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Items: 1 to 20 of 155

1.

The minimal active human SVA retrotransposon requires only the 5'-hexamer and Alu-like domains.

Hancks DC, Mandal PK, Cheung LE, Kazazian HH Jr.

Mol Cell Biol. 2012 Nov;32(22):4718-26. doi: 10.1128/MCB.00860-12. Epub 2012 Sep 24.

2.

The non-autonomous retrotransposon SVA is trans-mobilized by the human LINE-1 protein machinery.

Raiz J, Damert A, Chira S, Held U, Klawitter S, Hamdorf M, Löwer J, Strätling WH, Löwer R, Schumann GG.

Nucleic Acids Res. 2012 Feb;40(4):1666-83. doi: 10.1093/nar/gkr863. Epub 2011 Nov 3.

3.

Retrotransposition of marked SVA elements by human L1s in cultured cells.

Hancks DC, Goodier JL, Mandal PK, Cheung LE, Kazazian HH Jr.

Hum Mol Genet. 2011 Sep 1;20(17):3386-400. doi: 10.1093/hmg/ddr245. Epub 2011 Jun 2.

4.

The RNA polymerase dictates ORF1 requirement and timing of LINE and SINE retrotransposition.

Kroutter EN, Belancio VP, Wagstaff BJ, Roy-Engel AM.

PLoS Genet. 2009 Apr;5(4):e1000458. doi: 10.1371/journal.pgen.1000458. Epub 2009 Apr 24.

5.

Lineage specific evolution of the VNTR composite retrotransposon central domain and its role in retrotransposition of gibbon LAVA elements.

Lupan I, Bulzu P, Popescu O, Damert A.

BMC Genomics. 2015 May 16;16:389. doi: 10.1186/s12864-015-1543-z.

6.

The Engineered SVA Trans-mobilization Assay.

Bock A, Schumann GG.

Methods Mol Biol. 2016;1400:203-22. doi: 10.1007/978-1-4939-3372-3_14.

PMID:
26895056
7.

Hominoid composite non-LTR retrotransposons-variety, assembly, evolution, and structural determinants of mobilization.

Ianc B, Ochis C, Persch R, Popescu O, Damert A.

Mol Biol Evol. 2014 Nov;31(11):2847-64. doi: 10.1093/molbev/mst256. Epub 2014 Sep 12.

PMID:
25216663
8.

Molecular reconstruction of extinct LINE-1 elements and their interaction with nonautonomous elements.

Wagstaff BJ, Kroutter EN, Derbes RS, Belancio VP, Roy-Engel AM.

Mol Biol Evol. 2013 Jan;30(1):88-99. doi: 10.1093/molbev/mss202. Epub 2012 Aug 23.

9.

Rescuing Alu: recovery of new inserts shows LINE-1 preserves Alu activity through A-tail expansion.

Wagstaff BJ, Hedges DJ, Derbes RS, Campos Sanchez R, Chiaromonte F, Makova KD, Roy-Engel AM.

PLoS Genet. 2012;8(8):e1002842. doi: 10.1371/journal.pgen.1002842. Epub 2012 Aug 9.

10.

Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination.

Nazaryan-Petersen L, Bertelsen B, Bak M, Jønson L, Tommerup N, Hancks DC, Tümer Z.

Hum Mutat. 2016 Apr;37(4):385-95. doi: 10.1002/humu.22953. Epub 2016 Feb 4.

PMID:
26929209
11.

The Flow of the Gibbon LAVA Element Is Facilitated by the LINE-1 Retrotransposition Machinery.

Meyer TJ, Held U, Nevonen KA, Klawitter S, Pirzer T, Carbone L, Schumann GG.

Genome Biol Evol. 2016 Oct 30;8(10):3209-3225.

12.

Distinct mechanisms for trans-mediated mobilization of cellular RNAs by the LINE-1 reverse transcriptase.

Garcia-Perez JL, Doucet AJ, Bucheton A, Moran JV, Gilbert N.

Genome Res. 2007 May;17(5):602-11. Epub 2007 Apr 6.

13.

LINE-1 ORF1 protein enhances Alu SINE retrotransposition.

Wallace N, Wagstaff BJ, Deininger PL, Roy-Engel AM.

Gene. 2008 Aug 1;419(1-2):1-6. doi: 10.1016/j.gene.2008.04.007. Epub 2008 Apr 24.

14.

Retrotransposon expression and incorporation of cloned human and mouse retroelements in human spermatozoa.

Lazaros L, Kitsou C, Kostoulas C, Bellou S, Hatzi E, Ladias P, Stefos T, Markoula S, Galani V, Vartholomatos G, Tzavaras T, Georgiou I.

Fertil Steril. 2017 Mar;107(3):821-830. doi: 10.1016/j.fertnstert.2016.12.027. Epub 2017 Jan 27.

PMID:
28139237
15.
16.

SINE Retrotransposition: Evaluation of Alu Activity and Recovery of De Novo Inserts.

Ade C, Roy-Engel AM.

Methods Mol Biol. 2016;1400:183-201. doi: 10.1007/978-1-4939-3372-3_13.

PMID:
26895055
17.

Active human retrotransposons: variation and disease.

Hancks DC, Kazazian HH Jr.

Curr Opin Genet Dev. 2012 Jun;22(3):191-203. doi: 10.1016/j.gde.2012.02.006. Epub 2012 Mar 8. Review.

18.

SVA retrotransposons: Evolution and genetic instability.

Hancks DC, Kazazian HH Jr.

Semin Cancer Biol. 2010 Aug;20(4):234-45. doi: 10.1016/j.semcancer.2010.04.001. Epub 2010 Apr 21. Review.

19.

Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR).

Christian CM, deHaro D, Kines KJ, Sokolowski M, Belancio VP.

Nucleic Acids Res. 2016 Jun 2;44(10):4818-34. doi: 10.1093/nar/gkw277. Epub 2016 Apr 19.

20.

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.

Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG.

Nat Commun. 2016 Jan 8;7:10286. doi: 10.1038/ncomms10286.

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