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Items: 1 to 20 of 286

1.

Involvement of Akt2/protein kinase B β (PKBβ) in the 8-Cl-cAMP-induced cancer cell growth inhibition.

Choi KY, Ahn YH, Ahn HW, Cho YJ, Hong SH.

J Cell Physiol. 2013 Apr;228(4):890-902. doi: 10.1002/jcp.24240.

PMID:
23018889
2.

Involvement of AMP-activated protein kinase and p38 mitogen-activated protein kinase in 8-Cl-cAMP-induced growth inhibition.

Han JH, Ahn YH, Choi KY, Hong SH.

J Cell Physiol. 2009 Jan;218(1):104-12. doi: 10.1002/jcp.21573.

PMID:
18756496
4.

8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.

Lucchi S, Calebiro D, de Filippis T, Grassi ES, Borghi MO, Persani L.

PLoS One. 2011;6(6):e20785. doi: 10.1371/journal.pone.0020785. Epub 2011 Jun 10.

5.

The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells.

Kim WG, Choi HJ, Kim TY, Shong YK, Kim WB.

Korean J Intern Med. 2014 Jul;29(4):474-81. doi: 10.3904/kjim.2014.29.4.474. Epub 2014 Jun 27.

6.

Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation.

Ishii N, Matsumura T, Kinoshita H, Motoshima H, Kojima K, Tsutsumi A, Kawasaki S, Yano M, Senokuchi T, Asano T, Nishikawa T, Araki E.

J Biol Chem. 2009 Dec 11;284(50):34561-9. doi: 10.1074/jbc.M109.028043. Epub 2009 Oct 20.

7.
8.

SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.

Choi KY, Cho YJ, Kim JS, Ahn YH, Hong SH.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):673-8. doi: 10.1016/j.bbrc.2015.05.123. Epub 2015 Jun 1.

PMID:
26043699
9.

AICAR Enhances the Phagocytic Ability of Macrophages towards Apoptotic Cells through P38 Mitogen Activated Protein Kinase Activation Independent of AMP-Activated Protein Kinase.

Quan H, Kim JM, Lee HJ, Lee SH, Choi JI, Bae HB.

PLoS One. 2015 May 28;10(5):e0127885. doi: 10.1371/journal.pone.0127885. eCollection 2015.

10.
11.
12.

Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR).

Zhuge J.

Cell Biol Toxicol. 2009 Jun;25(3):253-63. doi: 10.1007/s10565-008-9075-9. Epub 2008 May 13.

PMID:
18473182
13.

Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells.

Baumann P, Mandl-Weber S, Emmerich B, Straka C, Schmidmaier R.

Exp Cell Res. 2007 Oct 1;313(16):3592-603. Epub 2007 Jul 4.

PMID:
17669398
14.

AMPK activation enhances PPARα activity to inhibit cardiac hypertrophy via ERK1/2 MAPK signaling pathway.

Meng R, Pei Z, Zhang A, Zhou Y, Cai X, Chen B, Liu G, Mai W, Wei J, Dong Y.

Arch Biochem Biophys. 2011 Jul;511(1-2):1-7. doi: 10.1016/j.abb.2011.04.010. Epub 2011 Apr 21.

PMID:
21530483
15.
16.

AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-beta-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway.

Chang MY, Ho FM, Wang JS, Kang HC, Chang Y, Ye ZX, Lin WW.

Biochem Pharmacol. 2010 Oct 15;80(8):1210-20. doi: 10.1016/j.bcp.2010.06.049. Epub 2010 Jul 6.

PMID:
20615388
17.

Rap1 and p38 MAPK mediate 8-chloro-cAMP-induced growth inhibition in mouse fibroblast DT cells.

Ahn YH, Han JH, Hong SH.

J Cell Physiol. 2006 Dec;209(3):1039-45.

PMID:
16972264
18.

The influence of the BRAF V600E mutation in thyroid cancer cell lines on the anticancer effects of 5-aminoimidazole-4-carboxamide-ribonucleoside.

Choi HJ, Kim TY, Chung N, Yim JH, Kim WG, Kim JA, Kim WB, Shong YK.

J Endocrinol. 2011 Oct;211(1):79-85. doi: 10.1530/JOE-11-0260. Epub 2011 Jul 27.

19.

Activation of AMP-kinase by AICAR induces apoptosis of DU-145 prostate cancer cells through generation of reactive oxygen species and activation of c-Jun N-terminal kinase.

Sauer H, Engel S, Milosevic N, Sharifpanah F, Wartenberg M.

Int J Oncol. 2012 Feb;40(2):501-8. doi: 10.3892/ijo.2011.1230. Epub 2011 Oct 13.

PMID:
22002081
20.

AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: a possible role for AMPK.

Du JH, Xu N, Song Y, Xu M, Lu ZZ, Han C, Zhang YY.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1139-44. Epub 2005 Oct 6.

PMID:
16229818

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