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22999477,21531636,22321407,27875787,21963276,21903488,20541984,25713108,24008120,21549539,23369882,18189267,23245233,21251889,17161029,22999474,20352612,22124983,18069077,22321408,22120786,30205426,23261824,18650047,22552003,22169059,20655813,20116956,19875262,22344977,21882209,15386498,16567136,19027255,21983198,17428011,18316253,22819204,24811810,21983196,21081292,22366283,19046843,23505096,21872541,21514902,22196804,26245359,20149766,19688816,23339041,26169139,19118970,18986788,18342583,22718742,21393074,22883103,16908225,21945452,24412692,22672845,22113886,19632163,21511546,21315892,22222773,18258496,17446145,20832228,24786221,23266361,21930275,22018980,20371215,25771205,17902196,18977187,22815211,20963772,18723408,19744895,19121909,15639440,22947502,21185793,19358313,19889586,17141585,19662625,19620026,22153330,22677654,19277965,22259043,21882210,17459785,20872909,24835512,23735239,22196803,25575171,22334358,25129411,24389355,22429876,24487058,25703950,24269908,23843078,23146230,25668796,23660248,22821721,22886904,22767645,24706526,24375731,19782650,22867839,28064067,25703948,17706393,24929960,24780702,22344998,20570577,23455073,25864008,25086416,23010480,25240925,23446289,25556066,24037806,23640910,22884475,24122875,25613013,23290921,22917593,24132644,29143972,22623082,23523877,23925904,24782399,24636069,23576027,26492227,22549824,26638035,22766230,24999248,25973544,25010713,24706508,24687287,25108106,28623851,23153646,21803667,23831487,23857175,22763773,24095874,22865648,23892657,24342508,23037995,25016164,23893636,25237707,26095112,25289789,24801995,23798342,23217302,23274625,26512677,25873241,26149245,24802257,23420715,24607696,25899870,23507688,22626892,22495777,23389744,24008168,24274324,25880244,23719316,25459927,22980319,24366214,27903551,24922600,26232561,24359785,27530934,23139245,26859612,19945919,26397206,25128643,26966895,22457166,24357101,24291717,21890435,21834015,26021848,24802389,22275159,20303326,18651605,26297839,22903625,24534567,23973791,22035978,24013191,18947956,22706921,26006134,29518645,25240204,25550191,27552190,26173992,19016230,24295908,25678398,24937809,23545562,34247102,24113236,24210890,25164780,24662144,26363369,23355108,29655233,25456423,24295907,25829058,24463402,26945887,24828095,24788577,17988459,26280281,26114651,23519740,18757149,23270939,27200472,23280750,23135133,24055855,23411022,23357046,23712418,30048897,24424301,28294360,25967583,23010600,24512634,20683584,23832392,26657178,25073106,26187926,23747424,23225735,24497015,27085800,24747147,25376426,25947361,25433911,29193233,25864013,22706896,22213194,25049213,23337906,24920553,30981181,27565758,22311612,28299804,24140655,18499386,21351477,21696904,34519055,28052590,17869472,29575004,29701749,23850933,25770615,24735927,30133708,24704454,27336702,25845449,26011510,24792533,28976575,30062793,25038408,24315982,25617741,23827518,23294995,24898607,24631710,29529709,24552646,25731641,17055347,26297455,26279368,33880775,24327537,24176754,23416370,31412148,31069837,27521987,29315691,22311651,26031660,23839803,29088500,25481295,31077415,19023149,24903899,26222904,23868721,25425175,22222607,26342167,24706520,27232153,25380383,26033334,28370279,22674783,23483550,29334125,23616181,22959824,25222743,26133104,26340560,30073671,23245239,17631426,25194342,23846139,29803687,25016165,26116832,23723093,27038402,25994999,19810008,20055139,25063927,25362596,26010697,12778747,30536684,16893689,34863678,30339948,31212140,19660887,29500935,20719459,17936534,25864014,23644495,23314398,22906796,24134007,30883816,23188706,26551533,23122274,23225496,25005892,21067980,23252280,17457833,22674750,29329091,22893355,24833347,32895916,29206914,29975793,24508679,23411015,25703949,28623772,23692850,25222745,26018409,23147830,23625914,23505290,27183215,24138625,25725321,23314352,29520719,24023058,33886121,29607527,24898405,21748973,28810079,27608059,23624508,23023070,24022056,19167276,19062219,20564607,26684720,26363490,19347967,27107248,21975380,24817673,25880630,25168793,29300894,23261821,23685429,27037980,23369881,23587553,23611843,23732843,25975936,24747521,31325183,21204117,18945568,23474814,28110221,21341376,28873500,23146221,16523529,24588344,23747491,24840406,24424300,29190333,22714983,25264911,23686964,28335025,26390114,23797112,24508675,36278441,24897932,22860257,16104051,25910045,27020929,25497892,22933510,27012305,25090578,26179842,23871562,22722326,24413021,23895851,25725320,25472837,29505960,30172532,17126086,27884874,24668040,26037157,30199748,26440286,24424787,34929736,23225341,25108372,29470848,24203082,24861875,26317321,25298296,24811158,25531877,17113839,22006632,26922579,26093244,26588877,24342512,25958321,25575170,33460195,26409263,26922577,28677837,25657289,33246284,24055750,29314089,25895956,22651958,24739274,28677899,33217008,28618051,25282908,23549759,21963483,29500905,28734159,31899538,24814004,19214962,24828449,23801153,26845200,22674624,24216274,23724654,25404561,16762522,27791319,30773664,19444797,19729260,20080374,25681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Simultaneous determination of esculin and its metabolite esculetin in rat plasma by LC-ESI-MS/MS and its application in pharmacokinetic study.

Li YY, Song YY, Liu CH, Huang XT, Zheng X, Li N, Xu ML, Mi SQ, Wang NS. Li YY, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:27-33. doi: 10.1016/j.jchromb.2012.08.027. Epub 2012 Sep 7. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22999477

Development and validation of a LC-ESI-MS/MS method for the determination of swertiamarin in rat plasma and its application in pharmacokinetics.

Li HL, Peng XJ, He JC, Feng EF, Xu GL, Rao GX. Li HL, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jun 1;879(19):1653-8. doi: 10.1016/j.jchromb.2011.04.003. Epub 2011 Apr 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21531636

Determination of geniposidic acid in rat plasma by LC-MS/MS and its application to in vivo pharmacokinetic studies.

Zheng X, Huang XT, Li N, Li YY, Mi SQ, Wang NS, Liu CH. Zheng X, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 1;887-888:138-42. doi: 10.1016/j.jchromb.2012.01.013. Epub 2012 Jan 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22321407

Simultaneous determination of anemoside B4, phellodendrine, berberine, palmatine, obakunone, esculin, esculetin in rat plasma by UPLC-ESI-MS/MS and its application to a comparative pharmacokinetic study in normal and ulcerative colitis rats.

Yang L, Meng X, Yu X, Kuang H. Yang L, et al. J Pharm Biomed Anal. 2017 Feb 5;134:43-52. doi: 10.1016/j.jpba.2016.11.021. Epub 2016 Nov 11. J Pharm Biomed Anal. 2017. PMID: 27875787

Simultaneous determination of asperosaponin VI and its active metabolite hederagenin in rat plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study.

Zhu H, Ding L, Shakya S, Qi X, Hu L, Yang X, Yang Z. Zhu H, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Nov 15;879(30):3407-14. doi: 10.1016/j.jchromb.2011.09.014. Epub 2011 Sep 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21963276

Simultaneous UFLC-ESI-MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: application to pharmacokinetic studies in rats.

Liu J, Bi Y, Luo R, Wu X. Liu J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 1;879(27):2885-90. doi: 10.1016/j.jchromb.2011.08.018. Epub 2011 Aug 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21903488

Simultaneous determination of active xanthone glycosides, timosaponins and alkaloids in rat plasma after oral administration of Zi-Shen Pill extract for the pharmacokinetic study by liquid chromatography-tandem mass spectrometry.

Cai F, Xu W, Wei H, Sun L, Gao S, Yang Q, Feng J, Zhang F, Chen W. Cai F, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jul 1;878(21):1845-54. doi: 10.1016/j.jchromb.2010.05.024. Epub 2010 May 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20541984

HPLC Determination of Esculin and Esculetin in Rat Plasma for Pharmacokinetic Studies.

Rehman SU, Kim IS, Kang KS, Yoo HH. Rehman SU, et al. J Chromatogr Sci. 2015 Sep;53(8):1322-7. doi: 10.1093/chromsci/bmv014. Epub 2015 Feb 23. J Chromatogr Sci. 2015. PMID: 25713108

Simultaneous quantification of Kirenol and ent-16β,17-dihydroxy-kauran-19-oic acid from Herba Siegesbeckiae in rat plasma by liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies.

Huo L, Jiang Z, Lei M, Wang X, Guo X. Huo L, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 15;937:18-24. doi: 10.1016/j.jchromb.2013.08.019. Epub 2013 Aug 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 24008120

Determination of chamaechromone in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study.

Lou Y, Hu H, Liu Y, Yu Q, Li L, Ping L, Yu L, Jiang H, Zeng S. Lou Y, et al. J Pharm Biomed Anal. 2011 Jul 15;55(5):1163-9. doi: 10.1016/j.jpba.2011.04.009. Epub 2011 Apr 15. J Pharm Biomed Anal. 2011. PMID: 21549539

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