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Items: 1 to 20 of 114

1.

Anti-angiogenic effects of thioridazine involving the FAK-mTOR pathway.

Byun HJ, Lee JH, Kim BR, Kang S, Dong SM, Park MS, Lee SH, Park SH, Rho SB.

Microvasc Res. 2012 Nov;84(3):227-34. doi: 10.1016/j.mvr.2012.09.006. Epub 2012 Sep 26.

PMID:
23022044
2.

Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

Huang SW, Lien JC, Kuo SC, Huang TF.

Carcinogenesis. 2012 May;33(5):1022-30. doi: 10.1093/carcin/bgs127. Epub 2012 Mar 20.

PMID:
22436611
3.

Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway.

He L, Wu Y, Lin L, Wang J, Wu Y, Chen Y, Yi Z, Liu M, Pang X.

Cancer Sci. 2011 Jan;102(1):219-25. doi: 10.1111/j.1349-7006.2010.01778.x. Epub 2010 Nov 19.

5.

Extracellular taurine induces angiogenesis by activating ERK-, Akt-, and FAK-dependent signal pathways.

Baek YY, Cho DH, Choe J, Lee H, Jeoung D, Ha KS, Won MH, Kwon YG, Kim YM.

Eur J Pharmacol. 2012 Jan 15;674(2-3):188-99. doi: 10.1016/j.ejphar.2011.11.022. Epub 2011 Nov 23.

PMID:
22130357
6.

Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo.

Zhong ZF, Hoi PM, Wu GS, Xu ZT, Tan W, Chen XP, Cui L, Wu T, Wang YT.

J Ethnopharmacol. 2012 Jun 1;141(2):721-7. doi: 10.1016/j.jep.2011.08.052. Epub 2011 Sep 3.

PMID:
21911050
8.

Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells.

Kang S, Dong SM, Kim BR, Park MS, Trink B, Byun HJ, Rho SB.

Apoptosis. 2012 Sep;17(9):989-97. doi: 10.1007/s10495-012-0717-2.

9.

Liquiritigenin inhibits serum-induced HIF-1α and VEGF expression via the AKT/mTOR-p70S6K signalling pathway in HeLa cells.

Xie SR, Wang Y, Liu CW, Luo K, Cai YQ.

Phytother Res. 2012 Aug;26(8):1133-41. doi: 10.1002/ptr.3696. Epub 2011 Dec 14.

PMID:
22170854
10.

Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts.

Park MS, Dong SM, Kim BR, Seo SH, Kang S, Lee EJ, Lee SH, Rho SB.

Oncotarget. 2014 Jul 15;5(13):4929-34.

11.

Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway.

Jiang WG, Ye L, Ji K, Frewer N, Ji J, Mason MD.

Int J Oncol. 2012 Nov;41(5):1635-42. doi: 10.3892/ijo.2012.1627. Epub 2012 Sep 11.

PMID:
22971748
12.

Programmed cell death 6 (PDCD6) inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of VEGFR-2.

Rho SB, Song YJ, Lim MC, Lee SH, Kim BR, Park SY.

Cell Signal. 2012 Jan;24(1):131-9. doi: 10.1016/j.cellsig.2011.08.013. Epub 2011 Aug 26.

PMID:
21893193
13.
14.

Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin αVβ3-FAK cascade.

Matsuda S, Fujita T, Kajiya M, Takeda K, Shiba H, Kawaguchi H, Kurihara H.

J Cell Physiol. 2012 May;227(5):2123-9. doi: 10.1002/jcp.22942.

PMID:
21769870
15.

MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation.

Kim BR, Lee SH, Park MS, Seo SH, Park YM, Kwon YJ, Rho SB.

Oncol Rep. 2016 Feb;35(2):1041-8. doi: 10.3892/or.2015.4408. Epub 2015 Nov 10.

PMID:
26555156
16.

Vitronectin-αvβ3 integrin engagement directs hypoxia-resistant mTOR activity and sustained protein synthesis linked to invasion by breast cancer cells.

Pola C, Formenti SC, Schneider RJ.

Cancer Res. 2013 Jul 15;73(14):4571-8. doi: 10.1158/0008-5472.CAN-13-0218. Epub 2013 May 30.

17.

Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis.

Chu PY, Huang LY, Hsu CH, Liang CC, Guan JL, Hung TH, Shen TL.

J Biol Chem. 2009 Jul 24;284(30):20215-26. doi: 10.1074/jbc.M109.018259. Epub 2009 May 27.

19.

Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.

Koul D, Shen R, Bergh S, Lu Y, de Groot JF, Liu TJ, Mills GB, Yung WK.

Mol Cancer Ther. 2005 Nov;4(11):1681-8.

20.

Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells.

Kim GD, Oh J, Jeong LS, Lee SK.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):79-86. doi: 10.1016/j.bbrc.2013.06.040. Epub 2013 Jun 21.

PMID:
23791876

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