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Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.

Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16672-7. doi: 10.1073/pnas.1213802109. Epub 2012 Sep 10.


Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability.

Bose S, Heath CM, Shah PA, Alayyoubi M, Jardetzky TS, Lamb RA.

J Virol. 2013 Dec;87(24):13520-31. doi: 10.1128/JVI.02123-13. Epub 2013 Oct 2.


Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering.

Connolly SA, Leser GP, Jardetzky TS, Lamb RA.

J Virol. 2009 Nov;83(21):10857-68. doi: 10.1128/JVI.01191-09. Epub 2009 Aug 26.


Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein.

Yin HS, Paterson RG, Wen X, Lamb RA, Jardetzky TS.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9288-93. Epub 2005 Jun 17.


Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion.

Bissonnette ML, Donald JE, DeGrado WF, Jardetzky TS, Lamb RA.

J Mol Biol. 2009 Feb 13;386(1):14-36. doi: 10.1016/j.jmb.2008.12.029. Epub 2008 Dec 24.


Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form.

Wong JJ, Paterson RG, Lamb RA, Jardetzky TS.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1056-61. doi: 10.1073/pnas.1523303113. Epub 2015 Dec 28.


Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy.

Connolly SA, Leser GP, Yin HS, Jardetzky TS, Lamb RA.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17903-8. Epub 2006 Nov 8.


The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.

Zokarkar A, Lamb RA.

J Virol. 2012 Mar;86(5):2600-9. doi: 10.1128/JVI.06546-11. Epub 2011 Dec 14.


Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

Widjaja I, Rigter A, Jacobino S, van Kuppeveld FJ, Leenhouts K, Palomo C, Melero JA, Leusen JH, Haijema BJ, Rottier PJ, de Haan CA.

PLoS One. 2015 Jun 24;10(6):e0130829. doi: 10.1371/journal.pone.0130829. eCollection 2015.


Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins.

Song AS, Poor TA, Abriata LA, Jardetzky TS, Dal Peraro M, Lamb RA.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3844-51. doi: 10.1073/pnas.1608349113. Epub 2016 Jun 22.


Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies.

Welch BD, Paduch M, Leser GP, Bergman Z, Kors CA, Paterson RG, Jardetzky TS, Kossiakoff AA, Lamb RA.

J Virol. 2014 Oct;88(20):11713-25. doi: 10.1128/JVI.01707-14. Epub 2014 Aug 13.


Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation.

Yin HS, Wen X, Paterson RG, Lamb RA, Jardetzky TS.

Nature. 2006 Jan 5;439(7072):38-44.


The second receptor binding site of the globular head of the Newcastle disease virus hemagglutinin-neuraminidase activates the stalk of multiple paramyxovirus receptor binding proteins to trigger fusion.

Porotto M, Salah Z, DeVito I, Talekar A, Palmer SG, Xu R, Wilson IA, Moscona A.

J Virol. 2012 May;86(10):5730-41. doi: 10.1128/JVI.06793-11. Epub 2012 Mar 21.


On the stability of parainfluenza virus 5 F proteins.

Poor TA, Song AS, Welch BD, Kors CA, Jardetzky TS, Lamb RA.

J Virol. 2015 Mar;89(6):3438-41. doi: 10.1128/JVI.03221-14. Epub 2015 Jan 14.


Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.

Xu R, Palmer SG, Porotto M, Palermo LM, Niewiesk S, Wilson IA, Moscona A.

MBio. 2013 Oct 22;4(5):e00803-13. doi: 10.1128/mBio.00803-13.


Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain.

Welch BD, Yuan P, Bose S, Kors CA, Lamb RA, Jardetzky TS.

PLoS Pathog. 2013;9(8):e1003534. doi: 10.1371/journal.ppat.1003534. Epub 2013 Aug 8.

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