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Items: 1 to 20 of 169

1.

Expression of the nuclear factor-κB inhibitor A20 is altered in the cystic fibrosis epithelium.

Kelly C, Williams MT, Mitchell K, Elborn JS, Ennis M, Schock BC.

Eur Respir J. 2013 Jun;41(6):1315-23. doi: 10.1183/09031936.00032412. Epub 2012 Sep 27.

2.

A20 overexpression inhibits lipopolysaccharide-induced NF-κB activation, TRAF6 and CD40 expression in rat peritoneal mesothelial cells.

Zou XL, Pei DA, Yan JZ, Xu G, Wu P.

Int J Mol Sci. 2014 Apr 17;15(4):6592-608. doi: 10.3390/ijms15046592.

3.

Cystic Fibrosis from Laboratory to Bedside: The Role of A20 in NF-κB-Mediated Inflammation.

Bannon A, Zhang SD, Schock BC, Ennis M.

Med Princ Pract. 2015;24(4):301-10. doi: 10.1159/000381423. Epub 2015 Apr 25. Review.

4.

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling.

Shembade N, Parvatiyar K, Harhaj NS, Harhaj EW.

EMBO J. 2009 Mar 4;28(5):513-22. doi: 10.1038/emboj.2008.285. Epub 2009 Jan 8.

5.

Expression of the inflammatory regulator A20 correlates with lung function in patients with cystic fibrosis.

Kelly C, Williams MT, Elborn JS, Ennis M, Schock BC.

J Cyst Fibros. 2013 Jul;12(4):411-5. doi: 10.1016/j.jcf.2012.10.009. Epub 2012 Nov 17.

6.

Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis.

Malcomson B, Wilson H, Veglia E, Thillaiyampalam G, Barsden R, Donegan S, El Banna A, Elborn JS, Ennis M, Kelly C, Zhang SD, Schock BC.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3725-34. doi: 10.1073/pnas.1520289113. Epub 2016 Jun 10.

7.

Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells.

Kelly C, Canning P, Buchanan PJ, Williams MT, Brown V, Gruenert DC, Elborn JS, Ennis M, Schock BC.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L371-82. doi: 10.1152/ajplung.00372.2011. Epub 2013 Jan 11.

8.

A20 is induced by Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 and blocks K13-induced nuclear factor-kappaB in a negative feedback manner.

Matta H, Gopalakrishnan R, Punj V, Yi H, Suo Y, Chaudhary PM.

J Biol Chem. 2011 Jun 17;286(24):21555-64. doi: 10.1074/jbc.M111.224048. Epub 2011 Apr 29.

9.

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.

Shembade N, Ma A, Harhaj EW.

Science. 2010 Feb 26;327(5969):1135-9. doi: 10.1126/science.1182364.

10.

A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation.

Oshima N, Ishihara S, Rumi MA, Aziz MM, Mishima Y, Kadota C, Moriyama I, Ishimura N, Amano Y, Kinoshita Y.

Clin Exp Immunol. 2010 Feb;159(2):185-98. doi: 10.1111/j.1365-2249.2009.04048.x. Epub 2009 Nov 12.

11.

Proinflammatory mediators alter expression of nuclear factor kappa B-regulating deubiquitinases in sinonasal epithelial cells.

Li P, Wang Y, Turner JH.

Int Forum Allergy Rhinol. 2015 Jul;5(7):583-9. doi: 10.1002/alr.21538. Epub 2015 Apr 24.

12.

Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20.

Sisto M, Barca A, Lofrumento DD, Lisi S.

Clin Exp Immunol. 2016 May;184(2):183-96. doi: 10.1111/cei.12764. Epub 2016 Feb 23.

13.

A20 inhibits toll-like receptor 2- and 4-mediated interleukin-8 synthesis in airway epithelial cells.

Gon Y, Asai Y, Hashimoto S, Mizumura K, Jibiki I, Machino T, Ra C, Horie T.

Am J Respir Cell Mol Biol. 2004 Sep;31(3):330-6. Epub 2004 May 13.

PMID:
15142865
14.

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

Düwel M, Welteke V, Oeckinghaus A, Baens M, Kloo B, Ferch U, Darnay BG, Ruland J, Marynen P, Krappmann D.

J Immunol. 2009 Jun 15;182(12):7718-28. doi: 10.4049/jimmunol.0803313.

15.

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM.

Nature. 2004 Aug 5;430(7000):694-9. Epub 2004 Jul 18.

PMID:
15258597
16.

Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.

Pranski EL, Van Sanford CD, Dalal NV, Orr AL, Karmali D, Cooper DS, Costa N, Heilman CJ, Gearing M, Lah JJ, Levey AI, Betarbet RS.

Neurosci Lett. 2012 Jun 27;520(1):104-9. doi: 10.1016/j.neulet.2012.05.043. Epub 2012 May 23.

17.

Aberrant Low Expression of A20 in Tumor Necrosis Factor-α-stimulated SLE Monocytes Mediates Sustained NF-κB Inflammatory Response.

Shi X, Qian T, Li M, Chen F, Chen Y, Hao F.

Immunol Invest. 2015;44(5):497-508. doi: 10.3109/08820139.2015.1037957.

PMID:
26107748
18.

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, Julkunen I, Hiscott J.

J Biol Chem. 2006 Jan 27;281(4):2095-103. Epub 2005 Nov 23.

19.

Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.

Lin SC, Chung JY, Lamothe B, Rajashankar K, Lu M, Lo YC, Lam AY, Darnay BG, Wu H.

J Mol Biol. 2008 Feb 15;376(2):526-40. doi: 10.1016/j.jmb.2007.11.092. Epub 2007 Dec 4.

20.

Zinc-suppressed inflammatory cytokines by induction of A20-mediated inhibition of nuclear factor-κB.

Prasad AS, Bao B, Beck FW, Sarkar FH.

Nutrition. 2011 Jul-Aug;27(7-8):816-23. doi: 10.1016/j.nut.2010.08.010. Epub 2010 Oct 29.

PMID:
21035309

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