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Items: 1 to 20 of 133

2.

Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin.

Zhang MM, Gruszczynski P, Walewska A, Bulaj G, Olivera BM, Yoshikami D.

J Neurophysiol. 2010 Jul;104(1):88-97. doi: 10.1152/jn.00145.2010.

3.

Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7.

Thomas-Tran R, Du Bois J.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5856-61. doi: 10.1073/pnas.1603486113.

4.

Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule.

Penzotti JL, Fozzard HA, Lipkind GM, Dudley SC Jr.

Biophys J. 1998 Dec;75(6):2647-57.

5.
7.

Site-directed mutagenesis of the putative pore region of the rat IIA sodium channel.

Kontis KJ, Goldin AL.

Mol Pharmacol. 1993 Apr;43(4):635-44.

PMID:
8386312
9.
10.

Biophysical costs associated with tetrodotoxin resistance in the sodium channel pore of the garter snake, Thamnophis sirtalis.

Lee CH, Jones DK, Ahern C, Sarhan MF, Ruben PC.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2011 Jan;197(1):33-43. doi: 10.1007/s00359-010-0582-9.

PMID:
20820785
11.

The tetrodotoxin binding site is within the outer vestibule of the sodium channel.

Fozzard HA, Lipkind GM.

Mar Drugs. 2010 Feb 1;8(2):219-34. doi: 10.3390/md8020219. Review.

14.

muO conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2.

Leipold E, DeBie H, Zorn S, Borges A, Olivera BM, Terlau H, Heinemann SH.

Channels (Austin). 2007 Jul-Aug;1(4):253-62.

PMID:
18698149
15.
16.
17.

Mechanism of tetrodotoxin block and resistance in sodium channels.

Chen R, Chung SH.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):370-4. doi: 10.1016/j.bbrc.2014.02.115.

PMID:
24607901
18.

Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels.

Zhang MM, McArthur JR, Azam L, Bulaj G, Olivera BM, French RJ, Yoshikami D.

Channels (Austin). 2009 Jan-Feb;3(1):32-8.

19.

Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.

Herold KF, Nau C, Ouyang W, Hemmings HC Jr.

Anesthesiology. 2009 Sep;111(3):591-9. doi: 10.1097/ALN.0b013e3181af64d4.

20.

Kinetic basis for insensitivity to tetrodotoxin and saxitoxin in sodium channels of canine heart and denervated rat skeletal muscle.

Guo XT, Uehara A, Ravindran A, Bryant SH, Hall S, Moczydlowski E.

Biochemistry. 1987 Dec 1;26(24):7546-56.

PMID:
2447944

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