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Items: 1 to 20 of 153

1.

Distinct licensing of IL-18 and IL-1β secretion in response to NLRP3 inflammasome activation.

Schmidt RL, Lenz LL.

PLoS One. 2012;7(9):e45186. doi: 10.1371/journal.pone.0045186. Epub 2012 Sep 18.

2.

Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts.

Zhang A, Wang P, Ma X, Yin X, Li J, Wang H, Jiang W, Jia Q, Ni L.

Mol Immunol. 2015 Aug;66(2):253-62. doi: 10.1016/j.molimm.2015.03.009. Epub 2015 Apr 2.

3.

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.

Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR.

J Biol Chem. 2015 Aug 14;290(33):20167-84. doi: 10.1074/jbc.M115.652321. Epub 2015 Jun 22.

4.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
5.

Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway.

Li X, Liu S, Luo J, Liu A, Tang S, Liu S, Yu M, Zhang Y.

Pathog Dis. 2015 Jun;73(4). pii: ftu024. doi: 10.1093/femspd/ftu024. Epub 2015 Jan 5.

PMID:
25834143
6.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099. Epub 2010 Nov 3.

7.

The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells.

Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, Conforti-Andreoni C, Liang Qian H, Teng GG, Ricciardi-Castagnoli P, Mortellaro A.

Eur J Immunol. 2013 Aug;43(8):2126-37. doi: 10.1002/eji.201242918. Epub 2013 May 24.

8.

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S.

PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6.

9.

Methylsulfonylmethane inhibits NLRP3 inflammasome activation.

Ahn H, Kim J, Lee MJ, Kim YJ, Cho YW, Lee GS.

Cytokine. 2015 Feb;71(2):223-31. doi: 10.1016/j.cyto.2014.11.001. Epub 2014 Nov 21.

PMID:
25461402
10.

Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.

Abdalla H, Srinivasan L, Shah S, Mayer-Barber KD, Sher A, Sutterwala FS, Briken V.

PLoS One. 2012;7(7):e40722. doi: 10.1371/journal.pone.0040722. Epub 2012 Jul 24.

11.

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.

Zheng Q, Ren Y, Reinach PS, Xiao B, Lu H, Zhu Y, Qu J, Chen W.

Exp Eye Res. 2015 May;134:133-40. doi: 10.1016/j.exer.2015.02.013. Epub 2015 Feb 18.

PMID:
25701684
12.

NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx.

Katsnelson MA, Lozada-Soto KM, Russo HM, Miller BA, Dubyak GR.

Am J Physiol Cell Physiol. 2016 Jul 1;311(1):C83-C100. doi: 10.1152/ajpcell.00298.2015. Epub 2016 May 11.

13.

Lipopolysaccharide/adenosine triphosphate induces IL‑1β and IL-18 secretion through the NLRP3 inflammasome in RAW264.7 murine macrophage cells.

Xie Q, Shen WW, Zhong J, Huang C, Zhang L, Li J.

Int J Mol Med. 2014 Jul;34(1):341-9. doi: 10.3892/ijmm.2014.1755. Epub 2014 Apr 24.

PMID:
24789624
14.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

15.

Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.

Laudisi F, Spreafico R, Evrard M, Hughes TR, Mandriani B, Kandasamy M, Morgan BP, Sivasankar B, Mortellaro A.

J Immunol. 2013 Aug 1;191(3):1006-10. doi: 10.4049/jimmunol.1300489. Epub 2013 Jul 1.

16.

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G.

J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7.

18.

The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.

Moriwaki K, Farias Luz N, Balaji S, De Rosa MJ, O'Donnell CL, Gough PJ, Bertin J, Welsh RM, Chan FK.

J Immunol. 2016 Jan 1;196(1):407-15. doi: 10.4049/jimmunol.1501662. Epub 2015 Nov 18.

19.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S.

PLoS One. 2012;7(1):e29695. doi: 10.1371/journal.pone.0029695. Epub 2012 Jan 25.

20.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

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