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Items: 1 to 20 of 101

1.

Gamma-aminobutyric acid binds to GABAb receptor to inhibit cholangiocarcinoma cells growth via the JAK/STAT3 pathway.

Huang Q, Zhu CL, Liu CH, Xie F, Zhu K, Hu SY.

Dig Dis Sci. 2013 Mar;58(3):734-43. doi: 10.1007/s10620-012-2382-2. Epub 2012 Sep 25.

PMID:
23007731
2.

[Molecular mechanism of γ-aminobutyric acid inhibitory on the growth of cholangiocarcinoma QBC939 cell line].

Zhu CL, Huang Q, Liu CH, Xie F, Zhu K.

Zhonghua Wai Ke Za Zhi. 2013 Mar;51(3):261-5. Chinese.

PMID:
23859331
3.

gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway.

Fava G, Marucci L, Glaser S, Francis H, De Morrow S, Benedetti A, Alvaro D, Venter J, Meininger C, Patel T, Taffetani S, Marzioni M, Summers R, Reichenbach R, Alpini G.

Cancer Res. 2005 Dec 15;65(24):11437-46.

4.

FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.

Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R, Pei T, Pan S, Jiang H, Liu L.

BMC Cancer. 2014 Oct 25;14:783. doi: 10.1186/1471-2407-14-783.

5.

Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells.

Isomoto H, Kobayashi S, Werneburg NW, Bronk SF, Guicciardi ME, Frank DA, Gores GJ.

Hepatology. 2005 Dec;42(6):1329-38.

PMID:
16317687
6.

Anti-tumor and anti-angiogenic effects of Fucoidan on prostate cancer: possible JAK-STAT3 pathway.

Rui X, Pan HF, Shao SL, Xu XM.

BMC Complement Altern Med. 2017 Aug 1;17(1):378. doi: 10.1186/s12906-017-1885-y.

7.

Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells.

Swiatek-Machado K, Mieczkowski J, Ellert-Miklaszewska A, Swierk P, Fokt I, Szymanski S, Skora S, Szeja W, Grynkiewicz G, Lesyng B, Priebe W, Kaminska B.

Cancer Biol Ther. 2012 Jun;13(8):657-70. doi: 10.4161/cbt.20083. Epub 2012 Jun 1.

PMID:
22555804
8.
9.

BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway.

Lund IV, Hu Y, Raol YH, Benham RS, Faris R, Russek SJ, Brooks-Kayal AR.

Sci Signal. 2008 Oct 14;1(41):ra9. doi: 10.1126/scisignal.1162396.

10.
11.

Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway.

Senggunprai L, Kukongviriyapan V, Prawan A, Kukongviriyapan U.

Phytother Res. 2014 Jun;28(6):841-8. doi: 10.1002/ptr.5061. Epub 2013 Aug 30.

PMID:
24038588
12.

Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.

Gritsina G, Xiao F, O'Brien SW, Gabbasov R, Maglaty MA, Xu RH, Thapa RJ, Zhou Y, Nicolas E, Litwin S, Balachandran S, Sigal LJ, Huszar D, Connolly DC.

Mol Cancer Ther. 2015 Apr;14(4):1035-47. doi: 10.1158/1535-7163.MCT-14-0800. Epub 2015 Feb 2.

13.

[Effects of Chinese herbal recipe Weichang'an in inducing apoptosis and related gene expression in human gastric cancer grafted onto nude mice].

Zhao AG, Yang JK, You SF, Li T, Zhao HL, Gu Y, Tang LD, Qiu JX.

Zhong Xi Yi Jie He Xue Bao. 2007 May;5(3):287-97. Chinese. Erratum in: Zhong Xi Yi Jie He Xue Bao. 2007 Jul;5(4):382.

14.

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo.

Rajendran P, Ong TH, Chen L, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Hui KM, Sethi G.

Clin Cancer Res. 2011 Mar 15;17(6):1425-39. doi: 10.1158/1078-0432.CCR-10-1123. Epub 2010 Dec 3.

15.

Luteolin arrests cell cycling, induces apoptosis and inhibits the JAK/STAT3 pathway in human cholangiocarcinoma cells.

Aneknan P, Kukongviriyapan V, Prawan A, Kongpetch S, Sripa B, Senggunprai L.

Asian Pac J Cancer Prev. 2014;15(12):5071-6.

16.

Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells.

Wu X, Yan Q, Zhang Z, Du G, Wan X.

Oncol Rep. 2012 May;27(5):1488-96. doi: 10.3892/or.2012.1670. Epub 2012 Feb 2.

PMID:
22327423
17.

Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway.

Lee JH, Kim C, Kim SH, Sethi G, Ahn KS.

Cancer Lett. 2015 May 1;360(2):280-93. doi: 10.1016/j.canlet.2015.02.024. Epub 2015 Feb 16.

PMID:
25697480
18.

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

Sen M, Pollock NI, Black J, DeGrave KA, Wheeler S, Freilino ML, Joyce S, Lui VW, Zeng Y, Chiosea SI, Grandis JR.

Neoplasia. 2015 Mar;17(3):256-64. doi: 10.1016/j.neo.2015.01.003.

19.

JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling.

Fu LX, Lian QW, Pan JD, Xu ZL, Zhou TM, Ye B.

J Biol Regul Homeost Agents. 2017 Jan-Mar;31(1):51-58.

PMID:
28337870
20.

Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro.

Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG.

World J Gastroenterol. 2016 Apr 28;22(16):4149-59. doi: 10.3748/wjg.v22.i16.4149.

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