelling AN.

Gynecol Oncol. 2013 Apr;129(1):209-15. doi: 10.1016/j.ygyno.2012.12.034. Epub 2012 Dec 30.

PMID:
23280087
6.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG.

N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542. Epub 2009 Jun 10.

7.

Adult granulosa cell tumours (GCT): clinicopathological outcomes including FOXL2 mutational status and expression.

Rosario R, Wilson M, Cheng WT, Payne K, Cohen PA, Fong P, Shelling AN.

Gynecol Oncol. 2013 Nov;131(2):325-9. doi: 10.1016/j.ygyno.2013.08.031. Epub 2013 Sep 2.

PMID:
24007948
8.

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W).

Kim JH, Yoon S, Park M, Park HO, Ko JJ, Lee K, Bae J.

Oncogene. 2011 Apr 7;30(14):1653-63. doi: 10.1038/onc.2010.541. Epub 2010 Nov 29.

PMID:
21119601
9.

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary.

Jamieson S, Butzow R, Andersson N, Alexiadis M, Unkila-Kallio L, Heikinheimo M, Fuller PJ, Anttonen M.

Mod Pathol. 2010 Nov;23(11):1477-85. doi: 10.1038/modpathol.2010.145. Epub 2010 Aug 6.

10.

A current perspective on the pathological assessment of FOXL2 in adult-type granulosa cell tumours of the ovary.

Kommoss S, Gilks CB, Penzel R, Herpel E, Mackenzie R, Huntsman D, Schirmacher P, Anglesio M, Schmidt D, Kommoss F.

Histopathology. 2014 Feb;64(3):380-8. doi: 10.1111/his.12253. Epub 2013 Nov 6.

PMID:
24192202
11.

Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers.

Kim MS, Hur SY, Yoo NJ, Lee SH.

J Pathol. 2010 Jun;221(2):147-52. doi: 10.1002/path.2688.

PMID:
20198651
12.

FOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.

Anttonen M, Pihlajoki M, Andersson N, Georges A, L'hôte D, Vattulainen S, Färkkilä A, Unkila-Kallio L, Veitia RA, Heikinheimo M.

PLoS One. 2014 Jan 9;9(1):e85545. doi: 10.1371/journal.pone.0085545. eCollection 2014.

13.

Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

Benayoun BA, Caburet S, Dipietromaria A, Georges A, D'Haene B, Pandaranayaka PJ, L'Hôte D, Todeschini AL, Krishnaswamy S, Fellous M, De Baere E, Veitia RA.

PLoS One. 2010 Jan 20;5(1):e8789. doi: 10.1371/journal.pone.0008789.

14.

Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors.

Leung DT, Fuller PJ, Chu S.

Int J Biochem Cell Biol. 2016 Mar;72:51-4. doi: 10.1016/j.biocel.2016.01.003. Epub 2016 Jan 11. Review.

PMID:
26791928
15.

Nuclear receptor profiling of ovarian granulosa cell tumors.

Alexiadis M, Eriksson N, Jamieson S, Davis M, Drummond AE, Chu S, Clyne CD, Muscat GE, Fuller PJ.

Horm Cancer. 2011 Jun;2(3):157-69. doi: 10.1007/s12672-011-0069-3.

PMID:
21761343
16.

Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation.

Benayoun BA, Anttonen M, L'Hôte D, Bailly-Bechet M, Andersson N, Heikinheimo M, Veitia RA.

Oncogene. 2013 May 30;32(22):2739-46. doi: 10.1038/onc.2012.298. Epub 2012 Jul 16.

PMID:
22797072
17.

Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors.

Hes O, Vaněček T, Petersson F, Grossmann P, Hora M, Perez Montiel DM, Steiner P, Dvořák M, Michal M.

Appl Immunohistochem Mol Morphol. 2011 Jul;19(4):347-51. doi: 10.1097/PAI.0b013e3182039ef2.

PMID:
21293260
18.

Mouse forkhead L2 maintains repression of FSH-dependent genes in the granulosa cell.

Kuo FT, Fan K, Bentsi-Barnes I, Barlow GM, Pisarska MD.

Reproduction. 2012 Oct;144(4):485-94. doi: 10.1530/REP-11-0259. Epub 2012 Jul 30.

19.

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.

Schrader KA, Gorbatcheva B, Senz J, Heravi-Moussavi A, Melnyk N, Salamanca C, Maines-Bandiera S, Cooke SL, Leung P, Brenton JD, Gilks CB, Monahan J, Huntsman DG.

PLoS One. 2009 Nov 24;4(11):e7988. doi: 10.1371/journal.pone.0007988.

20.

FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development.

Liu Z, Ren YA, Pangas SA, Adams J, Zhou W, Castrillon DH, Wilhelm D, Richards JS.

Mol Endocrinol. 2015 Jul;29(7):1006-24. doi: 10.1210/me.2015-1103. Epub 2015 Jun 10.

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