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Items: 1 to 20 of 95

1.

Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligands.

Green NM, Moody KS, Debatis M, Marshak-Rothstein A.

J Biol Chem. 2012 Nov 16;287(47):39789-99. doi: 10.1074/jbc.M112.383000. Epub 2012 Sep 27.

2.

Upregulation of TLR7 and TLR3 gene expression in the lung of respiratory syncytial virus infected mice.

Huang S, Wei W, Yun Y.

Wei Sheng Wu Xue Bao. 2009 Feb;49(2):239-45.

PMID:
19445181
3.

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, Christensen SR, Shlomchik MJ, Viglianti GA, Rifkin IR, Marshak-Rothstein A.

J Exp Med. 2005 Nov 7;202(9):1171-7. Epub 2005 Oct 31.

4.

Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model.

Duffau P, Menn-Josephy H, Cuda CM, Dominguez S, Aprahamian TR, Watkins AA, Yasuda K, Monach P, Lafyatis R, Rice LM, Kenneth Haines G 3rd, Gravallese EM, Baum R, Richez C, Perlman H, Bonegio RG, Rifkin IR.

Arthritis Rheumatol. 2015 Dec;67(12):3146-57. doi: 10.1002/art.39321.

5.

Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.

Nündel K, Green NM, Shaffer AL, Moody KL, Busto P, Eilat D, Miyake K, Oropallo MA, Cancro MP, Marshak-Rothstein A.

J Immunol. 2015 Mar 15;194(6):2504-12. doi: 10.4049/jimmunol.1402425. Epub 2015 Feb 13.

6.

Enteric Viruses Ameliorate Gut Inflammation via Toll-like Receptor 3 and Toll-like Receptor 7-Mediated Interferon-β Production.

Yang JY, Kim MS, Kim E, Cheon JH, Lee YS, Kim Y, Lee SH, Seo SU, Shin SH, Choi SS, Kim B, Chang SY, Ko HJ, Bae JW, Kweon MN.

Immunity. 2016 Apr 19;44(4):889-900. doi: 10.1016/j.immuni.2016.03.009. Epub 2016 Apr 12.

7.

Differential tissue targeting of autoimmunity manifestations by autoantigen-associated Y RNAs.

Greidinger EL, Zang Y, Martinez L, Jaimes K, Nassiri M, Bejarano P, Barber GN, Hoffman RW.

Arthritis Rheum. 2007 May;56(5):1589-97.

8.

Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.

Jackson SW, Scharping NE, Kolhatkar NS, Khim S, Schwartz MA, Li QZ, Hudkins KL, Alpers CE, Liggitt D, Rawlings DJ.

J Immunol. 2014 May 15;192(10):4525-32. doi: 10.4049/jimmunol.1400098. Epub 2014 Apr 7.

9.

Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs.

Hackl D, Loschko J, Sparwasser T, Reindl W, Krug AB.

Eur J Immunol. 2011 May;41(5):1334-43. doi: 10.1002/eji.201041014.

10.

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.

Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S.

Science. 2006 Jun 16;312(5780):1669-72. Epub 2006 May 18.

11.

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.

Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K.

J Exp Med. 2009 Jun 8;206(6):1339-50. doi: 10.1084/jem.20082316. Epub 2009 May 18.

12.

The toll of too much TLR7.

Krieg AM.

Immunity. 2007 Nov;27(5):695-7. Review.

13.

Toll-like receptor 8 deletion accelerates autoimmunity in a mouse model of lupus through a Toll-like receptor 7-dependent mechanism.

Tran NL, Manzin-Lorenzi C, Santiago-Raber ML.

Immunology. 2015 May;145(1):60-70. doi: 10.1111/imm.12426.

14.

Regulation of autoreactive B cell responses to endogenous TLR ligands.

Avalos AM, Busconi L, Marshak-Rothstein A.

Autoimmunity. 2010 Feb;43(1):76-83. doi: 10.3109/08916930903374618. Review.

15.

UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.

Schamber-Reis BL, Petritus PM, Caetano BC, Martinez ER, Okuda K, Golenbock D, Scott P, Gazzinelli RT.

J Biol Chem. 2013 Mar 8;288(10):7127-36. doi: 10.1074/jbc.M112.407684. Epub 2013 Jan 16.

16.

Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF.

Yang H, Wei J, Zhang H, Lin L, Zhang W, He S.

BMC Cell Biol. 2009 May 9;10:37. doi: 10.1186/1471-2121-10-37.

17.

B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.

Weindel CG, Richey LJ, Bolland S, Mehta AJ, Kearney JF, Huber BT.

Autophagy. 2015;11(7):1010-24. doi: 10.1080/15548627.2015.1052206.

18.

Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.

Li X, Saitoh S, Shibata T, Tanimura N, Fukui R, Miyake K.

Int Immunol. 2015 Feb;27(2):83-94. doi: 10.1093/intimm/dxu086. Epub 2014 Sep 19.

PMID:
25239130
19.

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.

Giltiay NV, Chappell CP, Sun X, Kolhatkar N, Teal TH, Wiedeman AE, Kim J, Tanaka L, Buechler MB, Hamerman JA, Imanishi-Kari T, Clark EA, Elkon KB.

J Exp Med. 2013 Nov 18;210(12):2773-89. doi: 10.1084/jem.20122798. Epub 2013 Oct 21.

20.

TLR7 signaling exacerbates CNS autoimmunity through downregulation of Foxp3+ Treg cells.

Lalive PH, Benkhoucha M, Tran NL, Kreutzfeldt M, Merkler D, Santiago-Raber ML.

Eur J Immunol. 2014 Jan;44(1):46-57. doi: 10.1002/eji.201242985. Epub 2013 Oct 1.

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