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Items: 1 to 20 of 128

1.

Rebamipide ameliorates indomethacin-induced small intestinal injury in rats via the inhibition of matrix metalloproteinases activity.

Yamada S, Naito Y, Takagi T, Mizushima K, Horie R, Fukumoto K, Inoue K, Harusato A, Uchiyama K, Handa O, Yagi N, Ichikawa H, Yoshikawa T.

J Gastroenterol Hepatol. 2012 Dec;27(12):1816-24. doi: 10.1111/j.1440-1746.2012.07275.x.

PMID:
23020299
2.

Rebamipide inhibits indomethacin-induced small intestinal injury: possible involvement of intestinal microbiota modulation by upregulation of α-defensin 5.

Tanigawa T, Watanabe T, Otani K, Nadatani Y, Ohkawa F, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T.

Eur J Pharmacol. 2013 Mar 15;704(1-3):64-9. doi: 10.1016/j.ejphar.2013.02.010. Epub 2013 Feb 18.

PMID:
23428631
3.

Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression.

Naito Y, Kajikawa H, Mizushima K, Shimozawa M, Kuroda M, Katada K, Takagi T, Handa O, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T.

Dig Dis Sci. 2005 Oct;50 Suppl 1:S104-12.

PMID:
16184411
4.

Rebamipide reduces indomethacin-induced gastric injury in mice via down-regulation of ICAM-1 expression.

Hiratsuka T, Futagami S, Shindo T, Hamamoto T, Ueki N, Suzuki K, Shinji Y, Kusunoki M, Shinoki K, Wada K, Miyake K, Gudis K, Tsukui T, Sakamoto C.

Dig Dis Sci. 2005 Oct;50 Suppl 1:S84-9.

PMID:
16184426
5.

Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.

Murakami K, Okajima K, Harada N, Isobe H, Okabe H.

Dig Dis Sci. 1998 Sep;43(9 Suppl):139S-142S.

PMID:
9753240
6.

Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells.

Nagano Y, Matsui H, Muramatsu M, Shimokawa O, Shibahara T, Yanaka A, Nakahara A, Matsuzaki Y, Tanaka N, Nakamura Y.

Dig Dis Sci. 2005 Oct;50 Suppl 1:S76-83.

PMID:
16184425
7.

Rebamipide has the potential to reduce the intensity of NSAID-induced small intestinal injury: a double-blind, randomized, controlled trial evaluated by capsule endoscopy.

Fujimori S, Takahashi Y, Gudis K, Seo T, Ehara A, Kobayashi T, Mitsui K, Yonezawa M, Tanaka S, Tatsuguchi A, Sakamoto C.

J Gastroenterol. 2011 Jan;46(1):57-64. doi: 10.1007/s00535-010-0332-3. Epub 2010 Oct 6.

PMID:
20924615
8.

A randomized, double-blinded, placebo-controlled, multicenter trial, healing effect of rebamipide in patients with low-dose aspirin and/or non-steroidal anti-inflammatory drug induced small bowel injury.

Kurokawa S, Katsuki S, Fujita T, Saitoh Y, Ohta H, Nishikawa K, Sato Y, Sato Y, Ohira K, Yamada M, Kato M.

J Gastroenterol. 2014 Feb;49(2):239-44. doi: 10.1007/s00535-013-0805-2. Epub 2013 Apr 18. Erratum in: J Gastroenterol. 2014 Feb;49(2):373.

PMID:
23595613
9.

Rebamipide Promotes the Regeneration of Aspirin-Induced Small-Intestine Mucosal Injury through Accumulation of β-Catenin.

Lai Y, Zhong W, Yu T, Xia ZS, Li JY, Ouyang H, Shan TD, Yang HS, Chen QK.

PLoS One. 2015 Jul 2;10(7):e0132031. doi: 10.1371/journal.pone.0132031. eCollection 2015.

10.

Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.

Satoh H, Amagase K, Takeuchi K.

J Pharmacol Exp Ther. 2014 Feb;348(2):227-35. doi: 10.1124/jpet.113.208991. Epub 2013 Nov 19.

11.

Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.

Mizoguchi H, Ogawa Y, Kanatsu K, Tanaka A, Kato S, Takeuchi K.

J Gastroenterol Hepatol. 2001 Oct;16(10):1112-9.

PMID:
11686837
12.

Zinc protects against indomethacin-induced damage in the rat small intestine.

Sivalingam N, Pichandi S, Chapla A, Dinakaran A, Jacob M.

Eur J Pharmacol. 2011 Mar 1;654(1):106-16. doi: 10.1016/j.ejphar.2010.12.014. Epub 2010 Dec 24.

PMID:
21185825
13.

Rebamipide protects against indomethacin-induced gastric mucosal injury in healthy volunteers in a double-blind, placebo-controlled study.

Naito Y, Yoshikawa T, Iinuma S, Yagi N, Matsuyama K, Boku Y, Fujii T, Yoshida N, Kondo M, Sasaki E.

Dig Dis Sci. 1998 Sep;43(9 Suppl):83S-89S.

PMID:
9753232
14.

Rebamipide protects small intestinal mucosal injuries caused by indomethacin by modulating intestinal microbiota and the gene expression in intestinal mucosa in a rat model.

Kurata S, Nakashima T, Osaki T, Uematsu N, Shibamori M, Sakurai K, Kamiya S.

J Clin Biochem Nutr. 2015 Jan;56(1):20-7. doi: 10.3164/jcbn.14-67. Epub 2014 Oct 4.

15.

Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID) induced lipid peroxidation by the manganese superoxide dismutase (MnSOD) overexpression in gastrointestinal epithelial cells.

Nagano Y, Matsui H, Shimokawa O, Hirayama A, Tamura M, Nakamura Y, Kaneko T, Rai K, Indo HP, Majima HJ, Hyodo I.

J Physiol Pharmacol. 2012 Apr;63(2):137-42.

16.

Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study.

Niwa Y, Nakamura M, Ohmiya N, Maeda O, Ando T, Itoh A, Hirooka Y, Goto H.

J Gastroenterol. 2008;43(4):270-6. doi: 10.1007/s00535-007-2155-4. Epub 2008 May 6.

PMID:
18458842
17.

Aspirin-induced small bowel injuries and the preventive effect of rebamipide.

Mizukami K, Murakami K, Abe T, Inoue K, Uchida M, Okimoto T, Kodama M, Fujioka T.

World J Gastroenterol. 2011 Dec 14;17(46):5117-22. doi: 10.3748/wjg.v17.i46.5117.

18.

Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats.

Kakimoto K, Takai S, Murano M, Ishida K, Yoda Y, Inoue T, Jin D, Umegaki E, Higuchi K.

J Pharmacol Exp Ther. 2010 Feb;332(2):684-9. doi: 10.1124/jpet.109.162933. Epub 2009 Dec 8.

19.

Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice.

Higashimura Y, Naito Y, Takagi T, Tanimura Y, Mizushima K, Harusato A, Fukui A, Yoriki H, Handa O, Ohnogi H, Yoshikawa T.

J Gastroenterol Hepatol. 2014 Feb;29(2):310-7. doi: 10.1111/jgh.12373.

PMID:
23980531
20.

Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats.

Yamamoto A, Itoh T, Nasu R, Nishida R.

World J Gastroenterol. 2014 Mar 14;20(10):2641-52. doi: 10.3748/wjg.v20.i10.2641.

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